Abdominal adiposity correlates with adenotonsillectomy outcome in obese adolescents with severe obstructive sleep apnea

Vista sencilla de ítem
dc.contributor.authorNino, Gustavo
dc.contributor.authorGutierrez, Maria J.
dc.contributor.authorRavindra, Anjani
dc.contributor.authorNino, Cesar L.
dc.contributor.authorRodriguez-Martinez, Carlos E.
dc.date.accessioned2020-05-13T18:13:16Z
dc.date.available2020-05-13T18:13:16Z
dc.date.issued2012
dc.description.abstractenglishBackground. Obese adolescents with Obstructive Sleep Apnea (OSA) have a unique pathophysiology that combines adenotonsillar hypertrophy and increased visceral fat distribution. We hypothesized that in this population waist circumference (WC), as a clinical marker of abdominal fat distribution, correlates with the likelihood of response to AT. Methods. We conducted a retrospective cohort study of obese adolescents (BMI ≥ 97th percentile) that underwent AT for therapy of severe OSA (n = 21). We contrasted WC and covariates in a group of subjects that had complete resolution of severe OSA after AT (n = 7) with those obtained in subjects with residual OSA after AT (n = 14). Multivariate linear and logistic models were built to control possible confounders. Results. WC correlated negatively with a positive AT response in young adolescents and the percentage of improvement in obstructive apnea-hypopnea index (OAHI) after AT (P ≤ 0.01). Extended multivariate analysis demonstrated that the link between WC and AT response was independent of demographic variables, OSA severity, clinical upper airway assessment, obesity severity (BMI), and neck circumference (NC). Conclusion. The results suggest that in obese adolescents, abdominal fat distribution determined by WC may be a useful clinical predictor for residual OSA after AT.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1155/2012/351037
dc.identifier.issn2090-1844
dc.identifier.urihttps://hdl.handle.net/20.500.12495/2691
dc.language.isoeng
dc.publisherHindawi Pubspa
dc.publisher.journalPulmonary medicinespa
dc.relation.ispartofseriesPulmonary medicine, 2090-1844. Vol, 2012spa
dc.relation.urihttps://www.hindawi.com/journals/pm/2012/351037/
dc.rightsAttribution 4.0 International*
dc.rights.creativecommons2012
dc.rights.localAcceso abiertospa
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subject.decsObesidadspa
dc.subject.decsApnea obstructiva del sueñospa
dc.subject.decsAdolescentespa
dc.titleAbdominal adiposity correlates with adenotonsillectomy outcome in obese adolescents with severe obstructive sleep apneaspa
dc.typearticlespa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localartículospa

Archivos

Bloque original
Mostrando 1 - 1 de 1
Miniatura
Nombre:
Nino G., Gutierrez M.J., Ravindra A., Nino C.L., Rodriguez-Martinez C.E._2012.pdf
Tamaño:
1.27 MB
Formato:
Adobe Portable Document Format
Descripción:
Descargar
Bloque de licencias
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descripción:
Descargar

Colecciones

Artículos