Risk and protective factors for childhood asthma: what Is the evidence?

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dc.contributor.authorCastro-Rodriguez, Jose A.
dc.contributor.authorForno, Erick
dc.contributor.authorRodríguez-Martínez, Carlos E.
dc.contributor.authorCeledón, Juan Carlos
dc.date.accessioned2020-07-16T17:10:39Z
dc.date.available2020-07-16T17:10:39Z
dc.description.abstractenglishTo summarize the principal findings on risk and protective factors for childhood asthma, we retrieved systematic reviews on these topics in children (aged 1 to 18 years), up to January 2016, through MEDLINE, EMBASE, CINAHL, SCOPUS, and CDSR. A total of 227 studies were searched from databases. Among those, 41 systematic reviews (SRs) were included: 9 focused on prenatal factors, 5 on perinatal factors, and 27 on postnatal factors. Of these 41 SRs, 83% had good methodological quality, as determined by the Assess Systematic Reviews tool. After reviewing all evidence, parental asthma, prenatal environmental tobacco smoke, and prematurity (particularly very preterm birth) are well-established risk factors for childhood asthma. Current findings do suggest mild-to-moderate causal effects of certain modifiable behaviors or exposures during pregnancy (maternal weight gain or obesity, maternal use of antibiotics or paracetamol, and maternal stress), the perinatal period (birth by Caesarean delivery), or postnatal life (severe respiratory syncytial virus infection, overweight or obesity, indoor exposure to mold or fungi, and outdoor air pollution) on childhood asthma, but this suggestive evidence must be confirmed in interventional studies or (if interventions are not feasible) well-designed prospective studies.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.jaip.2016.05.003
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn2213-2201
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlhttps://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/3537
dc.language.isoeng
dc.publisherElsevierspa
dc.publisher.journalJournal of allergy and clinical immunology: in practicespa
dc.relation.ispartofseriesJournal of allergy and clinical immunology: in practice, 2213-2201, Vol. 4, Nro. 6, 2016, p, 1111-1122spa
dc.relation.urihttps://www.sciencedirect.com/science/article/abs/pii/S2213219816301398
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.creativecommons2016-11-01
dc.rights.localAcceso abiertospa
dc.subject.decsContaminación del airespa
dc.subject.decsLactancia maternaspa
dc.subject.decsReflujo gastroesofágicospa
dc.subject.keywordsAsthmaspa
dc.subject.keywordsWheezespa
dc.subject.keywordsChildrenspa
dc.titleRisk and protective factors for childhood asthma: what Is the evidence?spa
dc.title.translatedRisk and protective factors for childhood asthma: what Is the evidence?spa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

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