Factores de riesgo para craneosinostosis simples: Revisión temática

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dc.contributor.advisorGonzalez Carrera, María Clara
dc.contributor.advisorMora Díaz, Ingrid Isabel
dc.contributor.authorGalbán Zavala, Elizabeth Cristina
dc.contributor.authorSerna, Marlen Viviana
dc.contributor.authorVargas Barragán, Laura Catalina
dc.date.accessioned2024-09-04T14:56:44Z
dc.date.available2024-09-04T14:56:44Z
dc.date.issued2024-05
dc.description.abstractAntecedentes: La craneosinostosis (CS), es una afección que impacta a la población pediátrica en todo el mundo, se define por el cierre prematuro de una o más suturas que conforman la bóveda craneana. Los factores de riesgo asociados a esta condición han sido identificados, pero su vinculación precisa con la enfermedad requiere una revisión de la literatura actual. En este contexto, resulta crucial explorar y esclarecer la relación entre los factores de riesgo mencionados y la manifestación de la CS. Este análisis contribuirá no solo a una comprensión más profunda de la patología, sino también a informar estrategias preventivas y terapéuticas más efectivas en el ámbito pediátrico. Objetivos: Identificar cuáles son los factores de riesgo para el desarrollo de craneosinostosis simples en la literatura. Materiales y Métodos: Se llevó a cabo una búsqueda de literatura sobre los factores de riesgo asociados al desarrollo de CS simple utilizando algoritmos específicos, en bases de datos especializadas como PubMed y EMBASE. La selección de artículos se limitó al período desde 2014 hasta la fecha y se enfocó en aquellos que abordaron factores de riesgo. Los factores de riesgo de interés fueron genética, sexo, edad, agentes teratógenos, comorbilidades maternas, comorbilidades fetales, raza, y nivel socioeconómico. Resultados: En PubMed se obtuvieron 1,689,657 resultados, en EMBASE se encontraron 7,254,647 resultados, reducidos a una totalidad de 131 referencias preliminares. Se seleccionaron 25 referencias para la revisión temática. Se utilizaron 7 artículos sobre genética, 4 sobre sexo, 1 sobre edad parental y 5 sobre agentes teratógenos para identificar si constituyen factor de riesgo para desarrollar CS. Se utilizaron 6 artículos para consultar si las comorbilidades tanto maternas como fetales son factor de riesgo para la CS. Se encontraron 2 artículos para analizar si la raza es un factor de riesgo para la aparición de CS. No se encontraron artículos que relacionaran nivel socioeconómico como etiología para CS por lo cual no pudo ser evaluado. Conclusiones: Aunque la CS simple tiene una etiología compleja y desconocida, se conoce que los múltiples componentes que permiten su desarrollo en la osteogénesis están relacionados como mutaciones en los genes de Axin2, TWIST1 y ALX4, la exposición a teratógenos como metales, medicamentos como la tranilcipromina, progesterona, valproato, antidepresivos, disfunciones tiroideas maternas, diabetes materna, múltiples gestaciones y la presentación pelviana del bebé. Se necesita más evidencia para determinar si otras comorbilidades maternas como la obesidad e infecciones virales durante el embarazo, la raza, el nivel socioeconómico y la edad parental forman parte de esos múltiples factores que bren paso a la CS, debido a la falta de evidencia al respecto.
dc.description.abstractenglishBackground: Craniosynostosis (CS) is a premature closure of one or more sutures of the skull and it is a condition that affects the paediatric population worldwide. The risk factors have been identified but their precise relation with the condition require a review of current literature, which will contribute to a better understanding of the pathology, strategies and effective treatments. Objectives: to identify the risk factors for simple craniosynostosis. Materials and methods: a literature search was carried with specific algorithms in database such as Pubmed and EMBASE, article selection was limited between 2014 and the current date and risk factors were genetics, sex, age, teratogenic agents, maternal comorbidities, faetal comorbidities, race and socioeconomic level. Results: There were 1.689.657 results in Pubmed, 7.254.647 in EMBASE, from which 131 were selected; 25 references were selected for the review, seven about genetics, four about sex, one about parental age and five about teratogenic agents and if they constitute a risk factor, six to consult if maternal and faetal comorbidities were a factor and two to analyse if risk is a factor. No articles relative to socioeconomic level as an aetiology were found, so it could not be assessed. Conclusions: CS has a complex and unknown aetiology, but the multiple components for its development during osteogenesis are known to be related to Axin2, TWIST1 and ALX4 genes, exposure to metals, tranylcypromine, progesterone, valproate, antidepressants, maternal thyroid dysfunctions, maternal diabetes, multiple gestations and the baby’s pelvic presentation. Further evidence is required to determine if other comorbidities such as obesity, viral infections during pregnancy, race, socioeconomic level and parental age are part of the multiple factors for CS.
dc.description.degreelevelPregradospa
dc.description.degreenameOdontólogospa
dc.description.sponsorshipGrupo de investigación UMIMC - Unidad de Manejo Integral de Malformaciones Craneofaciales
dc.format.mimetypeapplication/pdf
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/12933
dc.language.isoes
dc.publisher.facultyFacultad de Odontologíaspa
dc.publisher.grantorUniversidad El Bosquespa
dc.publisher.programOdontologíaspa
dc.relation.referencesTirado-Pérez Irina Suley, Sequeda-Monterroza José Fernando, Zarate-Vergara Andrea Carolina. Craneosinostosis: Revisión de literatura. Univ. Salud. 2016; 18( 1 ): 182-9.
dc.relation.referencesNavia, M. I. O., Alvarez-García, D., Gempeler, A., & Velásquez, F. (2022). Craneosinostosis: revisión de la literaturaActa Pediátrica de México, 43(3), 179-192
dc.relation.referencesKajdic N, Spazzapan P, Velnar T. Craniosynostosis - Recognition, clinical characteristics, and treatment. Bosn J Basic Med Sci. 2017;18(2).
dc.relation.referencesTimberlake AT, Persing JA. Genetics of nonsyndromic craniosynostosis. Plast Reconstr Surg. 2018;141(6):1508–16
dc.relation.referencesWang JC, Nagy L, Demke JC. Syndromic craniosynostosis. Facial Plast Surg Clin North Am. 2016;24(4):531–43.
dc.relation.referencesWilkie AOM, Johnson D, Wall SA. Clinical genetics of craniosynostosis. Curr Opin Pediatr [Internet]. 2017;29(6):622–8.
dc.relation.referencesGoldberg O, Moretti M, Levy A, Koren G. Exposure to nitrofurantoin during early pregnancy and congenital malformations: A systematic review and meta-analysis. J Obstet Gynaecol Can. 2015;37(2):150–6.
dc.relation.referencesLin Y, Pan I-W, Harris DA, Luerssen TG, Lam S. The impact of insurance, race, and ethnicity on age at surgical intervention among children with nonsyndromic craniosynostosis. J Pediatr. 2015;166(5):1289–96.
dc.relation.referencesKronig SAJ, Kronig ODM, Vrooman HA, Veenland JF, Van Adrichem LNA. New diagnostic approach of the different types of isolated craniosynostosis. Eur J Pediatr. 2021;180(4):1211–7.
dc.relation.referencesBennett KG, Vick AD, Ettinger RE, Archer SM, Vercler CJ, Buchman SR. Age at craniosynostosis surgery and its impact on ophthalmologic diagnoses: A single-center retrospective review. Plast Reconstr Surg. 2019;144(3):696–701.
dc.relation.referencesVillanueva Alfonso R. Diccionario MOSBY : medicina, enfermería y ciencias de la salud. 5th ed. Elsevier Espana; 1999.
dc.relation.referencesSenado Dumoy J. Los factores de riesgo. Rev Cubana Med Gen Integr. 1999 Ago; 15( 4 ): 446-452.
dc.relation.referencesReal Academia Española. Diccionario de la lengua Española. Vigesimotercera edición. Versión normal. Grupo Planeta; 2016.
dc.relation.referencesStanford Medicine, Children's Health. Descripción general de teratógenos.
dc.relation.referencesInstitutos Nacionales de Salud, Insituto Nacional del Cancer. Diccionario de cancer, Nivel Socioeconómico.
dc.relation.referencesTwigg SRF, Wilkie AOM. A genetic-pathophysiological framework for craniosynostosis. Am J Hum Genet. 2015;97(3):359–77.
dc.relation.referencesWalters ME, Lacassie Y, Azamian M, Franciskovich R, Zapata G, Hernandez PP, et al. Vertical transmission of a large calvarial ossification defect due to heterozygous variants of ALX4 and TWIST1. Am J Med Genet A. 2021;185(3):916–22.
dc.relation.referencesBessenyei B, Nagy A, Szakszon K, Mokánszki A, Balogh E, Ujfalusi A, et al. Clinical and genetic characteristics of craniosynostosis in Hungary. Am J Med Genet A [Internet]. 2015 [cited 2024 Feb 26];167(12):2985–91. Available from: https://pubmed.ncbi.nlm.nih.gov/26289989/
dc.relation.referencesBlessing M, Gallagher ER. Epidemiology, genetics, and pathophysiology of craniosynostosis. Oral Maxillofac Surg Clin North Am [Internet]. 2022;34(3):341–52. Available from: http://dx.doi.org/10.1016/j.coms.2022.02.001
dc.relation.referencesDurham EL, Howie RN, Cray JJ. Gene/environment interactions in craniosynostosis: A brief review. Orthod Craniofac Res [Internet]. 2017;20(S1):8–11. Available from: https://pubmed.ncbi.nlm.nih.gov/28643932/
dc.relation.referencesMontes I, Sánchez GV. CRANEOSINOSTOSIS: EXPERIENCIA EN EL HOSPITAL UNIVERSITARIO DEL VALLE 2007 – 2015. Gp. 2016;17(3).
dc.relation.referencesUrhoj SK, Mortensen LH, Nybo Andersen A-M. Advanced paternal age and risk of musculoskeletal congenital anomalies in offspring. Birth Defects Res B Dev Reprod Toxicol [Internet]. 2015;104(6):273–80. Available from: http://dx.doi.org/10.1002/bdrb.21167
dc.relation.referencesXu C, Xu J, Zhang X, Xu S, Liu Q, Weng Z, et al. Serum nickel is associated with craniosynostosis risk: Evidence from humans and mice. Environ Int [Internet]. 2021;146(106289):106289. Available from: http://dx.doi.org/10.1016/j.envint.2020.106289
dc.relation.referencesHoyt AT, Canfield MA, Romitti PA, et al. Associations between maternal periconceptional exposure to secondhand tobacco smoke and major birth defects. Am J Obstet Gynecol 2016;215:613.e1-11.
dc.relation.referencesVerberne EA, de Haan E, van Tintelen JP, Lindhout D, van Haelst MM. Fetal methotrexate syndrome: A systematic review of case reports. Reprod Toxicol. 2019;87:125–39.
dc.relation.referencesCarmichael SL, Ma C, Rasmussen SA, Cunningham ML, Browne ML, Dosiou C, et al. Craniosynostosis and risk factors related to thyroid dysfunction. Am J Med Genet A. 2015;167(4):701–7.
dc.relation.referencesSánchez N, Juárez-Balarezo J, Olhaberry M, González-Oneto H, Muzard A, Mardonez MJ, et al. Depression and antidepressants during pregnancy: Craniofacial defects due to stem/progenitor cell deregulation mediated by serotonin. Front Cell Dev Biol. 2021;9
dc.relation.referencesSchraw JM, Woodhouse JP, Langlois PH, Canfield MA, Scheuerle AE, Agopian AJ, et al. Risk factors and time trends for isolated craniosynostosis. Birth Defects Res. 2021;113(1):43–54.
dc.relation.referencesPlakas S, Anagnostou E, Plakas AC, Piagkou M. High risk factors for craniosynostosis during pregnancy: A case-control study. Eur J Obstet Gynecol Reprod Biol X [Internet]. 2022;14(100147):100147. Disponible en: http://dx.doi.org/10.1016/j.eurox.2022.100147
dc.relation.referencesSergesketter AR, Elsamadicy AA, Lubkin DT, Krucoff KB, Krucoff MO, Muh CR. Characterization of perinatal risk factors and complications associated with nonsyndromic craniosynostosis. J Craniofac Surg. 2019;30(2):334–8
dc.relation.referencesXu J, Yan Q, Song C, Liang J, Zhao L, Zhang X, et al. An Axin2 mutation and perinatal risk factors contribute to sagittal craniosynostosis: evidence from a Chinese female monochorionic diamniotic twin family. Hereditas [Internet]. 2021;158(1). Available from: https://pubmed.ncbi.nlm.nih.gov/34134783/
dc.relation.referencesSacks GN, Skolnick GB, Trachtenberg A, Naidoo SD, Lopez J, Oh AK, et al. The impact of ethnicity on craniosynostosis in the United States. J Craniofac Surg [Internet]. 2019;30(8):2526–9. Available from: http://dx.doi.org/10.1097/scs.0000000000006009
dc.relation.referencesAnderson IA, Goomany A, Bonthron DT, Bellew M, Liddington MI, Smith IM, et al. Does patient ethnicity affect site of craniosynostosis?: Clinical article. J Neurosurg Pediatr [Internet]. 2014;14(6):682–7. Available from: http://dx.doi.org/10.3171/2014.9.peds14123
dc.relation.referencesBradley CM, Alderman BW, Williams MA, Checkoway H, Fernbach SK, Greene C, et al. Parental occupations as risk factors for craniosynostosis in offspring. Epidemiology. 1995;6:306–10.
dc.relation.referencesBarik M, Bajpai M, Das RR, Panda SS. Study of environmental and genetic factors in children with craniosynostosis: A case-control study. J Pediatr Neurosci. 2013 May;8(2):89-92. doi: 10.4103/1817-1745.117833. PMID: 24082921; PMCID: PMC3783739.
dc.relation.referencesLajeunie E, Merrer ML, Marchac D, Renier D. Syndromal and nonsyndromal primary trigonocephaly: Analysis of a series of 237 patients. Am J Med Genet [Internet]. 1998;75(2):211–5. Available from: http://dx.doi.org/10.1002/(sici)1096-8628(19980113)75:2
dc.relation.referencesArcher NP, Langlois PH, Suarez L, Brender J, Shanmugam R. Association of paternal age with prevalence of selected birth defects. Birth Defects Res A Clin Mol Teratol [Internet]. 2007;79(1):27–34. Available from: http://dx.doi.org/10.1002/bdra.20316
dc.relation.referencesBérard A, Zhao J-P, Sheehy O. Antidepressant use during pregnancy and the risk of major congenital malformations in a cohort of depressed pregnant women: an updated analysis of the Quebec Pregnancy Cohort. BMJ Open 2017;7:e013372. doi:10.1136/bmjopen-2016- 013372
dc.relation.referencesReefhuis J, Devine O, Friedman JM, Louik C, Honein MA. Specific SSRIs and birth defects: bayesian analysis to interpret new data in the context of previous reports. BMJ [Internet]. 2015;h3190. Available from: http://dx.doi.org/10.1136/bmj.h3190
dc.relation.referencesSinger S, Bower C, Southall P, Goldblatt J. Craniosynostosis in Western Australia, 1980-1994: A population-based study. Am J Med Genet [Internet]. 1999;83(5):382–7. Available from: https://pubmed.ncbi.nlm.nih.gov/10232748/
dc.rightsAtribución-NoComercial-CompartirIgual 4.0 Internacional
dc.rights.accessrightshttp:/purl.org/coar/access_right/c_abf2/
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.localAcceso abiertospa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/
dc.subjectCraneosinostosis
dc.subjectFactor de riesgo
dc.subjectEtiología
dc.subjectRevisión de literatura
dc.subjectGenética
dc.subject.keywordsCraniosynostosis
dc.subject.keywordsRisk factors
dc.subject.keywordsAetiology
dc.subject.keywordsLiterature review
dc.subject.keywordsGenetics
dc.subject.nlmWU 100
dc.titleFactores de riesgo para craneosinostosis simples: Revisión temática
dc.title.translatedRisk factors for simple craniosynostosis: Thematic review
dc.type.coarhttps://purl.org/coar/resource_type/c_7a1f
dc.type.coarversionhttps://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.driverinfo:eu-repo/semantics/bachelorThesis
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersion
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