Infiltrating/sealing proximal caries lesions: A 3-year randomized clinical tria

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dc.contributor.authorMartignon, Stefania
dc.contributor.authorEkstrand, Kim Rud
dc.contributor.authorGomez, Juliana
dc.contributor.authorLara, Juan Sebastián
dc.contributor.authorCortés Páez, Andrea
dc.contributor.orcidMartignon, Stefania [0000-0002-6505-8356]
dc.contributor.orcidCortés Páez, Andrea [orcid.org/0000-0001-6472-8330]
dc.date.accessioned2020-07-24T21:00:04Z
dc.date.available2020-07-24T21:00:04Z
dc.date.issued2012
dc.description.abstractenglishThis randomized split-mouth controlled clinical trial aimed at assessing the therapeutic effects of infiltration vs. sealing for controlling caries progression on proximal surfaces. Out of 90 adult students/patients assessed at university clinics and agreeing to participate, 39, each with 3 proximal lesions identified radiographically around the enamel-dentin junction to the outer third of the dentin, were included. Lesions were randomly allocated for treatment to test-A (Infiltration: ICON-pre-product; DMG), test-B (Sealing: Prime-Bond-NT; Dentsply), or control-C (Placebo). Primary outcome after 1, 2, and 3 yrs of radiographically observed lesion progression was assessed by an independent examiner blinded to groups, using pair-wise and digital-subtraction readings. No adverse events occurred. In 37 participants assessed after 3 yrs, 10 lesions (A-4; B-2; C-4) progressed deep into dentin and needed operative treatment. The 3-year therapeutic effect, based on pair-wise radiographic readings between infiltration and placebo, was 37.8% (95%CI: 20.5-55.2%) and that between sealing and placebo was 29.7% (95%CI: 20.2-35.0%). One-year follow-up digital-subtraction readings showed significant differences in lesion progression between infiltration and placebo (P = 0.0012) and between sealing and placebo (P = 0.0269). The study showed that infiltration and sealing are significantly better than placebo treatment for controlling caries progression on proximal lesions. No significant difference was seen between infiltration and sealing (ClinicalTrials.gov number CT01417832).eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1177%2F0022034511435328
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn0022-0345
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlhttps://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/3578
dc.language.isoeng
dc.publisherSAGEspa
dc.publisher.journalJournal of dental researchspa
dc.relation.ispartofseriesJournal of dental research, 0022-0345, Vol. 91, Nro. 3, 2012, p. 288-292spa
dc.relation.urihttps://journals.sagepub.com/doi/10.1177/0022034511435328
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.creativecommons2012-01-17
dc.rights.localAcceso abiertospa
dc.subject.decsEsmalte dentalspa
dc.subject.decsSelladores de fosas y fisurasspa
dc.subject.decsEnsayo clínicospa
dc.subject.keywordsCaries treatmentspa
dc.subject.keywordsClinical studies/trialsspa
dc.subject.keywordsRadiographyspa
dc.titleInfiltrating/sealing proximal caries lesions: A 3-year randomized clinical triaspa
dc.title.translatedInfiltrating/sealing proximal caries lesions: A 3-year randomized clinical triaspa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

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