Seborrheic dermatitis: predisposing factors and ITS2 secondary structure for Malassezia phylogenic analysis

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dc.contributor.authorAmado, Yulien
dc.contributor.authorPatiño-Uzcátegui, Anelvi
dc.contributor.authorCepero de García, Maria C.
dc.contributor.authorTabima, Javier
dc.contributor.authorMotta Beltrán, Adriana
dc.contributor.authorCárdenas, Martha
dc.contributor.authorBernal, Adriana
dc.contributor.authorRestrepo, Silvia
dc.contributor.authorCelis, Adriana
dc.contributor.orcidMotta, Adriana [0000-0002-1924-1256]
dc.contributor.orcidMotta Beltrán, Adriana [0000-0002-1924-1256]
dc.contributor.orcidMotta Beltrán, Adriana [0000-0002-1924-1256]
dc.date.accessioned2020-07-28T14:33:20Z
dc.date.available2020-07-28T14:33:20Z
dc.date.issued2013
dc.description.abstractenglishSeborrheic dermatitis (SD) is a chronic, widespread skin condition, which is considered a multifactorial disease influenced, in part, by Malassezia spp. opportunistic activities, as well as various endogenous and exogenous factors. Malassezia species are lipophilic, lipid-dependent yeasts that are members of the normal mycobiota of the human skin. Their isolation from SD lesions varies around the world and the study of the relationship among factors such as gender, age, immunosuppressive condition of the patient and SD development, can lead to a better understanding of this disease. To elucidate the association of age and gender with the development of SD and to precisely determine the Malassezia species involved in the disease, samples were obtained from 134 individuals, including individuals without lesions, human immunodeficiency virus positive patients, individuals with seborrheic dermatitis, and HIV patients with seborrheic dermatitis. Malassezia spp. were identified by phenotypic and genotypic methods and a phylogenetic analysis was performed using Bayesian inference. This study revealed that age and gender are not predisposing factors for SD development, and that the most frequent species of Malassezia related to SD development among the Colombian population is M. restricta. We also report the isolation of M. yamatoensis for the first time in Colombia, and propose an ITS2 secondary structure from Malassezia taxa that can be used for precise identification and to establish more robust phylogenetic relationships.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.3109/13693786.2013.820001
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn1460-2709
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlhttps://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/3594
dc.language.isoeng
dc.publisherOxford University Pressspa
dc.publisher.journalMedical Mycologyspa
dc.relation.ispartofseriesMedical Mycology, 1460-2709, Vol. 51, No. 8, 2013 p. 868–875spa
dc.relation.urihttps://academic.oup.com/mmy/article/51/8/868/1000343
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.creativecommons2013-11
dc.rights.localAcceso abiertospa
dc.subject.keywordsSeborrheic dermatitis (SD)spa
dc.subject.keywordsMalasseziaspa
dc.subject.keywordsSecondary structure ITS2spa
dc.subject.keywordsHIVspa
dc.titleSeborrheic dermatitis: predisposing factors and ITS2 secondary structure for Malassezia phylogenic analysisspa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

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