dc.contributor.advisor	Cortes Ortiz, William Giovanni
dc.contributor.author	Tinoco Quitian, Sebastian Felipe
dc.contributor.author	Guerrero Fajardo, Carlos
dc.contributor.author	Suarez , Kevin Rene
dc.date.accessioned	2024-05-18T02:41:28Z
dc.date.available	2024-05-18T02:41:28Z
dc.date.issued	2024-04-25
dc.description.abstract	El 5-Hidorximetilfurfural o 5-HMF, es un compuesto que ha adquirido un gran valor para la industria sostenible en general, teniendo un gran impacto en la industria energética y farmacéutica, con una gran cantidad de aplicaciones. El siguiente trabajo evalúa la obtención del 5-HMF a partir de glucosa usando el ácido acético (10,0% v/v) como catalizador, evaluando las mejores condiciones encontradas en la búsqueda bibliográfica para los catalizadores ácidos, generando un sistema factorial 22 donde se evalúa el impacto de dos variables de reacción como son: la Temperatura (170 – 200°C) y el tiempo de reacción (60 – 120 min) sobre el Rendimiento. Se obtienen mediante el uso de un reactor tipo Batch y los resultados se cuantifican por HPLC y el uso de un patrón interno (Alcohol furfurílico). Los resultados generan valores de rendimiento de reacción, de 6,9%; 30,5%; 11,7% y 18,9%, siendo el mejor rendimiento el Ensayo 2 (200°C; 60 min). Confirmando que se obtiene 5-HMF y evidenciando la influencia de las variables de reacción sobre el ensayo, alterando la cantidad generada de 5-HMF y de otras sustancias relacionadas con la reacción, también se genera un análisis estadístico que confirma que las variables tienen gran influencia en el rendimiento de reacción
dc.description.abstractenglish	5-Hydorxymethylfurfural or 5-HMF, is a compound that has acquired great value for the sustainable industry in general, having a great impact on the energy and pharmaceutical industries, with a large number of applications. The following work evaluates the obtaining of 5-HMF from glucose using acetic acid (10.0% v/v) as a catalyst, evaluating the best conditions found in the biobibliographic search for acid catalysts, generating a 22 factorial system where The impact of two reaction variables such as: Temperature (170 – 200°C) and reaction time (60 – 120 min) on the Yield is evaluated. They are obtained by using a Batch type reactor and the results are quantified by HPLC and the use of an internal standard (furfuryl alcohol). The results generate reaction yield values of 6.9%; 30.5%; 11.7% and 18.9%, with the best performance being Test 2 (200°C; 60 min). Confirming that 5-HMF is obtained and evidencing the influence of the reaction variables on the test, altering the generated amount of 5-HMF and other substances related to the reaction, a statistical analysis is also generated that confirms that the variables have great influence on the reaction yield
dc.description.degreelevel	Pregrado	spa
dc.description.degreelevel	Químico Farmacéutico	spa
dc.format.mimetype	application/pdf
dc.identifier.instname	Universidad El Bosque	spa
dc.identifier.reponame	reponame:Repositorio Institucional Universidad El Bosque	spa
dc.identifier.repourl	repourl:https://repositorio.unbosque.edu.co
dc.identifier.uri	https://hdl.handle.net/20.500.12495/12148
dc.language.iso	es
dc.publisher.faculty	Facultad de Ciencias	spa
dc.publisher.grantor	Universidad El Bosque	spa
dc.publisher.program	Química Farmacéutica	spa
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dc.rights	Attribution 4.0 International	en
dc.rights.accessrights	info:eu-repo/semantics/openAccess
dc.rights.accessrights	https://purl.org/coar/access_right/c_abf2
dc.rights.local	Acceso abierto	spa
dc.rights.uri	http://creativecommons.org/licenses/by/4.0/
dc.subject	5-hidroximetilfurfural (5-hmf)
dc.subject	Ácido acético
dc.subject	Glucosa
dc.subject	Temperatura
dc.subject	Tiempo
dc.subject	Variables de reacción
dc.subject.ddc	615.19
dc.subject.keywords	5-hydroxymethylfurfural (5-hmf)
dc.subject.keywords	Acetic acid
dc.subject.keywords	Glucose
dc.subject.keywords	Temperature
dc.subject.keywords	Time
dc.subject.keywords	Reaction variables
dc.title	Obtención de 5-Hidroximetilfurfural (5-HMF), compuesto usado como excipiente en formulaciones líquidas o semisólidas, usando ácido acético como catalizador
dc.title.translated	Obtaining 5-Hydroxymethylfurfural (5-HMF), a compound used as an excipient in liquid or semi-solid formulations, using acetic acid as a catalyst
dc.type.coar	https://purl.org/coar/resource_type/c_7a1f
dc.type.coarversion	https://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.driver	info:eu-repo/semantics/bachelorThesis
dc.type.hasversion	info:eu-repo/semantics/acceptedVersion
dc.type.local	Tesis/Trabajo de grado - Monografía - Pregrado

Obtención de 5-Hidroximetilfurfural (5-HMF), compuesto usado como excipiente en formulaciones líquidas o semisólidas, usando ácido acético como catalizador

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