Description of high rates of unapparent and simultaneous multiple dengue virus infection in a Colombian jungle settlement

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dc.contributor.authorCastellanos, Jaime
dc.contributor.authorCorolnel-Ruíz, Carolina
dc.contributor.authorParra Alvarez, Shirly
dc.contributor.authorCastilla, Maria-Goretti
dc.contributor.authorCalvo, Eliana
dc.contributor.authorArevalo-Herrera, Myriam
dc.contributor.authorVelandia-Romero, Myriam Lucía
dc.contributor.orcidCastellanos, Jaime [0000-0003-1596-8383]
dc.contributor.orcidVelandia-Romero, Myriam Lucía [0000-0002-3340-7304]
dc.contributor.orcidCoronel-Ruiz, Carolina [0000-0003-2202-5682]
dc.contributor.orcidCalvo, Eliana [0000-0002-9135-0748]
dc.contributor.orcidCorolnel-Ruíz, Carolina [0000-0003-2202-5682]
dc.contributor.orcidCorolnel-Ruíz, Carolina [0000-0003-2202-5682]
dc.date.accessioned2020-11-17T19:02:40Z
dc.date.available2020-11-17T19:02:40Z
dc.description.abstractenglishDengue disease statistics is mainly based on consulting patients with febrile illness, but misdiagnosed and asymptomatic cases are important to measure dengue epidemiology in endemic areas. The main objective of this work was to determine the prevalence of IgM and IgG antibodies or NS1 antigen and viral RNA in a group of healthy volunteers from an isolated village in Colombian Chocó rain forest. It found 51.7% of virologically PCR confirmed asymptomatic cases, despite low IgM seroprevalence. It was confirmed that all four serotypes are in the circulation and in 17.2% of individuals it detected natural coinfections of two or three different serotypes simultaneously. This is the first report in Colombia evaluating viremia in asymptomatic volunteers. These findings pose a big concern about the transmission of dengue virus by asymptomatic individuals because they can spread the virus without taking appropriate control measures.eng
dc.format.mimetypeapplication/pdf
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn0127-5720
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/5066
dc.language.isoeng
dc.publisherMalaysian Society of Parasitology and Tropical Medicine (MSPTM)spa
dc.publisher.journalTropical Biomedicinespa
dc.relation.ispartofseriesTropical Biomedicine, 0127-5720, Vol. 33, No. 2, 2016, p. 375-382spa
dc.relation.urihttps://msptm.org/journal-vol-33-no-2/
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.creativecommons2016
dc.rights.localAcceso abiertospa
dc.subject.decsVirus del denguespa
dc.subject.decsBosque lluvioso -- Colombiaspa
dc.subject.decsInfecciones -- Investigacionesspa
dc.titleDescription of high rates of unapparent and simultaneous multiple dengue virus infection in a Colombian jungle settlementspa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

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