Serious and infrequent neurological complications in hospitalized patients with COVID19

dc.contributor.authorLópez-Hortúa, Maira A.
dc.contributor.authorRodríguez-Hernández, Pablo Andrés
dc.contributor.authorAlviarez-Chaustre, Kerly
dc.contributor.authorRivera-Hernández, Stefany
dc.contributor.authorSánchez-Barrero, Carlos Andrés
dc.contributor.authorValderrama-Mendoza, Nelson
dc.contributor.authorMiranda-Acosta, Yeiris
dc.contributor.authorTorres-Bayona, Sergio Andrés
dc.date.accessioned2022-02-09T20:10:11Z
dc.date.available2022-02-09T20:10:11Z
dc.date.issued2022-06
dc.description.abstractBackground SARS-CoV-2 virus infection may affect other organs including the nervous system with variable neurological manifestations, even some research has reported that SARS-CoV-2 can be found in the brain parenchyma and / or in the cerebrospinal fluid (CSF). Although these reports of neurological involvement secondary to COVID-19 has increased, the clinical manifestations and the forms of neurological invasion is not fully understood. Objectives In this paper, we report a case series of patients with SARS-CoV-2 infection with involvement of the nervous system and its neurological complications. In addition, a bibliographic review was developed in different databases with the aim of expanding information on neurological complications and the pathophysiological mechanisms of invasion to the nervous system. Case report Case 1, a 79 year old male developed an infarct of the head of the caudate nucleus and thrombosis of the superior longitudinal sinus. Case 2, a 62 year old female developed an intraparenchymal hemorrhage in the left parietal lobe while hospitalized and COVID19 encephalitis was diagnosed. Case 3, a 59 year old healthy male developed a Fisher IV subarachnoid hemorrhage by aneurysmal origin of the right middle cerebral artery and right temporal intraparenchymal hematoma, due to rapid and severe neurological impairment new brain images was performed showing a right cerebellar ischemic stroke leading to compression of the cistern and brainstem. Conclusions In these cases, the surgery goal was relieved symptoms, neurologic functional recovery, and life survival. We considered its diffusion and knowledge as imperative for all practitioners involved in the care of this patient.spa
dc.description.abstractenglishBackground SARS-CoV-2 virus infection may affect other organs including the nervous system with variable neurological manifestations, even some research has reported that SARS-CoV-2 can be found in the brain parenchyma and / or in the cerebrospinal fluid (CSF). Although these reports of neurological involvement secondary to COVID-19 has increased, the clinical manifestations and the forms of neurological invasion is not fully understood. Objectives In this paper, we report a case series of patients with SARS-CoV-2 infection with involvement of the nervous system and its neurological complications. In addition, a bibliographic review was developed in different databases with the aim of expanding information on neurological complications and the pathophysiological mechanisms of invasion to the nervous system. Case report Case 1, a 79 year old male developed an infarct of the head of the caudate nucleus and thrombosis of the superior longitudinal sinus. Case 2, a 62 year old female developed an intraparenchymal hemorrhage in the left parietal lobe while hospitalized and COVID19 encephalitis was diagnosed. Case 3, a 59 year old healthy male developed a Fisher IV subarachnoid hemorrhage by aneurysmal origin of the right middle cerebral artery and right temporal intraparenchymal hematoma, due to rapid and severe neurological impairment new brain images was performed showing a right cerebellar ischemic stroke leading to compression of the cistern and brainstem. Conclusions In these cases, the surgery goal was relieved symptoms, neurologic functional recovery, and life survival. We considered its diffusion and knowledge as imperative for all practitioners involved in the care of this patient.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.inat.2022.101493
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn2214-7519
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/6778
dc.language.isoeng
dc.publisherElsevier B.V.spa
dc.publisher.journalInterdisciplinary Neurosurgeryspa
dc.relation.ispartofseriesInterdisciplinary Neurosurgery, 2214-7519, Vol 28, 2022spa
dc.relation.urihttps://www.sciencedirect.com/science/article/pii/S221475192200007X
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.localAcceso abiertospa
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectManifestaciones neuroquirúrgicasspa
dc.subjectSistema nervioso centralspa
dc.subject.keywordsCOVID-19spa
dc.subject.keywordsSARS-CoV-2spa
dc.subject.keywordsNeurosurgical manifestationsspa
dc.subject.keywordsCentral nervous systemspa
dc.titleSerious and infrequent neurological complications in hospitalized patients with COVID19spa
dc.title.translatedSerious and infrequent neurological complications in hospitalized patients with COVID19spa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.coarversionhttps://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

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