Differential prefrontal-like deficit in children after cerebellar astrocytoma and medulloblastoma tumor

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dc.contributor.authorVaquero, Encarna
dc.contributor.authorGómez, Carlos M.
dc.contributor.authorQuintero-Gallego, Eliana A.
dc.contributor.authorGonzález-Rosa, Javier J.
dc.contributor.authorMárquez, Javier
dc.date.accessioned2019-07-02T20:55:37Z
dc.date.available2019-07-02T20:55:37Z
dc.date.issued2008
dc.description.abstractenglishThis study was realized thanks to the collaboration of children and adolescents who had been resected from cerebellar tumors. The medulloblastoma group (CE+, n = 7) in addition to surgery received radiation and chemotherapy. The astrocytoma group (CE, n = 13) did not receive additional treatments. Each clinical group was compared in their executive functioning with a paired control group (n = 12). The performances of the clinical groups with respect to controls were compared considering the tumor's localization (vermis or hemisphere) and the affectation (or not) of the dentate nucleus. Executive variables were correlated with the age at surgery, the time between surgery-evaluation and the resected volume. The executive functioning was assessed by means of WCST, Complex Rey Figure, Controlled Oral Word Association Test (letter and animal categories), Digits span (WISC-R verbal scale) and Stroop test. These tests are very sensitive to dorsolateral PFC and/or to medial frontal cortex functions. The scores for the non-verbal Raven IQ were also obtained. Direct scores were corrected by age and transformed in standard scores using normative data. The neuropsychological evaluation was made at 3.25 (SD = 2.74) years from surgery in CE group and at 6.47 (SD = 2.77) in CE+ group.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1186/1744-9081-4-18
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn1744-9081
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/1478
dc.language.isoeng
dc.publisherBiomed Centralspa
dc.publisher.journalBehavioral and Brain Functionsspa
dc.relation.ispartofseriesBehavioral and Brain Functions, 1744-9081, Vol. 4, 2008, p. 1-16spa
dc.relation.urihttps://behavioralandbrainfunctions.biomedcentral.com/articles/10.1186/1744-9081-4-18
dc.rightsAttribution 4.0 International*
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf442
dc.rights.creativecommons2008
dc.rights.localAcceso abiertospa
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subject.decsMeduloblastomaspa
dc.subject.decsNeoplasias neuroepitelialesspa
dc.subject.decsTest de clasificación de tarjetas de Wisconsinspa
dc.subject.keywordsAnterior Cingulate Cortexspa
dc.subject.keywordsMedulloblastomaspa
dc.subject.keywordsVerbal Fluencyspa
dc.subject.keywordsDigit Spanspa
dc.subject.keywordsWisconsin Card Sorting Testspa
dc.titleDifferential prefrontal-like deficit in children after cerebellar astrocytoma and medulloblastoma tumorspa
dc.typearticlespa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localartículospa

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