Efficacy of systemic antibiotics in nonsurgical periodontal therapy for diabetic subjects: a systematic review and meta‐analysis

Vista sencilla de ítem
dc.contributor.authorSouto, Maria Luisa
dc.contributor.authorRovai, Emanuel S.
dc.contributor.authorGanhito, Juliana A.
dc.contributor.authorHolzhausen, Marinella
dc.contributor.authorChambrone, Leandro
dc.contributor.authorPannuti, Cláudio M.
dc.contributor.orcidChambrone, Leandro [0000-0002-2838-1015]
dc.date.accessioned2020-05-18T06:25:41Z
dc.date.available2020-05-18T06:25:41Z
dc.date.issued2018
dc.description.abstractenglishObjectives To evaluate the effects of systemic antibiotics as adjuncts to nonsurgical periodontal treatment (NSPT), as opposed to using NSPT alone, on periodontal clinical parameters of diabetic patients with periodontitis. Materials and methods Randomised controlled trials with a follow‐up of 3 months or more, assessing the effects of NSPT in combination with antibiotics, in diabetic patients with periodontitis were included. Trials published up to August 2016 were identified from MEDLINE, EMBASE and LILACS databases. Meta‐analyses were conducted to determine changes in clinical attachment level (CAL), probing pocket depth (PPD), bleeding on probing (BOP) and gingival index (GI). Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) guidelines were followed in this review. Results Of the 164 papers potentially admissible to this systematic review, 15 articles on 11 randomised clinical trials were considered as eligible. The results of the meta‐analyses presented a modest additional benefit of 0.14 mm (95% confidence interval: 0.08–0.20) in reducing PPD but no further benefit in CAL gain. Conclusion When the data for all antibiotic protocols were considered together for the treatment of periodontitis patients with DM, a significant, albeit small, reduction of PPD and no improvement in CAL gain was observed. When the antibiotic protocols were analysed separately, the combination of amoxicillin plus metronidazole yielded the best results for PPD.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1111/idj.12384
dc.identifier.issn1875-595X
dc.identifier.urihttps://hdl.handle.net/20.500.12495/2902
dc.language.isoeng
dc.publisherWileyspa
dc.publisher.journalInternational Dental Journalspa
dc.relation.ispartofseriesInternational Dental Journal, 1875-595X, Vol 68, Num 4, 2018, pag 207-220spa
dc.relation.urihttps://onlinelibrary.wiley.com/doi/full/10.1111/idj.12384
dc.rights.creativecommons2018
dc.rights.localAcceso cerradospa
dc.subject.decsEvaluación de medicamentosspa
dc.subject.decsAntiinfecciososspa
dc.subject.decsEnfermedades periodontalesspa
dc.subject.keywordsDiabetes mellitusspa
dc.subject.keywordsPeriodontal diseasesspa
dc.subject.keywordsAnti‐infective agentsspa
dc.subject.keywordsRoot planingspa
dc.subject.keywordsSystematic reviewspa
dc.titleEfficacy of systemic antibiotics in nonsurgical periodontal therapy for diabetic subjects: a systematic review and meta‐analysisspa
dc.title.translatedEfficacy of systemic antibiotics in nonsurgical periodontal therapy for diabetic subjects: a systematic review and meta‐analysisspa
dc.typearticlespa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localartículospa

Archivos

Bloque original
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
Souto, Maria Luisa..pdf
Tamaño:
1.81 MB
Formato:
Adobe Portable Document Format
Descripción:
Descargar
Bloque de licencias
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descripción:
Descargar

Colecciones

Artículos