Development of a RP-HPLC Method for Separating and Quantifying Muscimol in Different Developmental Stages of the Fungus Amanita muscaria

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dc.contributor.authorLeón Ávila, Emersón
dc.contributor.authorGuevara Pulido, James
dc.date.accessioned2021-02-26T15:01:12Z
dc.date.available2021-02-26T15:01:12Z
dc.description.abstractenglishA simple RP-HPLC method was designed for the quantification of muscimol (5-(aminomethyl)-isoxazol-3-ol) present in five aqueous extracts of Amanita muscaria each from a different developmental stage. Results show that the maximum concentration of muscimol (1,210 mg/ml) was found in the young mushroom stage of development. Moreover, it was also found that this concentration progressively decreases as the fungus ages. The developed method is a simple but effective method for the quantification of muscimol, a widely important metabolite for the pharmaceutical industry as a possible treatment for tardive dyskinesia and Parkinson’s disease.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1155/2020/8859998
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn2641-3051
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/5455
dc.language.isoeng
dc.publisherHindawispa
dc.publisher.journalJournal of Chemistryspa
dc.relation.ispartofseriesJournal of Chemistry, 2641-3051, Vol. 2020, p. 1-4spa
dc.relation.urihttps://www.hindawi.com/journals/jchem/2020/8859998/
dc.rightsAttribution 4.0 International*
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.creativecommons2020
dc.rights.localAcceso abiertospa
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subject.keywordsChromatographyspa
dc.subject.keywordsFungusspa
dc.subject.keywordsChemistryspa
dc.titleDevelopment of a RP-HPLC Method for Separating and Quantifying Muscimol in Different Developmental Stages of the Fungus Amanita muscariaspa
dc.title.translatedDevelopment of a RP-HPLC Method for Separating and Quantifying Muscimol in Different Developmental Stages of the Fungus Amanita muscariaspa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

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