Determinación de la carga de enfermedad de Colitis Ulcerativa en Colombia 2010 a 2020

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dc.contributor.advisorPorras Ramírez , Alexandra
dc.contributor.authorGonzalez, Maria
dc.date.accessioned2024-08-16T19:43:34Z
dc.date.available2024-08-16T19:43:34Z
dc.date.issued2024-08
dc.description.abstractIntroducción: La carga global de enfermedad es un indicador desarrollado para abordar 3 problemas principales: Incorporar condiciones no fatales al estado de salud, producir valoraciones de dicho estado de salud objetivas, medir la costó-efectividad de intervenciones en salud para adecuado manejo de los recursos. La colitis ulcerativa es un desorden crónico inflamatorio del colon que causa una inflamación continua de la mucosa extendiéndose desde el colon proximal hasta el recto con ciertas variaciones. La etiología de la colitis ulcerativa sigue siendo un tema de debate. Sin embargo, la evidencia sugiere que posee un componente autoinmune. El costo estimado de la colitis ulcerativa en Estados Unidos puede variar entre los 8.1 y 14.9 billones de dólares. En Colombia se encuentran reportes de prevalencia de la enfermedad sin embargo no está descrito la carga de enfermedad de esta enfermedad en la población colombiana. Objetivos: este estudio pretende estimar la carga de enfermedad de colitis ulcerativa en Colombia durante los años 2010 a 2020 desagregado por grupos de edad. Metodología: es un estudio de carga de enfermedad. Para estimar la prevalencia se realizó una búsqueda a través de los registros del SISPRO basado en la información almacenada en el sistema de Registro Individual de Prestación de Servicios de Salud (RIPS). Se estimaron los DALYs a partir de la suma de YLL y YLD de acuerdo con la metodología propuesta por la OMS del año 2013. Resultados: La prevalencia anual de colitis ulcerativa fue de 8 a 26 x 100.000 habitantes y esta aumenta con la edad siendo el grupo de edad de 70 a 79 el más alto. La proporción de mortalidad llega hasta 0.2 x 100.00’ habitantes donde también se evidencia un aumento en la proporción de mortalidad con la edad principalmente en los mayores de 80 años. Con respecto a los DALYs cumplen con la misma donde la edad es directamente proporcional a los años de vida ajustados por discapacidad. Conclusión: En Colombia la carga de enfermedad para Colitis Ulcerativa, durante el periodo de estudio 2010 a 2020 presenta una tendencia irregular con respecto a los DALYs, el número de DALYs aumentan cronológicamente con la edad.
dc.description.abstractenglishIntroduction: The global burden of disease is an indicator developed to address 3 main problems: Incorporating non-fatal conditions into the health status, producing objective assessments of said health status, measuring the cost-effectiveness of health interventions for adequate resource management. Ulcerative colitis is a chronic inflammatory disorder of the colon that causes continuous inflammation of the mucosa extending from the proximal colon to the rectum with certain variations. The etiology of ulcerative colitis remains a matter of debate. However, evidence suggests that it has an autoimmune component. The estimated cost of ulcerative colitis in the United States may vary between 8.1 and 14.9 billion dollars. In Colombia there are reports of the prevalence of the disease, however the burden of this disease in the Colombian population is not described. Objectives: This study aims to estimate the disease burden of ulcerative colitis in Colombia during the years 2010 to 2020 disaggregated by age groups. Methodology: It is a disease burden study. To estimate the prevalence, a search was carried out through the SISPRO records based on the information stored in the Individual Registry of Health Services Provision (RIPS) system. DALYs were estimated from the sum of YLL and YLD according to the methodology proposed by the WHO in 2013. Results: The annual prevalence of ulcerative colitis was 8 to 26 x 100,000 inhabitants and this increases with age, with the age group from 70 to 79 being the highest. The mortality rate reaches up to 0.2 x 100,000 inhabitants where an increase in the mortality rate with age is also evident, mainly in those over 80 years of age. Regarding DALYs, they comply with the same trend where age is directly proportional to disability-adjusted life years. Conclusion: In Colombia, the disease burden for Ulcerative Colitis, during the study period 2010 to 2020, shows an irregular trend with respect to DALYs, the number of DALYs increases chronologically with age.
dc.description.degreelevelMaestríaspa
dc.description.degreenameMagíster en Epidemiologíaspa
dc.format.mimetypeapplication/pdf
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/12887
dc.language.isoes
dc.publisher.facultyFacultad de Medicinaspa
dc.publisher.grantorUniversidad El Bosquespa
dc.publisher.programMaestría en Epidemiologíaspa
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dc.rightsAttribution-NonCommercial-ShareAlike 4.0 Internationalen
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.localAcceso abiertospa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/
dc.subjectColitis Ulcerosa
dc.subjectCarga global de enfemedad
dc.subjectAños de vida ajustados por incapacidad
dc.subject.keywordsUlcerative Colitis
dc.subject.keywordsGlobal burden disease
dc.subject.keywordsDisability Adjusted Life Years
dc.subject.nlmWA 105
dc.titleDeterminación de la carga de enfermedad de Colitis Ulcerativa en Colombia 2010 a 2020
dc.title.translatedDetermination of the burden of Ulcerative Colitis in Colombia from 2010 to 2020
dc.type.coarhttps://purl.org/coar/resource_type/c_bdcc
dc.type.coarversionhttps://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.driverinfo:eu-repo/semantics/masterThesis
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersion
dc.type.localTesis/Trabajo de grado - Monografía - Maestríaspa

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