Enterococcal endocarditis: can we win the war?

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dc.contributor.authorMunita, Jose M.
dc.contributor.authorArias, César A.
dc.contributor.authorBeral, Valerie
dc.date.accessioned2020-07-22T21:42:39Z
dc.date.available2020-07-22T21:42:39Z
dc.date.issued2012
dc.description.abstractenglishTreatment of enterococcal infections has long been recognized as an important clinical challenge, particularly in the setting of infective endocarditis (IE). Furthermore, the increase prevalence of isolates exhibiting multidrug resistance (MDR) to traditional anti-enterococcal antibiotics such as ampicillin, vancomycin and aminoglycosides (high-level resistance) poses immense therapeutic dilemmas in hospitals around the world. Unlike IE caused by most isolates of Enterococcus faecalis, which still retain susceptibility to ampicillin and vancomycin, the emergence and dissemination of a hospital-associated genetic clade of multidrug resistant Enterococcus faecium, markedly limits the therapeutic options. The best treatment of IE MDR enterococcal endocarditis is unknown and the paucity of antibiotics with bactericidal activity against these organisms is a cause of serious concern. Although it appears that we are winning the war against E. faecalis, the battle rages on against isolates of multidrug-resistant E. faecium.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1007/s11908-012-0270-8
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn1534-3146
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlhttps://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/3568
dc.language.isoeng
dc.publisherSpringer Naturespa
dc.publisher.journalCurrent infectious disease reportsspa
dc.relation.ispartofseriesCurrent infectious disease reports, 1534-3146, Vol. 14, Nro. 4, 2012, p. 339-349spa
dc.relation.urihttps://link.springer.com/article/10.1007/s11908-012-0270-8
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.creativecommons2012-06-03
dc.rights.localAcceso abiertospa
dc.subject.decsEnterococos resistentes a la vancomicinaspa
dc.subject.decsEndocarditisspa
dc.subject.decsMicrobioma gastrointestinalspa
dc.subject.keywordsInfective endocarditisspa
dc.subject.keywordsEnterococcusspa
dc.subject.keywordsTherapyspa
dc.titleEnterococcal endocarditis: can we win the war?spa
dc.title.translatedEnterococcal endocarditis: can we win the war?spa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

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