ARGONAUT II study of the in vitro activity of plazomicin against carbapenemase-producing klebsiella pneumoniae
dc.contributor.author | Jacobs, Michael R. | |
dc.contributor.author | Good, Caryn E. | |
dc.contributor.author | Hujer, Andrea M. | |
dc.contributor.author | Abdelhamed, Ayman M. | |
dc.contributor.author | Rhoads, Daniel | |
dc.contributor.author | Hujer, Kristine M. | |
dc.contributor.author | Rudin, Susan D. | |
dc.contributor.author | Domitrovic, T. Nicholas J. | |
dc.contributor.author | Connolly, Lynn E. | |
dc.contributor.author | Krause, Kevin M. | |
dc.contributor.author | Patel, Robin | |
dc.contributor.author | Arias, Cesar A | |
dc.contributor.author | Kreiswirth, Barry N. | |
dc.contributor.author | Rojas, Laura J. | |
dc.contributor.author | D'Souza, Roshan | |
dc.contributor.author | King, C. Richard | |
dc.contributor.author | Brinkac, Lauren M. | |
dc.contributor.author | Nguyen, Kevin | |
dc.contributor.author | Singh, Indresh | |
dc.contributor.author | Fouts, Derrick E. | |
dc.contributor.author | van Duin, David | |
dc.contributor.author | Bonomo, Robert A. | |
dc.date.accessioned | 2020-07-15T17:59:35Z | |
dc.date.available | 2020-07-15T17:59:35Z | |
dc.date.issued | 2020 | |
dc.description.abstractenglish | Plazomicin was tested against 697 recently acquired carbapenem-resistant Klebsiella pneumoniae isolates from the Great Lakes region of the United States. Plazomicin MIC50 and MIC90 values were 0.25 and 1 mg/liter, respectively; 680 isolates (97.6%) were susceptible (MICs of ≤2 mg/liter), 9 (1.3%) intermediate (MICs of 4 mg/liter), and 8 (1.1%) resistant (MICs of >32 mg/liter). Resistance was associated with rmtF-, rmtB-, or armA-encoded 16S rRNA methyltransferases in all except 1 isolate. | eng |
dc.format.mimetype | application/pdf | |
dc.identifier.doi | https://doi.org/10.1128/aac.00012-20 | |
dc.identifier.instname | instname:Universidad El Bosque | spa |
dc.identifier.issn | 1098-6596 | |
dc.identifier.reponame | reponame:Repositorio Institucional Universidad El Bosque | spa |
dc.identifier.repourl | https://repositorio.unbosque.edu.co | |
dc.identifier.uri | https://hdl.handle.net/20.500.12495/3501 | |
dc.language.iso | eng | |
dc.publisher | American Society for Microbiology | spa |
dc.publisher.journal | Antimicrobial agents and chemotherapy | spa |
dc.relation.ispartofseries | Antimicrobial agents and chemotherapy, 1098-6596, Vol. 64, Nro. 5, 2020 | spa |
dc.relation.uri | https://aac.asm.org/content/64/5/e00012-20.long | |
dc.rights.accessrights | https://purl.org/coar/access_right/c_abf2 | |
dc.rights.accessrights | info:eu-repo/semantics/openAccess | |
dc.rights.accessrights | Acceso abierto | |
dc.rights.creativecommons | 2020-04-21 | |
dc.rights.local | Acceso abierto | spa |
dc.subject.decs | Enterobacteriaceae resistentes a los carbapenémicos | spa |
dc.subject.decs | Carbapenémicos | spa |
dc.subject.decs | Proteínas asociadas a resistencia a múltiples medicamentos | spa |
dc.subject.keywords | Klebsiella | spa |
dc.subject.keywords | Antibiotic resistance | spa |
dc.subject.keywords | Carbapenemase | spa |
dc.title | ARGONAUT II study of the in vitro activity of plazomicin against carbapenemase-producing klebsiella pneumoniae | spa |
dc.title.translated | ARGONAUT II study of the in vitro activity of plazomicin against carbapenemase-producing klebsiella pneumoniae | spa |
dc.type.coar | https://purl.org/coar/resource_type/c_6501 | |
dc.type.driver | info:eu-repo/semantics/article | |
dc.type.hasversion | info:eu-repo/semantics/publishedVersion | |
dc.type.local | Artículo de revista |
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