Clinical efficacy of adjunctive methods for the non-surgical treatment of peri-implantitis: a systematic review and meta-analysis

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dc.contributor.authorBarbato, Luigi
dc.contributor.authorCavalcanti, Raffaele
dc.contributor.authorRupe, Cosimo
dc.contributor.authorScartabelli, Daniele
dc.contributor.authorSerni, Lapo
dc.contributor.authorChambrone, Leandro
dc.contributor.authorCairo, Francesco
dc.date.accessioned2023-07-25T17:07:02Z
dc.date.available2023-07-25T17:07:02Z
dc.date.issued2023
dc.description.abstractenglishBackground: The aim of this systematic review (SR) was to evaluate the clinical efficacy of different adjunctive methods/therapies to the non-surgical treatment (NST) of peri-implantitis. Materials and methods: The protocol of the review was registered in PROSPERO database (CRD42022339709) and was designed according to PRISMA statement. Electronic and hand searches were performed to identify randomized clinical trials (RCTs) comparing non-surgical treatment of peri-implantitis alone versus NST plus any adjunctive method/treatment. The primary outcome was probing pocket depth (PPD) reduction. Results: Sixteen RCTs were included. Only 2 out of 1189 implants were lost and follow-up ranged from 3 to 12 months. PPD reduction across the studies varied from 0.17 to 3.1 mm, while defect resolution from 5.3% to 57.1%. Systemic antimicrobials were associated to higher PPD reduction (1.56 mm; [95% CI 0.24 to 2.89]; p = 0.02) with high heterogeneity, and treatment success (OR = 3.23; [95% CI 1.17 to 8.94]; p = 0.02), compared to NST alone. No differences were found with adjunctive local antimicrobials and lasers for PPD and bleeding on probing (BoP) reduction. Conclusions: Non-surgical treatment with or without adjunctive methods may reduce PPD and BoP even if complete resolution of the pocket is unpredictable. Among possible adjunctive methods, only systemic antibiotics seems to provide further benefits, but their usage should be considered with caution.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1186/s12903-023-03058-z
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn1472-6831
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/11158
dc.language.isoeng
dc.publisherSpringer Naturespa
dc.publisher.journalBMC Oral Healthspa
dc.relation.ispartofseriesBMC Oral Health, 1472-6831, 23 (1), 2023, 1-12spa
dc.relation.urihttps://bmcoralhealth.biomedcentral.com/articles/10.1186/s12903-023-03058-z#citeas
dc.rightsAtribución 4.0 Internacional*
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.localAcceso abiertospa
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subjectPeriimplantitisspa
dc.subjectTratamiento no quirúrgicospa
dc.subjectDesbridamiento periimplantariospa
dc.subjectMétodos complementariosspa
dc.subjectAntibióticos sistémicosspa
dc.subjectInstrumentación submarginalspa
dc.subject.keywordsPeri-implantitisspa
dc.subject.keywordsNon-surgical treatmentspa
dc.subject.keywordsPeri-implant debridementspa
dc.subject.keywordsAdjunctive methodsspa
dc.subject.keywordsSystemic antibioticsspa
dc.subject.keywordsSubmarginal instrumentationspa
dc.titleClinical efficacy of adjunctive methods for the non-surgical treatment of peri-implantitis: a systematic review and meta-analysisspa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.coarversionhttps://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

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