Atypical skin manifestations during immune checkpoint blockage in coronavirus disease 2019–infected patients with lung cancer

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dc.contributor.authorRolfo, Christian
dc.contributor.authorCardona-Mendoza, Andrés Felipe
dc.contributor.authorRuiz-Patiño, Alejandro
dc.contributor.authorAriza, Santiago
dc.contributor.authorZatarain-Barron, Lucia
dc.contributor.authorPino, Luis E.
dc.contributor.authorViola Muñoz, Lucía
dc.contributor.authorRusso, Alessandro
dc.contributor.authorRojas Puentes, Leonardo
dc.contributor.authorRicaurte, Luisa
dc.contributor.authorArrieta, Oscar
dc.contributor.orcidCardona-Mendoza, Andrés Felipe [0000-0002-6697-5471]
dc.contributor.orcidRojas Puentes, Leonardo [0000-0002-7865-5424]
dc.contributor.orcidViola Muñoz, Lucía [0000-0002-1647-2884]
dc.date.accessioned2020-11-04T16:18:42Z
dc.date.available2020-11-04T16:18:42Z
dc.description.abstractenglishA new coronavirus, named severe acute respiratory syndrome–coronavirus-2 by the WHO, has rapidly spread around the world since its first reported case in late December of 2019 from Wuhan, the People’s Republic of China. As of mid-April 2020, this virus has affected more than 180 countries and territories, infecting more than 1,650,000 individuals and causing over 100,000 deaths. With approximately 20 million new cases globally per year, cancer affects a substantial portion of the population. Individuals affected by cancer are more susceptible to infections owing to coexisting chronic diseases (cardiovascular, pulmonary, and diabetes), overall poor health status, and systemic immunosuppressive states caused by both cancer and the anticancer treatment. As a consequence, patients with malignancies, especially those with lung cancer who develop coronavirus disease 2019, experience more difficult outcomes. A recent multicenter study carried out by the Hubei Anti-Cancer Association has also documented that patients with lung cancer had an increased risk of death, intensive care unit requirement, risk of presenting severe or critical symptoms, and use of invasive mechanical ventilation. Here, we present two representative cases of patients with lung cancer and coronavirus disease 2019 without respiratory compromise and with atypical and severe skin manifestations—findings that could be influenced by the long-term use of anti–programmed cell death protein 1 antibody.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.jtho.2020.06.019
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn1556-0864
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlhttps://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/4619
dc.language.isospa
dc.publisherElsevierspa
dc.publisher.journalJournal of Thoracic Oncologyspa
dc.relation.ispartofseriesJournal of Thoracic Oncology, 1556-0864, Vol. 20, 2020 p. 30543-30548spa
dc.relation.urihttps://www.mdpi.com/2079-6412/10/8/728/htm
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.creativecommons2020-07-09
dc.rights.localAcceso abiertospa
dc.subject.keywordsAnti–PD-1 therapyspa
dc.subject.keywordsCOVID-19spa
dc.subject.keywordsLung cancerspa
dc.subject.keywordsErythema multiformespa
dc.subject.keywordsUrticarialspa
dc.subject.keywordsVasculitisspa
dc.titleAtypical skin manifestations during immune checkpoint blockage in coronavirus disease 2019–infected patients with lung cancerspa
dc.title.translatedAtypical skin manifestations during immune checkpoint blockage in coronavirus disease 2019–infected patients with lung cancerspa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

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