The rise of the Enterococcus: Beyond vancomycin resistance

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dc.contributor.authorArias, César A.
dc.contributor.authorBeral, Valerie
dc.date.accessioned2020-08-12T18:14:42Z
dc.date.available2020-08-12T18:14:42Z
dc.date.issued2012
dc.description.abstractenglishThe genus Enterococcus includes some of the most important nosocomial multidrug-resistant organisms, and these pathogens usually affect patients who are debilitated by other, concurrent illnesses and undergoing prolonged hospitalization. This Review discusses the factors involved in the changing epidemiology of enterococcal infections, with an emphasis on Enterococcus faecium as an emergent and challenging nosocomial problem. The effects of antibiotics on the gut microbiota and on colonization with vancomycin-resistant enterococci are highlighted, including how enterococci benefit from the antibiotic-mediated eradication of Gram-negative members of the gut microbiota. Analyses of enterococcal genomes indicate that there are certain genetic lineages, including an E. faecium clade of ancient origin, with the ability to succeed in the hospital environment, and the possible virulence determinants that are found in these genetic lineages are discussed. Finally, we review the most important mechanisms of resistance to the antibiotics that are used to treat vancomycin-resistant enterococci.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1038/nrmicro2761
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn1740-1534
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlhttps://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/3769
dc.language.isoeng
dc.publisherSpringer Naturespa
dc.publisher.journalNature reviews microbiologyspa
dc.relation.ispartofseriesNature reviews microbiology, 1740-1534, Vol. 10, Nro. 4, 2012, p. 266-278spa
dc.relation.urihttps://www.nature.com/articles/nrmicro2761
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.creativecommons2012-03-16
dc.rights.localAcceso abiertospa
dc.subject.keywordsAntimicrobial resistancespa
dc.subject.keywordsAntimicrobialsspa
dc.subject.keywordsBacteriaspa
dc.subject.keywordsBacterial pathogenesisspa
dc.subject.keywordsClinical microbiologyspa
dc.titleThe rise of the Enterococcus: Beyond vancomycin resistancespa
dc.title.translatedThe rise of the Enterococcus: Beyond vancomycin resistancespa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

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