Aneurysmal subarachnoid hemorrhage associated with small aneurysms in smokers and women: A retrospective analysis

dc.contributor.authorFigueredo, Luisa F.
dc.contributor.authorPedraza Ciro, María Camila
dc.contributor.authorLopez McCormick, Juan Sebastian
dc.contributor.authorRueda Esteban, Roberto Javier
dc.contributor.authorMejía Cordovez, Juan Armando
dc.date.accessioned2019-09-12T22:05:04Z
dc.date.available2019-09-12T22:05:04Z
dc.date.issued2019
dc.description.abstractenglishBackground Previous studies have shown low rupture rates for small aneurysms (<10 mm), suggesting that the risk of treatment could exceed the benefits. However, evidence has changed, showing crescent rates of aneurysmal subarachnoid hemorrhage (aSAH) associated with small aneurysms. We report trends in size, localization, clinical characteristics, and outcomes of intracranial aneurysms (IAs). Methods In this retrospective study, a total of 200 clinical histories of patients diagnosed with IAs over an 8-year period were analyzed. Variables considered included age, sex, tobacco consumption, morphological characteristics of the aneurysm, complications, vasospasm, and mortality. Qualitative variables were assessed by measurements of absolute and relative frequency. Smoking behavior, aneurysm size, and aneurysm rupture (AR) were compared using 1-way analysis of variance. Categorical variables were analyzed using Pearson's χ2 test. Results The average age at presentation was 58 years. The average size of ruptured aneurysms in the general group was 2.5–7.5 mm, and AR was most common in women (76%) and in patients age 50–60 years (33%). The rate of vasospasm was 19%, and mortality was 37%. Smokers composed 32% of the cohort. Heavy smokers had a 57% rate of aSAH, with an average size of rupture of 5 mm. The most common location of aneurysms and AR was the AComA (33%). Conclusions Our results suggest increasing AR rates in aneurysms smaller than 10 mm. This trend is seen especially in individuals with heavy tobacco consumption and in women of perimenopausal age. Our findings show a tendency of AR in accordance with previous results and are expected to serve as basis for further research on aneurysm management.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.wnsx.2019.100038
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn2590-1397
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/1676
dc.language.isoeng
dc.publisherElsevierspa
dc.publisher.journalWorld Neurosurgery: Xspa
dc.relation.ispartofseriesWorld Neurosurgery: X, 2590-1397, Vol, 4, 2019, p. 1-8spa
dc.relation.urihttps://www.sciencedirect.com/science/article/pii/S2590139719300699?via%3Dihub#!
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf448
dc.rights.creativecommons2019
dc.rights.localAcceso abiertospa
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subject.decsUso de tabacospa
dc.subject.decsVasoespasmo cerebralspa
dc.subject.decsMortalidadspa
dc.subject.keywordsIntracranial aneurysmspa
dc.subject.keywordsMenopausalspa
dc.subject.keywordsSmall aneurysmspa
dc.titleAneurysmal subarachnoid hemorrhage associated with small aneurysms in smokers and women: A retrospective analysisspa
dc.typearticlespa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localartículospa

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