Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

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dc.contributor.authorVos, Theo
dc.contributor.authorLim, Stephen S.
dc.contributor.authorAbbafati, Cristiana
dc.contributor.authorAbbas, Kaja M.
dc.contributor.authorAbbasi, Mohammad
dc.contributor.authorAbbasifard, Mitra
dc.contributor.authorAbbasi Kangevari, Mohsen
dc.contributor.authorAbbastabar, Hedayat
dc.contributor.authorAbd Allah, Foad
dc.contributor.authorAbdelalim, Ahmed
dc.contributor.authorAbdollahi, Mohammad
dc.contributor.authorAbdollahpour, Ibrahim
dc.contributor.authorAbolhassani, Hassan
dc.contributor.authorAboyans, Victor
dc.contributor.authorAbrams, Elissa M.
dc.contributor.authorAbreu, Lucas Guimarães
dc.contributor.authorAbrigo, Michael R. M.
dc.contributor.authorAbu Raddad, Laith Jamal
dc.contributor.authorAbushouk, Abdelrahman I.
dc.contributor.authorAcebedo, Alyssa
dc.contributor.authorAckerman, Ilana N.
dc.contributor.authorAdabi, Maryam
dc.contributor.authorAdamu, Abdu A.
dc.contributor.authorAdebayo, Oladimeji M.
dc.contributor.authorAdekanmbi, Victor
dc.contributor.authorAdelson, Jaimie D.
dc.contributor.authorAdetokunboh, Olatunji O.
dc.contributor.authorAdham, Davoud
dc.contributor.authorAfshari, Mahdi
dc.contributor.authorAfshin, Ashkan
dc.contributor.authorAgardh, Emilie E.
dc.contributor.authorAgarwal, Gina
dc.contributor.authorAgesa, Kareha M.
dc.contributor.authorAghaali, Mohammad
dc.contributor.authorAghamir, Seyed Mohammad Kazem
dc.contributor.authorAgrawal, Anurag
dc.contributor.authorAhmad, Tauseef
dc.contributor.authorAhmadi, Alireza
dc.contributor.authorAhmadi, Mehdi
dc.contributor.authorAhmadieh, Hamid
dc.contributor.authorAhmadpour, Ehsan
dc.contributor.authorAkalu, Temesgen Yihunie
dc.contributor.authorAkinyemi, Rufus Olusola
dc.contributor.authorAkinyemiju, Tomi
dc.contributor.authorAkombi, Blessing
dc.contributor.authorAl Aly, Ziyad
dc.contributor.authorAlam, Khurshid
dc.contributor.authorAlam, Noore
dc.contributor.authorAlam, Samiah
dc.contributor.authorAlam, Tahiya
dc.contributor.authorAlanzi, Turki M.
dc.contributor.authorAlbertson, Samuel B.
dc.contributor.authorAlcalde Rabanal, Jacqueline Elizabeth
dc.contributor.authorAlema, Niguse Meles
dc.contributor.authorAli, Muhammad
dc.contributor.authorAli, Saqib
dc.contributor.authorAlicandro, Gianfranco
dc.contributor.authorAlijanzadeh, Mehran
dc.contributor.authorAlinia, Cyrus
dc.contributor.authorAlipour, Vahid
dc.contributor.authorAljunid, Syed Mohamed
dc.contributor.authorAlla, François
dc.contributor.authorAllebeck, Peter
dc.contributor.authorAlmasi Hashiani, Amir
dc.contributor.authorAlonso, Jordi
dc.contributor.authorAl Raddadi, Rajaa M.
dc.contributor.authorAltirkawi, Khalid A.
dc.contributor.authorAlvis Guzman, Nelson
dc.contributor.authorAlvis Zakzuk, Nelson J.
dc.contributor.authorAmini, Saeed
dc.contributor.authorAmini Rarani, Mostafa
dc.contributor.authorAminorroaya, Arya
dc.contributor.authorAmiri, Fatemeh
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dc.contributor.authorAmugsi, Dickson A.
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dc.contributor.authorAndrei, Catalina Liliana
dc.contributor.authorAndrei, Tudorel
dc.contributor.authorAnjomshoa, Mina
dc.contributor.authorAnsari, Fereshteh
dc.contributor.authorAnsari, Iman
dc.contributor.authorAnsari Moghaddam, Alireza
dc.contributor.authorAntonio, Carl Abelardo T.
dc.contributor.authorAntony, Catherine M.
dc.contributor.authorAntriyandarti, Ernoiz
dc.contributor.authorAnvari, Davood
dc.contributor.authorAnwer, Razique
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dc.contributor.authorÄrnlöv, Johan
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dc.contributor.authorArzani, Afsaneh
dc.contributor.authorAsadi Aliabadi, Mehran
dc.contributor.authorAsadi Pooya, Ali A.
dc.contributor.authorAsghari, Babak
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dc.contributor.authorAtnafu, Desta Debalkie
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dc.contributor.authorAusloos, Floriane
dc.contributor.authorAusloos, Marcel
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dc.contributor.authorAyano, Getinet
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dc.contributor.authorAynalem, Yared Asmare
dc.contributor.authorAzari, Samad
dc.contributor.authorAzarian, Ghasem
dc.contributor.authorAzene, Zelalem Nigussie
dc.contributor.authorBabaee, Ebrahim
dc.contributor.authorBadawi, Alaa
dc.contributor.authorBagherzadeh, Mojtaba
dc.contributor.authorBakhshaei, Mohammad Hossein
dc.contributor.authorBakhtiari, Ahad
dc.contributor.authorBalakrishnan, Senthilkumar
dc.contributor.authorBalalla, Shivanthi
dc.contributor.authorBalassyano, Shelly
dc.contributor.authorBanach, Maciej
dc.contributor.authorBanik, Palash Chandra
dc.contributor.authorBannick, Marlena S.
dc.contributor.authorBante, Agegnehu Bante
dc.contributor.authorBaraki, Adhanom Gebreegziabher
dc.contributor.authorBarboza, Miguel A.
dc.contributor.authorBarker Collo, Suzanne Lyn
dc.contributor.authorBarthelemy, Celine M.
dc.contributor.authorBarua, Lingkan
dc.contributor.authorBarzegar, Akbar
dc.contributor.authorBasu, Sanjay
dc.contributor.authorBaune, Bernhard T.
dc.contributor.authorBayati, Mohsen
dc.contributor.authorBazmandegan, Gholamreza
dc.contributor.authorBedi, Neeraj
dc.contributor.authorBeghi, Ettore
dc.contributor.authorBéjot, Yannick
dc.contributor.authorBello, Aminu K.|
dc.contributor.authorBender, Rose G.
dc.contributor.authorBennett, Derrick A.
dc.contributor.authorBennitt, Fiona B.
dc.contributor.authorBensenor, Isabela M.
dc.contributor.authorBenziger, Catherine P.
dc.contributor.authorBerhe, Kidanemaryam
dc.contributor.authorBernabe, Eduardo
dc.contributor.authorBertolacci, Gregory J.
dc.contributor.authorBhageerathy, Reshmi
dc.contributor.authorBhala, Neeraj
dc.contributor.authorBhandari, Dinesh
dc.contributor.authorBhardwaj, Pankaj
dc.contributor.authorBhattacharyya, Krittika
dc.contributor.authorBhutta, Zulfiqar A.
dc.contributor.authorBibi, Sadia
dc.contributor.authorBiehl, Molly H.
dc.contributor.authorBikbov, Boris
dc.contributor.authorBin Sayeed, Muhammad Shahdaat
dc.contributor.authorBiondi, Antonio
dc.contributor.authorBirihane, Binyam Minuye
dc.contributor.authorBisanzio, Donal
dc.contributor.authorBisignano, Catherine
dc.contributor.authorBiswas, Raaj Kishore
dc.contributor.authorBohlouli, Somayeh
dc.contributor.authorBohluli, Mehdi
dc.contributor.authorBolla, Srinivasa Rao Rao
dc.contributor.authorBoloor, Archith
dc.contributor.authorBoon Dooley, Alexandra S.
dc.contributor.authorBorges, Guilherme
dc.contributor.authorBorzì, Antonio Maria
dc.contributor.authorBourne, Rupert
dc.contributor.authorBrady, Oliver J.
dc.contributor.authorBrauer, Michael
dc.contributor.authorBrayne, Carol
dc.contributor.authorBreitborde, Nicholas J. K.
dc.contributor.authorBrenner, Hermann
dc.contributor.authorBriant, Paul Svitil
dc.contributor.authorBriggs, Andrew M.
dc.contributor.authorBriko, Nikolay Ivanovich
dc.contributor.authorBritton, Gabrielle B.
dc.contributor.authorBryazka, Dana
dc.contributor.authorBuchbinder, Rachelle
dc.contributor.authorBumgarner, Blair R.
dc.contributor.authorBusse, Reinhard
dc.contributor.authorButt, Zahid A.
dc.contributor.authorCaetano dos Santos, Florentino Luciano
dc.contributor.authorCámera, Luis LA Alberto
dc.contributor.authorCampos Nonato, Ismael R.
dc.contributor.authorCar, Josip
dc.contributor.authorCárdenas, Rosario
dc.contributor.authorCarreras, Giulia
dc.contributor.authorCarrero, Juan J.
dc.contributor.authorCarvalho, Felix
dc.contributor.authorCastaldelli Maia, Joao Mauricio
dc.contributor.authorCastañeda Orjuela, Carlos A.
dc.contributor.authorCastelpietra, Giulio
dc.contributor.authorCastle, Chris D.
dc.contributor.authorCastro, Franz
dc.contributor.authorCatalá López, Ferrán
dc.contributor.authorCausey, Kate
dc.contributor.authorCederroth, Christopher R.
dc.contributor.authorCercy, Kelly M.
dc.contributor.authorCerin, Ester
dc.contributor.authorChandan, Joht Singh
dc.contributor.authorChang, Alex R.
dc.contributor.authorCharlson, Fiona J.
dc.contributor.authorChattu, Vijay Kumar
dc.contributor.authorChaturvedi, Sarika
dc.contributor.authorChimed Ochir, Odgerel
dc.contributor.authorChin, Ken Lee
dc.contributor.authorCho, Daniel Youngwhan
dc.contributor.authorChristensen, Hanne
dc.contributor.authorChu, Dinh Toi
dc.contributor.authorChung, Michael T.
dc.contributor.authorCicuttini, Flavia M.
dc.contributor.authorCiobanu, Liliana G.
dc.contributor.authorCirillo, Massimo
dc.contributor.authorCollins, Emma L.
dc.contributor.authorCompton, Kelly
dc.contributor.authorConti, Sara
dc.contributor.authorCortesi, Paolo Angelo
dc.contributor.authorCosta, Vera Marisa
dc.contributor.authorCousin, Ewerton
dc.contributor.authorCowden, Richard G.
dc.contributor.authorCowie, Benjamin C.
dc.contributor.authorCromwell, Elizabeth A.
dc.contributor.authorCross, Di H.
dc.contributor.authorCrowe, Christopher Stephen
dc.contributor.authorCruz, Jessica A.
dc.contributor.authorCunningham, Matthew
dc.contributor.authorDahlawi, Saad M. A.
dc.contributor.authorDamiani, Giovanni
dc.contributor.authorDandona, Lalit
dc.contributor.authorDandona, Rakhi
dc.contributor.authorDarwesh, Aso Mohammad
dc.contributor.authorDaryani, Ahmad
dc.contributor.authorDas Gupta, Rajat
dc.contributor.authordas Neves, José
dc.contributor.authorDávila Cervantes, Claudio Alberto
dc.contributor.authorDavletov, Kairat
dc.contributor.authorDe Leo, Diego
dc.contributor.authorDean, Frances E.
dc.contributor.authorDeCleene, Nicole K.
dc.contributor.authorDeen, Amanda
dc.contributor.authorDegenhardt, Louisa
dc.contributor.authorDellavalle, Robert Paul
dc.contributor.authorDemeke, Feleke Mekonnen
dc.contributor.authorDemsie, Desalegn Getnet
dc.contributor.authorDenova Gutiérrez, Edgar
dc.contributor.authorDereje, Nebiyu Dereje
dc.contributor.authorDervenis, Nikolaos
dc.contributor.authorDesai, Rupak
dc.contributor.authorDesalew, Assefa
dc.contributor.authorDessie, Getenet Ayalew
dc.contributor.authorDharmaratne, Samath Dhamminda
dc.contributor.authorDhungana, Govinda Prasad
dc.contributor.authorDianatinasab, Mostafa
dc.contributor.authorDiaz, Daniel
dc.contributor.authorDibaji Forooshani, Zahra Sadat
dc.contributor.authorDingels, Zachary V.
dc.contributor.authorDirac, M. Ashworth
dc.contributor.authorDjalalinia, Shirin
dc.contributor.authorDo, Hoa Thi
dc.contributor.authorDokova, Klara
dc.contributor.authorDorostkar, Fariba
dc.contributor.authorDoshi, Chirag P.
dc.contributor.authorDoshmangir, Leila
dc.contributor.authorDouiri, Abdel
dc.contributor.authorDoxey, Matthew C.
dc.contributor.authorDriscoll, Tim Robert
dc.contributor.authorDunachie, Susanna J.
dc.contributor.authorDuncan, Bruce B.
dc.contributor.authorDuraes, Andre Rodrigues
dc.contributor.authorEagan, Arielle Wilder
dc.contributor.authorEbrahimi Kalan, Mohammad
dc.contributor.authorEdvardsson, David
dc.contributor.authorEhrlich, Joshua R.
dc.contributor.authorEl Nahas, Nevine
dc.contributor.authorEl Sayed, Iman
dc.contributor.authorEl Tantawi, Maha
dc.contributor.authorElbarazi, Iffat
dc.contributor.authorElgendy, Islam Y.
dc.contributor.authorElhabashy, Hala Rashad
dc.contributor.authorEl Jaafary, Shaimaa I.
dc.contributor.authorElyazar, Iqbal RF
dc.contributor.authorEmamian, Mohammad Hassan
dc.contributor.authorEmmons Bell, Sophia
dc.contributor.authorErskine, Holly E.
dc.contributor.authorEshrati, Babak
dc.contributor.authorEskandarieh, Sharareh
dc.contributor.authorEsmaeilnejad, Saman
dc.contributor.authorEsmaeilzadeh, Firooz
dc.contributor.authorEsteghamati, Alireza
dc.contributor.authorEstep, Kara
dc.contributor.authorEtemadi, Arash
dc.contributor.authorEtisso, Atkilt Esaiyas
dc.contributor.authorFarahmand, Mohammad
dc.contributor.authorFaraj, Anwar
dc.contributor.authorFareed, Mohammad
dc.contributor.authorFaridnia, Roghiyeh
dc.contributor.authorFarinha, Carla Sofia e Sá
dc.contributor.authorFarioli, Andrea
dc.contributor.authorFaro, Andre
dc.contributor.authorFaruque, Mithila
dc.contributor.authorFarzadfar, Farshad
dc.contributor.authorFattahi, Nazir
dc.contributor.authorFazlzadeh, Mehdi
dc.contributor.authorFeigin, Valery L.
dc.contributor.authorFeldman, Rachel
dc.contributor.authorFereshtehnejad, Seyed Mohammad
dc.contributor.authorFernandes, Eduarda
dc.contributor.authorFerrari, Alize J.
dc.contributor.authorFerreira, Manuela L.
dc.contributor.authorFilip, Irina
dc.contributor.authorFischer, Florian
dc.contributor.authorFisher, James L.
dc.contributor.authorFitzgerald, Ryan
dc.contributor.authorFlohr, Carsten
dc.contributor.authorFlor, Luisa Sorio
dc.contributor.authorFoigt, Nataliya A.
dc.contributor.authorFolayan, Morenike Oluwatoyin
dc.contributor.authorForce, Lisa M.
dc.contributor.authorFornari, Carla
dc.contributor.authorForoutan, Masoud
dc.contributor.authorFox, Jack T.
dc.contributor.authorFreitas, Marisa
dc.contributor.authorFu, Weijia
dc.contributor.authorFukumoto, Takeshi
dc.contributor.authorFurtado, João M.
dc.contributor.authorGad, Mohamed M.
dc.contributor.authorGakidou, Emmanuela
dc.contributor.authorGalles, Natalie C.
dc.contributor.authorGallus, Silvano
dc.contributor.authorGamkrelidze, Amiran
dc.contributor.authorGarcia Basteiro, Alberto L.
dc.contributor.authorGardner, William M.
dc.contributor.authorGeberemariyam, Biniyam Sahiledengle
dc.contributor.authorGebrehiwot, Abiyu Mekonnen
dc.contributor.authorGebremedhin, Ketema Bizuwork
dc.contributor.authorGebreslassie, Assefa Ayalew Ayalew Ayalew
dc.contributor.authorGershberg Hayoon, Anna
dc.contributor.authorGething, Peter W.
dc.contributor.authorGhadimi, Maryam
dc.contributor.authorGhadiri, Keyghobad
dc.contributor.authorGhafourifard, Mansour
dc.contributor.authorGhajar, Alireza
dc.contributor.authorGhamari, Farhad
dc.contributor.authorGhashghaee, Ahmad
dc.contributor.authorGhiasvand, Hesam
dc.contributor.authorGhith, Nermin
dc.contributor.authorGholamian, Asadollah
dc.contributor.authorGilani, Syed Amir
dc.contributor.authorGill, Paramjit Singh
dc.contributor.authorGitimoghaddam, Mojgan
dc.contributor.authorGiussani, Giorgia
dc.contributor.authorGoli, Srinivas
dc.contributor.authorGomez, Ricardo Santiago
dc.contributor.authorGopalani, Sameer Vali
dc.contributor.authorGorini, Giuseppe
dc.contributor.authorGorman, Taren M.
dc.contributor.authorGottlich, Harrison Chase
dc.contributor.authorGoudarzi, Houman
dc.contributor.authorGoulart, Alessandra C.
dc.contributor.authorGoulart, Bárbara Niegia Garcia
dc.contributor.authorGrada, Ayman
dc.contributor.authorGrivna, Michal
dc.contributor.authorGrosso, Giuseppe
dc.contributor.authorGubari, Mohammed Ibrahim Mohialdeen
dc.contributor.authorGugnani, Harish Chander
dc.contributor.authorGuimaraes, Andre Luiz Sena
dc.contributor.authorGuimarães, Rafael Alves
dc.contributor.authorGuled, Rashid Abdi
dc.contributor.authorGuo, Gaorui
dc.contributor.authorGuo, Yuming
dc.contributor.authorGupta, Rajeev
dc.contributor.authorHaagsma, Juanita A.
dc.contributor.authorHaddock, Beatrix
dc.contributor.authorHafezi Nejad, Nima
dc.contributor.authorHafiz, Abdul
dc.contributor.authorHagins, Hailey
dc.contributor.authorHaile, Lydia M.
dc.contributor.authorHall, Brian J.
dc.contributor.authorHalvaei, Iman
dc.contributor.authorHamadeh, Randah R.
dc.contributor.authorHamagharib Abdullah, Kanaan
dc.contributor.authorHamilton, Erin B.
dc.contributor.authorHan, Chieh
dc.contributor.authorHan, Hannah
dc.contributor.authorHankey, Graeme J.
dc.contributor.authorHaro, Josep Maria
dc.contributor.authorHarvey, James D.
dc.contributor.authorHasaballah, Ahmed I.
dc.contributor.authorHasanzadeh, Amir
dc.contributor.authorHashemian, Maryam
dc.contributor.authorHassanipour, Soheil
dc.contributor.authorHassankhani, Hadi
dc.contributor.authorHavmoeller, Rasmus J.
dc.contributor.authorHay, Roderick J.
dc.contributor.authorHay, Simon I.
dc.contributor.authorHayat, Khezar
dc.contributor.authorHeidari, Behnam
dc.contributor.authorHeidari, Golnaz
dc.contributor.authorHeidari Soureshjani, Reza
dc.contributor.authorHendrie, Delia
dc.contributor.authorHenrikson, Hannah J.
dc.contributor.authorHenry, Nathaniel J.
dc.contributor.authorHerteliu, Claudiu
dc.contributor.authorHeydarpour, Fatemeh
dc.contributor.authorHird, Thomas R.
dc.contributor.authorHoek, Hans W.
dc.contributor.authorHole, Michael K.
dc.contributor.authorHolla, Ramesh
dc.contributor.authorHoogar, Praveen
dc.contributor.authorHosgood, H. Dean
dc.contributor.authorHosseinzadeh, Mehdi
dc.contributor.authorHostiuc, Mihaela
dc.contributor.authorHostiuc, Sorin
dc.contributor.authorHouseh, Mowafa
dc.contributor.authorHoy, Damian G.
dc.contributor.authorHsairi, Mohamed
dc.contributor.authorHsieh, Vivian Chia rong
dc.contributor.authorHu, Guoqing
dc.contributor.authorHuda, Tanvir M.
dc.contributor.authorHugo, Fernando N.
dc.contributor.authorHuynh, Chantal K.
dc.contributor.authorHwang, Bing Fang
dc.contributor.authorIannucci, Vincent C.
dc.contributor.authorIbitoye, Segun Emmanuel
dc.contributor.authorIkuta, Kevin S.
dc.contributor.authorIlesanmi, Olayinka Stephen
dc.contributor.authorIlic, Irena M.
dc.contributor.authorIlic, Milena D.
dc.contributor.authorInbaraj, Leeberk Raja
dc.contributor.authorIppolito, Helen
dc.contributor.authorIrvani, Seyed Sina Naghibi
dc.contributor.authorIslam, M. Mofizul
dc.contributor.authorIslam, MdMohaimenul
dc.contributor.authorIslam, Sheikh Mohammed Shariful
dc.contributor.authorIslami, Farhad
dc.contributor.authorIso, Hiroyasu
dc.contributor.authorIvers, Rebecca Q.
dc.contributor.authorIwu, Chidozie C. D.
dc.contributor.authorIyamu, Ihoghosa Osamuyi
dc.contributor.authorJaafari, Jalil
dc.contributor.authorJacobsen, Kathryn H.
dc.contributor.authorJadidi Niaragh, Farhad
dc.contributor.authorJafari, Hussain
dc.contributor.authorJafarinia, Morteza
dc.contributor.authorJahagirdar, Deepa
dc.contributor.authorJahani, Mohammad Ali
dc.contributor.authorJahanmehr, Nader
dc.contributor.authorJakovljevic, Mihajlo
dc.contributor.authorJalali, Amir
dc.contributor.authorJalilian, Farzad
dc.contributor.authorJames, Spencer L.
dc.contributor.authorJanjani, Hosna
dc.contributor.authorJanodia, Manthan Dilipkumar
dc.contributor.authorJayatilleke, Achala Upendra
dc.contributor.authorJeemon, Panniyammakal
dc.contributor.authorJenabi, Ensiyeh
dc.contributor.authorJha, Ravi Prakash
dc.contributor.authorJha, Vivekanand
dc.contributor.authorJi, John S.
dc.contributor.authorJia, Peng
dc.contributor.authorJohn, Oommen
dc.contributor.authorJohn Akinola, Yetunde O.
dc.contributor.authorJohnson, Catherine Owens
dc.contributor.authorJohnson, Sarah Charlotte
dc.contributor.authorJonas, Jost B.
dc.contributor.authorJoo, Tamas
dc.contributor.authorJoshi, Ankur
dc.contributor.authorJozwiak, Jacek Jerzy
dc.contributor.authorJürisson, Mikk
dc.contributor.authorKabir, Ali
dc.contributor.authorKabir, Zubair
dc.contributor.authorKalani, Hamed
dc.contributor.authorKalani, Rizwan
dc.contributor.authorKalankesh, Leila R.
dc.contributor.authorKalhor, Rohollah
dc.contributor.authorKamiab, Zahra
dc.contributor.authorKanchan, Tanuj
dc.contributor.authorKarami Matin, Behzad
dc.contributor.authorKarch, André
dc.contributor.authorKarim, Mohd Anisul
dc.contributor.authorKarimi, Salah Eddin
dc.contributor.authorKassa, Getachew Mullu
dc.contributor.authorKassebaum, Nicholas J.
dc.contributor.authorKatikireddi, Srinivasa Vittal
dc.contributor.authorKawakami, Norito
dc.contributor.authorKayode, Gbenga A.
dc.contributor.authorKeddie, Suzanne H.
dc.contributor.authorKeller, Cathleen
dc.contributor.authorKereselidze, Maia
dc.contributor.authorKhafaie, Morteza Abdullatif
dc.contributor.authorKhalid, Nauman
dc.contributor.authorKhan, Maseer
dc.contributor.authorKhatab, Khaled
dc.contributor.authorKhater, Mona M.
dc.contributor.authorKhatib, Mahalaqua Nazli
dc.contributor.authorKhayamzadeh, Maryam
dc.contributor.authorKhodayari, Mohammad Taghi
dc.contributor.authorKhundkar, Roba
dc.contributor.authorKianipour, Neda
dc.contributor.authorKieling, Christian
dc.contributor.authorKim, Daniel
dc.contributor.authorKim, Young Eun
dc.contributor.authorKim, Yun Jin
dc.contributor.authorKimokoti, Ruth W.
dc.contributor.authorKisa, Adnan
dc.contributor.authorKisa, Sezer
dc.contributor.authorKissimova Skarbek, Katarzyna
dc.contributor.authorKivimäki, Mika
dc.contributor.authorKneib, Cameron J.
dc.contributor.authorKnudsen, Ann Kristin Skrindo
dc.contributor.authorKocarnik, Jonathan M.
dc.contributor.authorKolola, Tufa
dc.contributor.authorKopec, Jacek A.
dc.contributor.authorKosen, Soewarta
dc.contributor.authorKoul, Parvaiz A.
dc.contributor.authorKoyanagi, Ai
dc.contributor.authorKravchenko, Michael A.
dc.contributor.authorKrishan, Kewal
dc.contributor.authorKrohn, Kris J.
dc.contributor.authorKuate Defo, Barthelemy
dc.contributor.authorKucuk Bicer, Burcu
dc.contributor.authorKumar, G. Anil
dc.contributor.authorKumar, Manasi
dc.contributor.authorKumar, Pushpendra
dc.contributor.authorKumar, Vivek
dc.contributor.authorKumaresh, Girikumar
dc.contributor.authorKurmi, Om P.
dc.contributor.authorKusuma, Dian
dc.contributor.authorKyu, Hmwe Hmwe
dc.contributor.authorLa Vecchia, Carlo
dc.contributor.authorLacey, Ben
dc.contributor.authorLal, Dharmesh Kumar
dc.contributor.authorLalloo, Ratilal
dc.contributor.authorLam, Jennifer O.
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dc.date.accessioned2021-03-01T15:37:16Z
dc.date.available2021-03-01T15:37:16Z
dc.description.abstractenglishBackground In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive and collectively exhaustive list of diseases and injuries. Methods GBD estimates incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) due to 369 diseases and injuries, for two sexes, and for 204 countries and territories. Input data were extracted from censuses, household surveys, civil registration and vital statistics, disease registries, health service use, air pollution monitors, satellite imaging, disease notifications, and other sources. Cause-specific death rates and cause fractions were calculated using the Cause of Death Ensemble model and spatiotemporal Gaussian process regression. Cause-specific deaths were adjusted to match the total all-cause deaths calculated as part of the GBD population, fertility, and mortality estimates. Deaths were multiplied by standard life expectancy at each age to calculate YLLs. A Bayesian meta-regression modelling tool, DisMod-MR 2.1, was used to ensure consistency between incidence, prevalence, remission, excess mortality, and cause-specific mortality for most causes. Prevalence estimates were multiplied by disability weights for mutually exclusive sequelae of diseases and injuries to calculate YLDs. We considered results in the context of the Socio-demographic Index (SDI), a composite indicator of income per capita, years of schooling, and fertility rate in females younger than 25 years. Uncertainty intervals (UIs) were generated for every metric using the 25th and 975th ordered 1000 draw values of the posterior distribution. Findings Global health has steadily improved over the past 30 years as measured by age-standardised DALY rates. After taking into account population growth and ageing, the absolute number of DALYs has remained stable. Since 2010, the pace of decline in global age-standardised DALY rates has accelerated in age groups younger than 50 years compared with the 1990–2010 time period, with the greatest annualised rate of decline occurring in the 0–9-year age group. Six infectious diseases were among the top ten causes of DALYs in children younger than 10 years in 2019: lower respiratory infections (ranked second), diarrhoeal diseases (third), malaria (fifth), meningitis (sixth), whooping cough (ninth), and sexually transmitted infections (which, in this age group, is fully accounted for by congenital syphilis; ranked tenth). In adolescents aged 10–24 years, three injury causes were among the top causes of DALYs: road injuries (ranked first), self-harm (third), and interpersonal violence (fifth). Five of the causes that were in the top ten for ages 10–24 years were also in the top ten in the 25–49-year age group: road injuries (ranked first), HIV/AIDS (second), low back pain (fourth), headache disorders (fifth), and depressive disorders (sixth). In 2019, ischaemic heart disease and stroke were the top-ranked causes of DALYs in both the 50–74-year and 75-years-and-older age groups. Since 1990, there has been a marked shift towards a greater proportion of burden due to YLDs from non-communicable diseases and injuries. In 2019, there were 11 countries where non-communicable disease and injury YLDs constituted more than half of all disease burden. Decreases in age-standardised DALY rates have accelerated over the past decade in countries at the lower end of the SDI range, while improvements have started to stagnate or even reverse in countries with higher SDI. Interpretation As disability becomes an increasingly large component of disease burden and a larger component of health expenditure, greater research and development investment is needed to identify new, more effective intervention strategies. With a rapidly ageing global population, the demands on health services to deal with disabling outcomes, which increase with age, will require policy makers to anticipate these changes. The mix of universal and more geographically specific influences on health reinforces the need for regular reporting on population health in detail and by underlying cause to help decision makers to identify success stories of disease control to emulate, as well as opportunities to improve.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/S0140-6736(20)30925-9
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn1474547X
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/5478
dc.language.isoeng
dc.publisherElsevier Ltd.spa
dc.publisher.journalThe Lancetspa
dc.relation.ispartofseriesThe Lancet, 1474-547X, Vol. 396, Nro. 10258, p. 1204 - 1222spa
dc.relation.urihttps://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30925-9/fulltext
dc.rightsAttribution 4.0 International*
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.creativecommons2020
dc.rights.localAcceso abiertospa
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subject.keywordsMortality ratespa
dc.subject.keywordsGlobal healthspa
dc.subject.keywordsLife expectancyspa
dc.titleGlobal burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019spa
dc.title.translatedGlobal burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019spa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

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