Síndrome hemolítico-urémica associada com streptococcus pneumoniae em pediatria: Série de casos

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Oscar Javier León Guerraa, Ricardo Saul Galeano Rodrígueza, William Javier Morales Camachob_2020.pdf (242.95 KB)
Oscar Javier León Guerraa, Ricardo Saul Galeano Rodrígueza, William Javier Morales Camachob, , Jessica Estefanía Plata Ortizb, María Alejandra Morales Camacho_2020_port.pdf (238.08 KB)

Fecha

2020

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Publicado en

Revista paulista de pediatria, 0130-0582, Vol. 38, 2020

Publicado por

Sociedade De Pediatria De Sao Paulo

URI

https://hdl.handle.net/20.500.12495/2852

URL de la fuente

https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822020000100601&tlng=en

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Abstract

Objective: To describe a case series of four (4) patients with hemolytic uremic syndrome due to Streptococcus pneumoniae in a level four complexity institution in the city of Bogotá, D.C., Colombia. Cases description: We describe cases of four patients who presented respiratory symptoms and fever. All four patients were in regular conditions on hospital admission, after which they required intensive care and ventilatory support. Upon admission, three cases showed evidence of pleuropulmonary complication. Penicillin-sensitive Streptococcus pneumoniae was isolated in all cases. All patients presented anemia, severe thrombocytopenia, schistocytes on peripheral blood smear, and hyperazotemia. They required blood transfusion and renal replacement therapy during their hospitalization. The patients were diagnosed with hemolytic uremic syndrome due to S. pneumoniae. Three of the four patients had a progressive recovery of the renal function and were discharged after an average of 36 days of hospital stay. The remaining patient had two amputations in the extremities due to thrombotic vascular complications and was discharged after 99 days of hospital stay, requiring hemodialysis every other day. Comments: Hemolytic uremic syndrome due to Streptococcus pneumoniae is a rare but severe complication of invasive pneumococcal disease. Complicated pneumonia is the main condition associated with this entity. It is noteworthy the short period in which these cases were presented, considering the low annual incidence of the disease.

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Keywords

Hemolytic-uremic syndrome, Streptococcus pneumoniae, Renal insufficiency

Temáticas

Informes de casos
Insuficiencia renal
Microangiopatías trombóticas

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