Comparación de la QRT-PCR y Nested PCR para el diagnóstico de infección por Arbovirus en muestras de individuos con síndrome febril

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dc.contributor.advisorCoronel Ruiz, Carolina
dc.contributor.authorBula Calderon, Lorenzo Jose
dc.contributor.authorPino Dubois, Isabella
dc.date.accessioned2024-11-08T21:23:42Z
dc.date.available2024-11-08T21:23:42Z
dc.date.issued2023-12
dc.description.abstractEl virus del dengue (DENV), el virus del chikungunya (CHIKV) y el virus del zika (ZIKV) son virus transmitidos por artrópodos agentes de enfermedades de importancia en salud pública. Las infecciones producidas por estos virus presentan síntomas inespecíficos, que dificultan la identificación temprana y el establecimiento del diagnóstico. La confirmación de casos por el laboratorio se basa en la aplicación de una prueba serológica, y de la prueba molecular que permite identificar el ARN del virus. Esta última se realiza solo en laboratorios de referencia para la confirmación del diagnóstico en casos severos o fatales, debido a la limitación de recursos y disponibilidad de estas pruebas.
dc.description.abstractenglishDengue virus (DENV), chikungunya virus (CHIKV), and Zika virus (ZIKV) are arthropod-borne viruses that are agents of diseases of public health importance. Infections caused by these viruses present with non-specific symptoms, making early identification and diagnosis challenging. Laboratory confirmation of cases relies on the application of a serological test and molecular tests that identifies viral RNA. Molecular diagnosis is performed only in reference laboratories to confirm diagnosis for severe or fatal cases, due to resource limitations and test availability in endemic areas.
dc.description.degreelevelPregradospa
dc.description.degreenameMédico Cirujanospa
dc.format.mimetypeapplication/pdf
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/13164
dc.language.isoes
dc.publisher.facultyFacultad de Medicinaspa
dc.publisher.grantorUniversidad El Bosquespa
dc.publisher.programMedicinaspa
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dc.rightsAtribución-NoComercial-CompartirIgual 4.0 Internacional
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.localAcceso abiertospa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/
dc.subjectArbovirosis
dc.subjectDengue
dc.subjectChikungunya
dc.subjectZika
dc.subjectDiagnóstico molecular
dc.subject.keywordsArbovirosis
dc.subject.keywordsDengue,
dc.subject.keywordsChikungunya
dc.subject.keywordsZika
dc.subject.keywordsMolecular diagnosis
dc.subject.nlmW100
dc.titleComparación de la QRT-PCR y Nested PCR para el diagnóstico de infección por Arbovirus en muestras de individuos con síndrome febril
dc.title.translatedComparison of QRT-PCR and nested pcr for diagnosis of arbovirus infection in samples from individuals with febrile syndrome
dc.type.coarhttps://purl.org/coar/resource_type/c_7a1f
dc.type.coarversionhttps://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.driverinfo:eu-repo/semantics/bachelorThesis
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersion
dc.type.localTesis/Trabajo de grado - Monografía - Pregradospa

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