Prevalence of dengue antibodies in healthy children and adults in different Colombian endemic areas

Vista sencilla de ítem
dc.contributor.authorVelandia-Romero, Myriam Lucía
dc.contributor.authorCorolnel-Ruíz, Carolina
dc.contributor.authorCastro Bonilla, Lorena
dc.contributor.authorCamacho Ortega, Sigrid Johanna
dc.contributor.authorCalderón-Peláez, María Angélica
dc.contributor.authorCastellanos, Angélica
dc.contributor.authorOlano, Víctor Alberto
dc.contributor.authorPorras-Ramírez, Alexandra
dc.contributor.authorArevalo-Herrera, Myriam
dc.contributor.authorVillamil Gómez, Wilmer Ernesto
dc.contributor.authorCastellanos, Jaime
dc.contributor.orcidCastellanos, Jaime [0000-0003-1596-8383]
dc.contributor.orcidOlano, Víctor Alberto [0000-0003-4010-0973]
dc.contributor.orcidVelandia-Romero, Myriam Lucía [0000-0002-3340-7304]
dc.contributor.orcidPorras-Ramírez, Alexandra [0000-0002-0800-1388]
dc.contributor.orcidCoronel-Ruiz, Carolina [0000-0003-2202-5682]
dc.contributor.orcidCamacho Ortega, Sigrid Johanna [0000-0002-3145-4748]
dc.contributor.orcidCorolnel-Ruíz, Carolina [0000-0003-2202-5682]
dc.contributor.orcidCorolnel-Ruíz, Carolina [0000-0003-2202-5682]
dc.date.accessioned2020-02-12T18:10:55Z
dc.date.available2020-02-12T18:10:55Z
dc.date.issued2020
dc.description.abstractenglishObjectives Colombia is a dengue hyperendemic country; however, the prevalence of antibodies against dengue in the general population including the inhabitants of rural areas is unknown. This study aimed to determine the prevalence of dengue IgM and IgG antibodies in healthy children and adults in urban and rural areas of seven different endemic regions in Colombia between 2013 and 2015. Design or method Blood samples from healthy volunteers (1,318) were processed by serology (by indirect IgG and capture IgM and IgG ELISA) and molecular tests to detect viral RNA and circulating serotypes. Results The seroprevalence of IgG for dengue were 85% in children and over 90% for adults. In addition to the high IgM positive rate (14.9%) and secondary recent infection marker rate (capture IgG, 16%), 8.4% of the healthy volunteers were positive for dengue virus (DENV) RNA. Conclusion This study confirmed the broad and permanent circulation of DENV in Colombia and the high rates of infection and reinfection suffered by its inhabitants. This information can be used by the health authorities to strengthen vector control and vaccine policies and review the algorithms of diagnosis and disease management in children and adults.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.ijid.2019.10.045
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn1201-9712
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/1930
dc.language.isoeng
dc.publisherElsevierspa
dc.publisher.journalInternational Journal of Infectious Diseasesspa
dc.relation.ispartofseriesInternational Journal of Infectious Diseases, 1201-9712, Vol. 91, 2020, p. 9-16spa
dc.relation.urihttps://www.sciencedirect.com/science/article/pii/S1201971219304394
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf441
dc.rights.creativecommons2020
dc.rights.localAcceso abiertospa
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subject.decsAnticuerposspa
dc.subject.decsInfecciones por flavivirusspa
dc.subject.decsEstudios transversalesspa
dc.subject.keywordsSeroprevalencespa
dc.subject.keywordsDengue symptomaticspa
dc.subject.keywordsDengue asymptomaticspa
dc.titlePrevalence of dengue antibodies in healthy children and adults in different Colombian endemic areasspa
dc.typearticlespa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localartículospa

Archivos

Bloque original
Mostrando 1 - 1 de 1
Miniatura
Nombre:
Velandia, M., Coronel, C., Castro L., Camacho, S. , Calderon, A._2020.pdf
Tamaño:
1.29 MB
Formato:
Adobe Portable Document Format
Descripción:
Descargar
Bloque de licencias
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descripción:
Descargar

Colecciones

Artículos