Ceftaroline-resistant, daptomycin-tolerant, and heterogeneous vancomycin-intermediate methicillin-resistant Staphylococcus aureus causing infective endocarditis

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dc.contributor.authorNigo, Masayuki
dc.contributor.authorDiaz, Lorena
dc.contributor.authorCarvajal Ortiz, Lina Paola
dc.contributor.authorTran, Truc T.
dc.contributor.authorRios, Rafael
dc.contributor.authorpanesso, diana
dc.contributor.authorGaravito, Juan D.
dc.contributor.authorMiller, William R.
dc.contributor.authorWanger, Audrey R.
dc.contributor.authorWeinstock, George
dc.contributor.authorMunita, Jose M.
dc.contributor.authorArias, César A.
dc.contributor.authorChambers, Henry
dc.contributor.orcidPanesso, Diana [0000-0002-4049-9702]
dc.contributor.orcidCarvajal Ortiz, Lina Paola [0000-0001-8301-8836]
dc.date.accessioned2020-07-10T16:30:29Z
dc.date.available2020-07-10T16:30:29Z
dc.date.issued2017
dc.description.abstractenglishWe report a case of infective endocarditis (IE) caused by ceftaroline-resistant, daptomycin-tolerant, and heterogeneous vancomycin-intermediate methicillin-resistant S. aureus (MRSA). Resistance to ceftaroline emerged in the absence of drug exposure, and the E447K substitution in the active site of PBP2a previously associated with ceftaroline resistance was identified. Additionally, we present evidence of patient-to-patient transmission of the strain within the same unit. This case illustrates the difficulties in treating MRSA IE in the setting of a multidrug-resistant phenotype.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1128/aac.01235-16
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn1098-6596
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlhttps://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/3423
dc.language.isoeng
dc.publisherAmerican Society for Microbiologyspa
dc.publisher.journalAntimicrobial agents and chemotherapyspa
dc.relation.ispartofseriesAntimicrobial agents and chemotherapy, 1098-6596, Vol. 61, Nro. 3, 2017spa
dc.relation.urihttps://aac.asm.org/content/61/3/e01235-16
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.creativecommons2017-03-01
dc.rights.localAcceso abiertospa
dc.subject.decsFarmacorresistencia bacterianaspa
dc.subject.decsTransmisión de enfermedad infecciosaspa
dc.subject.decsInsuficiencia del tratamientospa
dc.subject.keywordsStaphylococcus aureusspa
dc.subject.keywordsCeftarolinespa
dc.subject.keywordsEndocarditis.spa
dc.titleCeftaroline-resistant, daptomycin-tolerant, and heterogeneous vancomycin-intermediate methicillin-resistant Staphylococcus aureus causing infective endocarditisspa
dc.title.translatedCeftaroline-resistant, daptomycin-tolerant, and heterogeneous vancomycin-intermediate methicillin-resistant Staphylococcus aureus causing infective endocarditisspa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

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