Síndrome hemolítico-urémica associada com streptococcus pneumoniae em pediatria: Série de casos

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dc.contributor.authorLeón Guerra, Oscar Javier
dc.contributor.authorGaleano Rodriguez, Ricardo
dc.contributor.authorMorales Camacho, William Javier
dc.contributor.authorPlata Ortiz, Jessica Estefania
dc.contributor.authorMorales Camacho, Maria Alejandra
dc.date.accessioned2020-05-15T19:40:44Z
dc.date.available2020-05-15T19:40:44Z
dc.date.issued2020
dc.description.abstractenglishObjective: To describe a case series of four (4) patients with hemolytic uremic syndrome due to Streptococcus pneumoniae in a level four complexity institution in the city of Bogotá, D.C., Colombia. Cases description: We describe cases of four patients who presented respiratory symptoms and fever. All four patients were in regular conditions on hospital admission, after which they required intensive care and ventilatory support. Upon admission, three cases showed evidence of pleuropulmonary complication. Penicillin-sensitive Streptococcus pneumoniae was isolated in all cases. All patients presented anemia, severe thrombocytopenia, schistocytes on peripheral blood smear, and hyperazotemia. They required blood transfusion and renal replacement therapy during their hospitalization. The patients were diagnosed with hemolytic uremic syndrome due to S. pneumoniae. Three of the four patients had a progressive recovery of the renal function and were discharged after an average of 36 days of hospital stay. The remaining patient had two amputations in the extremities due to thrombotic vascular complications and was discharged after 99 days of hospital stay, requiring hemodialysis every other day. Comments: Hemolytic uremic syndrome due to Streptococcus pneumoniae is a rare but severe complication of invasive pneumococcal disease. Complicated pneumonia is the main condition associated with this entity. It is noteworthy the short period in which these cases were presented, considering the low annual incidence of the disease.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://dx.doi.org/10.1590/1984-0462/2020/38/2018065
dc.identifier.issn0130-0582
dc.identifier.urihttps://hdl.handle.net/20.500.12495/2852
dc.language.isoeng
dc.language.isopor
dc.publisherSociedade De Pediatria De Sao Paulospa
dc.publisher.journalRevista paulista de pediatriaspa
dc.relation.ispartofseriesRevista paulista de pediatria, 0130-0582, Vol. 38, 2020spa
dc.relation.urihttps://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822020000100601&tlng=en
dc.rightsAttribution 4.0 International*
dc.rights.creativecommons2019
dc.rights.localAcceso abiertospa
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subject.decsInformes de casosspa
dc.subject.decsInsuficiencia renalspa
dc.subject.decsMicroangiopatías trombóticasspa
dc.subject.keywordsHemolytic-uremic syndromespa
dc.subject.keywordsStreptococcus pneumoniaespa
dc.subject.keywordsRenal insufficiencyspa
dc.titleSíndrome hemolítico-urémica associada com streptococcus pneumoniae em pediatria: Série de casosspa
dc.title.translatedHemolytic uremic syndrome associated with streptococcus pneumoniae in pediatrics: A case seriesspa
dc.typearticlespa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localartículospa

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