Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems
dc.contributor.author | Cork, M.A. | |
dc.contributor.author | Henry, N.J. | |
dc.contributor.author | Watson, S. | |
dc.contributor.author | Croneberger, A.J. | |
dc.contributor.author | Baumann, M. | |
dc.contributor.author | Letourneau, I.D. | |
dc.contributor.author | Yang, M. | |
dc.contributor.author | Serfes, A.L. | |
dc.contributor.author | Abbas, J. | |
dc.contributor.author | Abbasi, N. | |
dc.contributor.author | Abbastabar, H. | |
dc.contributor.author | Abreu, L.G. | |
dc.contributor.author | Abu-Gharbieh, E. | |
dc.contributor.author | Achappa, B. | |
dc.contributor.author | Adabi, M. | |
dc.contributor.author | Adal, T.G. | |
dc.contributor.author | Adegbosin, A.E. | |
dc.contributor.author | Adekanmbi, V. | |
dc.contributor.author | Adetokunboh, O.O. | |
dc.contributor.author | Agudelo-Botero, M. | |
dc.contributor.author | Ahinkorah, B.O. | |
dc.contributor.author | Ahmadi, K. | |
dc.contributor.author | Ahmed, M.B. | |
dc.contributor.author | Alhassan, R.K. | |
dc.contributor.author | Alipour, V. | |
dc.contributor.author | Almasi-Hashiani, A. | |
dc.contributor.author | Alvis-Guzman, N. | |
dc.contributor.author | Ancuceanu, R. | |
dc.contributor.author | Andrei, T. | |
dc.contributor.author | Anvari, D. | |
dc.contributor.author | Aqeel, M. | |
dc.contributor.author | Arabloo, J. | |
dc.contributor.author | Aremu, O. | |
dc.contributor.author | Asaad, M. | |
dc.contributor.author | Atnafu, D.D. | |
dc.contributor.author | Atreya, A. | |
dc.contributor.author | Paulina Ayala Quintanilla, B. | |
dc.contributor.author | Azari, S. | |
dc.contributor.author | B B, D. | |
dc.contributor.author | Baig, A.A. | |
dc.contributor.author | Banach, M. | |
dc.contributor.author | Bante, S.A. | |
dc.contributor.author | Barboza, M.A. | |
dc.contributor.author | Basu, S. | |
dc.contributor.author | Bedi, N. | |
dc.contributor.author | F Bejarano Ramirez, D. | |
dc.contributor.author | Bensenor, I.M. | |
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dc.contributor.author | Bhagavathula, A.S. | |
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dc.contributor.author | Bhardwaj, P. | |
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dc.contributor.author | Bhutta, Z.A. | |
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dc.contributor.author | Birlik, S.M. | |
dc.contributor.author | Bitew, Z.W. | |
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dc.contributor.author | Wickramasinghe, N.D. | |
dc.contributor.author | Yaya, S. | |
dc.contributor.author | Yip, P. | |
dc.contributor.author | Yonemoto, N. | |
dc.contributor.author | Yu, C. | |
dc.contributor.author | Yuce, D. | |
dc.contributor.author | Yusefzadeh, H. | |
dc.contributor.author | Zamanian, M. | |
dc.contributor.author | Zastrozhin, M.S. | |
dc.contributor.author | Zhang, Z.-J. | |
dc.contributor.author | Zhang, Y. | |
dc.contributor.author | Ziapour, A. | |
dc.contributor.author | Hay, S.I. | |
dc.contributor.author | Dwyer-Lindgren, L. | |
dc.date.accessioned | 2023-02-23T18:17:10Z | |
dc.date.available | 2023-02-23T18:17:10Z | |
dc.date.issued | 2021 | |
dc.description.abstract | Antecedentes: El virus de la inmunodeficiencia humana (VIH) sigue siendo una prioridad de salud pública en América Latina. Aunque la carga del VIH se concentra históricamente en las zonas urbanas y los grupos de alto riesgo, faltan estimaciones subnacionales que abarquen varios países y años. Esta escasez se debe en parte a que los sistemas de registro civil (RV) son incompletos y a los retos estadísticos relacionados con la estimación de las tasas de mortalidad en zonas con un bajo número de muertes por VIH. En este análisis, abordamos este vacío y proporcionamos estimaciones novedosas de la tasa de mortalidad por VIH y el número de muertes por VIH por grupo de edad, sexo y municipio en Brasil, Colombia, Costa Rica, Ecuador, Guatemala y México. Métodos Realizamos un estudio ecológico utilizando datos de RV entre 2000 y 2017, dependiendo de la disponibilidad de datos de cada país. Modelamos la mortalidad por VIH utilizando un modelo bayesiano de regresión de efectos mixtos espacialmente explícito que incorpora información previa sobre la exhaustividad de la RV. Calibramos nuestros resultados con el Global Burden of Disease Study 2017. Resultados Todos los países mostraron una diferencia de más de 40 veces en la mortalidad por VIH entre los municipios con la tasa de mortalidad por VIH estandarizada por edad más alta y más baja en el último año de estudio para los hombres, y una diferencia de más de 20 veces para las mujeres. A pesar de los descensos en la mortalidad por VIH a nivel nacional en todos los países -excepto Ecuador- a lo largo del periodo de estudio, encontramos una amplia variación en los cambios relativos en la mortalidad por VIH a nivel municipal y un aumento de la desigualdad relativa a lo largo del tiempo en todos los países. En los seis países incluidos en este análisis, el 50% o más de las muertes por VIH se concentraban en menos del 10% de los municipios en el último año de estudio. Además, los patrones nacionales de edad reflejaron cambios en la mortalidad hacia grupos de mayor edad: el grupo de edad mediana entre los fallecidos osciló entre 30 y 45 años a nivel de municipio en Brasil, Colombia y México en 2017. Conclusiones Nuestras estimaciones subnacionales de la mortalidad por VIH revelaron una variación espacial significativa y tendencias locales divergentes en la mortalidad por VIH a lo largo del tiempo y por edad. Este análisis proporciona un marco para incorporar datos e incertidumbre de sistemas de RV incompletos y puede ayudar a guiar una intervención de salud pública más precisa geográficamente para apoyar la atención relacionada con el VIH y reducir las muertes relacionadas con el VIH. | spa |
dc.description.abstractenglish | Background: Human immunodeficiency virus (HIV) remains a public health priority in Latin America. While the burden of HIV is historically concentrated in urban areas and high-risk groups, subnational estimates that cover multiple countries and years are missing. This paucity is partially due to incomplete vital registration (VR) systems and statistical challenges related to estimating mortality rates in areas with low numbers of HIV deaths. In this analysis, we address this gap and provide novel estimates of the HIV mortality rate and the number of HIV deaths by age group, sex, and municipality in Brazil, Colombia, Costa Rica, Ecuador, Guatemala, and Mexico. Methods We performed an ecological study using VR data ranging from 2000 to 2017, dependent on individual country data availability. We modeled HIV mortality using a Bayesian spatially explicit mixed-effects regression model that incorporates prior information on VR completeness. We calibrated our results to the Global Burden of Disease Study 2017. Results All countries displayed over a 40-fold difference in HIV mortality between municipalities with the highest and lowest age-standardized HIV mortality rate in the last year of study for men, and over a 20-fold difference for women. Despite decreases in national HIV mortality in all countries—apart from Ecuador—across the period of study, we found broad variation in relative changes in HIV mortality at the municipality level and increasing relative inequality over time in all countries. In all six countries included in this analysis, 50% or more HIV deaths were concentrated in fewer than 10% of municipalities in the latest year of study. In addition, national age patterns reflected shifts in mortality to older age groups—the median age group among decedents ranged from 30 to 45 years of age at the municipality level in Brazil, Colombia, and Mexico in 2017. Conclusions Our subnational estimates of HIV mortality revealed significant spatial variation and diverging local trends in HIV mortality over time and by age. This analysis provides a framework for incorporating data and uncertainty from incomplete VR systems and can help guide more geographically precise public health intervention to support HIV-related care and reduce HIV-related deaths. | eng |
dc.format.mimetype | application/pdf | |
dc.identifier.doi | https://doi.org/10.1186/s12916-020-01876-4 | |
dc.identifier.instname | instname:Universidad El Bosque | spa |
dc.identifier.issn | 1741-7015 | |
dc.identifier.reponame | reponame:Repositorio Institucional Universidad El Bosque | spa |
dc.identifier.repourl | repourl:https://repositorio.unbosque.edu.co | |
dc.identifier.uri | https://hdl.handle.net/20.500.12495/10052 | |
dc.language.iso | eng | |
dc.publisher | Springer Nature | spa |
dc.publisher.journal | BMC Medicine | spa |
dc.relation.ispartofseries | BMC Medicine, 1741-7015, 19, 1, 2021, 4 | spa |
dc.relation.uri | https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-020-01876-4 | |
dc.rights | Atribución 4.0 Internacional | * |
dc.rights.accessrights | https://purl.org/coar/access_right/c_abf2 | |
dc.rights.accessrights | info:eu-repo/semantics/openAccess | |
dc.rights.accessrights | Acceso abierto | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | VIH/SIDA | spa |
dc.subject | América Latina | spa |
dc.subject | Mortalidad por VIH | spa |
dc.subject | Registro civil | spa |
dc.subject | Estimación de áreas pequeñas | spa |
dc.subject | Cartografía | spa |
dc.subject | Estadísticas espaciales | spa |
dc.subject.keywords | HIV/AIDS | spa |
dc.subject.keywords | Latin America | spa |
dc.subject.keywords | HIV mortality | spa |
dc.subject.keywords | Vital registration | spa |
dc.subject.keywords | Small area estimation | spa |
dc.subject.keywords | Mapping | spa |
dc.subject.keywords | Spatial statistics | spa |
dc.title | Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems | spa |
dc.title.translated | Cartografía de la mortalidad subnacional por VIH en seis países latinoamericanos con sistemas de registro civil incompletos | spa |
dc.type.coar | https://purl.org/coar/resource_type/c_6501 | |
dc.type.coarversion | https://purl.org/coar/version/c_970fb48d4fbd8a85 | |
dc.type.driver | info:eu-repo/semantics/article | |
dc.type.hasversion | info:eu-repo/semantics/publishedVersion | |
dc.type.local | Artículo de revista |
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- Nombre:
- license.txt
- Tamaño:
- 1.71 KB
- Formato:
- Item-specific license agreed upon to submission
- Descripción: