SaO2 as a predictor of exercise-induced hypoxemia in chronic obstructive pulmonary disease at moderate altitude

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dc.contributor.authorColmenares, Rafael Acero
dc.contributor.authorLombo, Carlos
dc.date.accessioned2020-04-26T21:29:10Z
dc.date.available2020-04-26T21:29:10Z
dc.date.issued2019
dc.description.abstractenglishBackground: Given the high prevalence of chronic obstructive pulmonary disease (COPD) in Bogota (2630 m above the sea), screening methods are required for COPD patients who develop exercise-induced hypoxemia (EIH). Objective: The objective was to measure the productive capacity of basal oxygen saturation for the detection of EIH during the 6-min walking test (6MWT) in patients diagnosed with COPD in a hospital in Bogotá. Design: This was a cross-sectional, retrospective study. Population: Patients diagnosed with COPD with SaO2≥88% who attended the Pneumology Section of the FSFB for a 6MWT between 2013 and 2017 were included in the study. Measurements: Age, sex, anthropometric data, SaO2, SaO2 during 6MWT, and spirometry were evaluated. Results: Ninety-two patients with EIH and 32 patients without EIH were studied. Statistically significant differences were found in SaO2, minimum SaO2 during 6MWT, and BMI (90.8% vs 93%, 80.3% vs 88.9%, and 26.7 kg/m2 vs 23.8 kg/m2, respectively). FEV1 was without statistically significant differences (74.1% vs 78.6%). The ROC curve showed a better cut-off point for detecting EIH with basal SaO2≤92% (sensitivity 76.1%, specificity 62.5%, NPV 47.6%, and PPV 85.4%) and SaO2≤94% as the best sensitivity point (sensitivity 94.6%, specificity 15.6%, NPV 76.3%, and PPV 50%). Conclusion: SaO2 is not a good screening test for EIH in COPD patients at moderate altitude.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.2147/COPD.S207467
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn1178-2005
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/2404
dc.language.isoeng
dc.publisherDove Medical Pressspa
dc.publisher.journalInternational Journal of COPDspa
dc.relation.ispartofseriesInternational Journal of COPD, 1178-2005, Vol. 2019, Nro. 14, 2019, p. 1951-1958spa
dc.relation.urihttps://www.dovepress.com/sao2-as-a-predictor-of-exercise-induced-hypoxemia-in-chronic-obstructi-peer-reviewed-article-COPD
dc.rightsAttribution-NonCommercial 4.0 International*
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf98
dc.rights.creativecommons2019
dc.rights.localAcceso abiertospa
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/*
dc.subject.decsOximetríaspa
dc.subject.decsTamizaje masivospa
dc.subject.decsEnfermedades pulmonaresspa
dc.subject.keywordsCOPDspa
dc.subject.keywordsAltitudespa
dc.subject.keywordswalk testspa
dc.titleSaO2 as a predictor of exercise-induced hypoxemia in chronic obstructive pulmonary disease at moderate altitudespa
dc.title.translatedSaO2 as a predictor of exercise-induced hypoxemia in chronic obstructive pulmonary disease at moderate altitude
dc.typearticlespa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localartículospa

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