Dengue-chikungunya coinfection outbreak in children from Cali, Colombia, in 2018–2019

Vista sencilla de ítem
dc.contributor.authorCastellanos, Jaime
dc.contributor.authorJaimes, Nayeli
dc.contributor.authorCorolnel-Ruíz, Carolina
dc.contributor.authorRojas, Juan Pablo
dc.contributor.authorMejía, Luis F.
dc.contributor.authorVillarreal, Víctor H.
dc.contributor.authorMaya, Luz E.
dc.contributor.authorVelandia-Romero, Myriam Lucía
dc.contributor.orcidCastellanos, Jaime [0000-0003-1596-8383]
dc.contributor.orcidVelandia-Romero, Myriam Lucía [0000-0002-3340-7304]
dc.contributor.orcidCoronel-Ruiz, Carolina [0000-0003-2202-5682]
dc.contributor.orcidCorolnel-Ruíz, Carolina [0000-0003-2202-5682]
dc.contributor.orcidCorolnel-Ruíz, Carolina [0000-0003-2202-5682]
dc.date.accessioned2020-12-04T18:41:20Z
dc.date.available2020-12-04T18:41:20Z
dc.description.abstractenglishObjective: To identify the arbovirus involved in febrile cases identified in a pediatric clinic in Cali, Valle del Cauca province, Colombia, and study the clinical characteristics. Methods: A descriptive, prospective study enrolled 345 febrile children for 12 months in a pediatric clinic. Serum samples and medical record registers documenting signs and symptoms were analyzed to detect DENV, CHIKV, and ZIKV by reverse transcription-polymerase chain reaction and serology methods. Diagnosis at the time of admission and discharge were compared based on laboratory test results. Results: All patients were diagnosed as severe dengue at admission. Molecular detection and serology tests identified 143 CHIKV-positive (41.4%), 20 DENV-positive (5.8%), and 123 DENV-CHIKV coinfection patients (35.7%). DENV or CHIKV serology test results of these double-infected patients yielded poor performance to confirm patient cases. ZIKV infection was detected in 5 patients (1.4%) as double or triple infections. Conclusion: A sustained CHIKV circulation and transmission was confirmed causing febrile illness in children and indicating that this virus spreads even during the regular DENV season, leading to double infections and altering clinical symptoms. Specific clinical tests are necessary to closely identify the arbovirus involved in causing infectious diseases that can help in better treatment and mosquito-transmitted virus surveillance.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.ijid.2020.10.022
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn1201-9712
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/5173
dc.language.isoeng
dc.publisherElsevierspa
dc.publisher.journalInternational journal of infectious diseasesspa
dc.relation.ispartofseriesInternational journal of infectious diseases, 1201-9712, Vol. 102, 2021, p. 97-102spa
dc.relation.urihttps://www.sciencedirect.com/science/article/pii/S1201971220322268?dgcid=rss_sd_all
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.creativecommons2020
dc.rights.localAcceso abiertospa
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subject.keywordsDengue feverspa
dc.subject.keywordsChikungunya feverspa
dc.subject.keywordsRT-PCRspa
dc.subject.keywordsSerologyspa
dc.subject.keywordsArbovirusspa
dc.titleDengue-chikungunya coinfection outbreak in children from Cali, Colombia, in 2018–2019spa
dc.title.translatedDengue-chikungunya coinfection outbreak in children from Cali, Colombia, in 2018–2019spa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

Archivos

Bloque original
Mostrando 1 - 1 de 1
Miniatura
Nombre:
Jaime E.Castellanos, Nayeli Jaimes_2020.pdf
Tamaño:
734.39 KB
Formato:
Adobe Portable Document Format
Descripción:
Descargar
Bloque de licencias
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descripción:
Descargar

Colecciones

Artículos