Shape follows function: gastrointestinal signals for enterococcal colonization
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Fecha
2019
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Publicado en
Trends in molecular medicine, 1471-499X, Vol. 25, Nro. 6, 2019, p. 464-466
Publicado por
Elsevier
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Abstract
Vancomycin-resistant Enterococcus faecium (VRE) is a major cause of nosocomial infections. A new study by McKenney et al. (Cell Host Microbe 2019;25:695–705.e5) reports that VRE undergo a morphotype switch in response to lithocholic acid (LCA) to facilitate gastrointestinal (GI) tract colonization. This metabolic cue is a potential target to decrease VRE colonization and subsequent transmission of antibiotic resistance
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Keywords
Antibiotic resistance, Daptomycin, Enterococcus
Temáticas
Tracto gastrointestinal
Farmacorresistencia microbiana
Infección
Farmacorresistencia microbiana
Infección