Evaluation of antioxidant capacity and antifungal activity of the total ethanolic extract and fractions from teloschistes exilis (Michx.) vain.

Vista sencilla de ítem
dc.contributor.authorBeltrán Hernández, M.F
dc.contributor.authorRodríguez Romero, M.L
dc.contributor.authorMoncada Cárdenas, B.
dc.contributor.authorPombo Ospina, L.M.
dc.contributor.authorPedraza Arévalo, L.C
dc.contributor.authorAndrade Barreiro, William Alejandro
dc.contributor.authorRodríguez Aguirre, Oscar Eduardo
dc.contributor.orcidRodríguez Aguirre, Oscar Eduardo [0000-0002-5934-0451]
dc.date.accessioned2020-03-24T14:49:31Z
dc.date.available2020-03-24T14:49:31Z
dc.date.issued2019
dc.description.abstractenglishTeloschistes exilis (Michx.) Vain is an underexplored lichen. In the last decades, there has been a growing interest for the study of lichenic biodiversity, as a source of new natural products, because these produce potential secondary metabolites for pharmacological and industrial uses, highlighting their antioxidant and antifungal properties. For that reason, this study evaluated the antioxidant capacity with 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) radical (ABTS*+ assay) and the antifungal activity of the total ethanolic extract (EtOH) and different polarity fractions from Teloschistes exilis (Michx.) Vain against Penicillium digitatum and Aspergillus niger using disk diffusion technique. According to antioxidant activity, the best-obtained value was for the EtOH with 37.58 mg/L MeOH, with ascorbic acid. In terms of antifungal activity, for equivalent sensitivity, against Penicillium digitatum, for each mg of ketoconazole, 213.4 mg of Petroleum ether fraction were required, while for each mg of fluconazole, 228.3 mg of Petroleum ether fraction were required. Regarding to antifungal activity against Aspergillus niger, for each mg of ketoconazole, 465.6 mg of Petroleum ether fraction are required, while for each mg of fluconazole, 174.6 mg of Petroleum ether fraction are needed. The highest polarity solvents have a better relative antioxidant activity in relation with standard solutions, whereas susceptibility tests applied for Aspergillus niger and Penicillium digitatum showed the best antifungal activity for the low polarity fraction of Petroleum ether for both controls. Considering that are fractions, the antioxidant and antifungal potential of Teloschistes exilis (Michx.) Vain should be elucidated in posterior studies.eng
dc.format.mimetypeapplication/pdf
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn1827-8620
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/2086
dc.language.isoeng
dc.publisherSilaespa
dc.publisher.journalPharmacologyOnLinespa
dc.relation.ispartofseriesPharmacologyOnLine, 1827-8620, Vol. 3, 2019, p.28-35spa
dc.relation.urihttps://pharmacologyonline.silae.it/files/archives/2019/vol3/PhOL_2019_3_A003_Beltran.pdf
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf34
dc.rights.creativecommons2019
dc.rights.localAcceso cerradospa
dc.subject.decsLíquenesspa
dc.subject.decsFormas de los organismosspa
dc.subject.decsMecanismos moleculares de acción farmacológicaspa
dc.subject.keywordsLichenspa
dc.subject.keywordsSecondary metabolitesspa
dc.subject.keywordsTeloschistes exilisspa
dc.subject.keywordsVainspa
dc.subject.keywordsAntioxidantspa
dc.subject.keywordsAntifungalspa
dc.titleEvaluation of antioxidant capacity and antifungal activity of the total ethanolic extract and fractions from teloschistes exilis (Michx.) vain.spa
dc.title.translatedEvaluation of antioxidant capacity and antifungal activity of the total ethanolic extract and fractions from teloschistes exilis (Michx.) vain.
dc.typearticlespa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localartículospa

Archivos

Bloque original
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
Beltrán Hernández, M.F..pdf
Tamaño:
516.68 KB
Formato:
Adobe Portable Document Format
Descripción:
Descargar
Bloque de licencias
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descripción:
Descargar

Colecciones

Artículos