Prevalence and distribution of peripheral musculoskeletal manifestations in spondyloarthritis including psoriatic arthritis: results of the worldwide, cross-sectional ASAS-PerSpA study

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dc.contributor.authorLópez Medina, Clementina
dc.contributor.authorMolto, Anna
dc.contributor.authorSieper, Joachim
dc.contributor.authorDuruöz, Tuncay
dc.contributor.authorKiltz, Uta
dc.contributor.authorElzorkany, Bassel
dc.contributor.authorHajjaj Hassouni, Najia
dc.contributor.authorBurgos Vargas, Ruben
dc.contributor.authorMaldonado Cocco, José
dc.contributor.authorZiade, Nelly
dc.contributor.authorGavali, Meghna
dc.contributor.authorNavarro Compan, Victoria
dc.contributor.authorLuo, Shue Fen
dc.contributor.authorMonti, Sara
dc.contributor.authorTae Jong, Kim
dc.contributor.authorKishimoto, Mitsumasa
dc.contributor.authorPimentel Santos, F M
dc.contributor.authorGu, Jieruo
dc.contributor.authorSchiotis, Ruxandra
dc.contributor.authorvan Gaalen, Floris A
dc.contributor.authorGeher, Pál
dc.contributor.authorMagrey, Marina
dc.contributor.authorIbáñez Vodnizza, Sebastián E
dc.contributor.authorBautista Molano, Wilson
dc.contributor.authorMaksymowych, Walter
dc.contributor.authorMachado, Pedro M
dc.contributor.authorLandewé, Robert
dc.contributor.authorvan der Heijde, Desirée
dc.contributor.authorDougados, Maxime
dc.contributor.orcidLópez Medina, Clementina [0000-0002-2309-5837]
dc.contributor.orcidMolto, Anna [0000-0003-2246-1986]
dc.contributor.orcidSieper, Joachim [0000-0003-0285-9890]
dc.contributor.orcidKiltz, Uta [0000-0001-5668-4497]
dc.contributor.orcidHajjaj Hassouni, Najia [0000-0003-0722-6822]
dc.contributor.orcidZiade, Nelly [0000-0002-4479-7678]
dc.contributor.orcidMonti, Sara [0000-0002-1800-6772]
dc.contributor.orcidvan Gaalen, Floris A [0000-0001-8448-7407]
dc.contributor.orcidIbáñez Vodnizza, Sebastián E [0000-0002-9577-3078]
dc.contributor.orcidBautista Molano, Wilson [0000-0003-0684-9542]
dc.contributor.orcidMachado, Pedro M [0000-0002-8411-7972]
dc.contributor.orcidvan der Heijde, Desirée [0000-0002-5781-158X]
dc.date.accessioned2021-05-21T21:25:57Z
dc.date.available2021-05-21T21:25:57Z
dc.date.issued2021-01-18
dc.description.abstractenglishObjectives To characterise peripheral musculoskeletal involvement in patients with spondyloarthritis (SpA) including psoriatic arthritis (PsA), across the world. Methods Cross-sectional study with 24 participating countries. Patients with a diagnosis of axial SpA (axSpA), peripheral SpA (pSpA) or PsA according to their rheumatologist were included. The investigators were asked which diagnosis out of a list of six (axSpA, PsA, pSpA, inflammatory bowel disease-associated SpA,reactive arthritis or juvenile SpA (Juv-SpA)) fitted the patient best. Peripheral manifestations (ie, peripheral joint disease, enthesitis, dactylitis and root joint disease), their localisation and treatments were evaluated. Results A total of 4465 patients were included (61% men, mean age 44.5 years) from four geographic areas: Latin merica (n=538), Europe plus North America (n=1677), Asia (n=975) and the Middle East plus North Africa (n=1275). Of those, 78% had ever suffered from at least one peripheral musculoskeletal manifestation; 57% had peripheral joint disease, 44% had enthesitis and 15% had dactylitis. Latin American had far more often peripheral joint disease (80%) than patients from other areas. Patients with PsA had predominantly upper limb and small joint involvement (52%). Hip and shoulder involvement was found in 34% of patients. The prevalence of enthesitis ranged between 41% in patients with axSpA and 65% in patients with Juv-SpA. Dactylitis was most frequent among patients with PsA (37%). Conclusion These results suggest that all peripheral features can be found in all subtypes of SpA, and that differences are quantitative rather than qualitative. In a high proportion of patients, axial and peripheral manifestations coincided. These findings reconfirm SpA clinical subtypes are descendants of the same underlying disease, called SpA.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1136/RMDOPEN-2020-001450
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn2056-5933
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/5890
dc.language.isoeng
dc.publisherBMJ Publishing Groupspa
dc.publisher.journalRMDspa
dc.relation.ispartofseriesRMD, 2056-5933, Vol. 7, Nro. 1, 2021spa
dc.relation.urihttps://rmdopen.bmj.com/content/rmdopen/7/1/e001450.full.pdf
dc.rightsAtribución-NoComercial 4.0 Internacional*
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.localAcceso abiertospa
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/*
dc.subject.keywordsAnkylosingspa
dc.subject.keywordsArthritisspa
dc.subject.keywordsJuvenilespa
dc.subject.keywordsPsoriaticspa
dc.subject.keywordsSpondylitisspa
dc.titlePrevalence and distribution of peripheral musculoskeletal manifestations in spondyloarthritis including psoriatic arthritis: results of the worldwide, cross-sectional ASAS-PerSpA studyspa
dc.title.translatedPrevalence and distribution of peripheral musculoskeletal manifestations in spondyloarthritis including psoriatic arthritis: results of the worldwide, cross-sectional ASAS-PerSpA studyspa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

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