Survey on hypoglycemia among insulin-treated patients with diabetes: the Colombian International operations hypoglycemia assessment tool population

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dc.contributor.authorGómez, Ana María
dc.contributor.authorChica, Luis G.
dc.contributor.authorBurbano, Álvaro F.
dc.contributor.authorVásquez, Esdras M.
dc.contributor.authorEscobar, Jorge A.
dc.contributor.authorArias, Paola M.
dc.contributor.authorMolina de Salazar, Dora Inés
dc.date.accessioned2020-05-11T19:15:24Z
dc.date.available2020-05-11T19:15:24Z
dc.date.issued2019
dc.description.abstractenglishIntroduction: The non-interventional International Operations Hypoglycemia Assessment Tool (IO-HAT) study assessed the incidence of hypoglycemia in patients with insulin-treated diabetes across nine countries, including a cohort of patients in Colombia. Materials and methods: Hypoglycemia incidence among patients with insulin-treated diabetes was assessed across 26 sites in Colombia. Hypoglycaemic events (any, nocturnal or severe) were reported in self-assessment questionnaires (SAQ) and patient diaries based on capillary blood glucose measurement or symptoms. Retrospective events (severe events 6 months before baseline and any event 4 weeks before baseline) were recorded in SAQ, Part 1, and prospective events (4 weeks from baseline) were recorded in SAQ, Part 2, and patient diaries. Differences in hypoglycemia incidence reported in the retrospective and prospective periods were assessed using two-sided tests. Results: Of the 664 patients assessed, 213 had type 1 diabetes (T1 D) and 451 had type 2 diabetes (T2 D). Nearly all patients experienced at least one hypoglycaemic event in the prospective period (97.1% T1 D; 93.3% T2 D). Rates of hypoglycemia (events per personyear, PPY) were higher prospectively than retrospectively for any hypoglycemia (T1 D: 121.6 vs. 83.2, p<0.001; T2 D: 28.1 vs. 24.6, p=0.127) and severe hypoglycemia (T1 D: 15.3 vs. 9.2, p=0.605; T2 D: 9.5 vs. 3.5 p=0.040). Conclusion: These results, the first from a patient-reported dataset on hypoglycemia in insulin-treated patients with diabetes in Colombia, show that patients reported higher rates of any hypoglycemia during the prospective period.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.7705/biomedica.4365
dc.identifier.issn0120-4157
dc.identifier.urihttps://hdl.handle.net/20.500.12495/2563
dc.language.isoeng
dc.publisherInstituto Nacional de Saludspa
dc.publisher.journalBiomedicaspa
dc.relation.ispartofseriesBiomedica, 0120-4157, Vol. 39, Nro. 3, 2019, p.1-23spa
dc.relation.urihttps://revistabiomedica.org/index.php/biomedica/article/view/4365
dc.rights.creativecommons2019
dc.rights.localAcceso cerradospa
dc.subject.decsMetaanálisisspa
dc.subject.decsInformes de casosspa
dc.subject.decsEnsayo clínicospa
dc.subject.keywordsDiabetes mellitusspa
dc.subject.keywordsHypoglycemiaspa
dc.subject.keywordsInsulin infusion systemsspa
dc.titleSurvey on hypoglycemia among insulin-treated patients with diabetes: the Colombian International operations hypoglycemia assessment tool populationspa
dc.title.translatedSurvey on hypoglycemia among insulin-treated patients with diabetes: the Colombian International operations hypoglycemia assessment tool populationspa
dc.typearticlespa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localartículospa

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