Diarrhea and dengue control in rural primary schools in Colombia: study protocol for a randomized controlled trial

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dc.contributor.authorOvergaard, Hans
dc.contributor.authorNeal, Alexander
dc.contributor.authorMátiz, Maria Ines
dc.contributor.authorJaramillo, Juan Felipe
dc.contributor.authorOlano, Víctor Alberto
dc.contributor.authorVargas, Sandra
dc.contributor.authorSarmiento-Senior, Diana
dc.contributor.authorLenhart, Audrey
dc.contributor.authorSeidu, Razak
dc.contributor.authorStenström, Thor Axel
dc.contributor.orcidOlano, Víctor Alberto [0000-0003-4010-0973]
dc.contributor.orcidJaramillo, Juan Felipe [0000-0001-6417-8578]
dc.contributor.orcidSarmiento-Senior, Diana [0000-0002-9959-3226]
dc.date.accessioned2019-09-16T14:26:10Z
dc.date.available2019-09-16T14:26:10Z
dc.date.issued2012
dc.description.abstractenglishBackground: Diarrheal diseases and dengue fever are major global health problems. Where provision of clean water is inadequate, water storage is crucial. Fecal contamination of stored water is a common source of diarrheal illness, but stored water also provides breeding sites for dengue vector mosquitoes. Poor household water management and sanitation are therefore potential determinants of both diseases. Little is known of the role of stored water for the combined risk of diarrhea and dengue, yet a joint role would be important for developing integrated control and management efforts. Even less is known of the effect of integrating control of these diseases in school settings. The objective of this trial was to investigate whether interventions against diarrhea and dengue will significantly reduce diarrheal disease and dengue entomological risk factors in rural primary schools. Methods/design: This is a 2×2 factorial cluster randomized controlled trial. Eligible schools were rural primary schools in La Mesa and Anapoima municipalities, Cundinamarca, Colombia. Eligible pupils were school children in grades 0 to 5. Schools were randomized to one of four study arms: diarrhea interventions (DIA); dengue interventions (DEN); combined diarrhea and dengue interventions (DIADEN); and control (C). Schools were allocated publicly in each municipality (strata) at the start of the trial, obviating the need for allocation concealment. The primary outcome for diarrhea is incidence rate of diarrhea in school children and for dengue it is density of adult female Aedes aegypti per school. Approximately 800 pupils from 34 schools were enrolled in the trial with eight schools in the DIA arm, nine in the DEN, eight in the DIADEN, and nine in the control arms. The trial status as of June 2012 was: completed baseline data collections; enrollment, randomization, and allocation of schools. The trial was funded by the Research Council of Norway and the Lazos de Calandaima Foundation. Discussion: This is the first trial investigating the effect of a set of integrated interventions to control both dengue and diarrhea. This is also the first trial to study the combination of diarrhea-dengue disease control in school settings.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1186/1745-6215-13-182
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn1745-6215
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/1705
dc.language.isoeng
dc.publisherBiomed Centralspa
dc.publisher.journalTrialsspa
dc.relation.ispartofseriesTrials, 1745-6215, Vol. 11, 2012, p.1-11spa
dc.relation.urihttps://trialsjournal.biomedcentral.com/articles/10.1186/1745-6215-13-182
dc.rightsAttribution 4.0 International*
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf243
dc.rights.creativecommons2012
dc.rights.localAcceso abiertospa
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subject.decsDengue -- Prevención y controlspa
dc.subject.decsInstituciones académicasspa
dc.subject.decsMedio ruralspa
dc.subject.keywordsDenguespa
dc.subject.keywordsDiarrheaspa
dc.subject.keywordsPrimary schoolsspa
dc.titleDiarrhea and dengue control in rural primary schools in Colombia: study protocol for a randomized controlled trialspa
dc.typearticlespa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localartículospa

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Overgaard H.J., Alexander N., Mátiz M.I., Jaramillo J.F., Olano V.A., Vargas S., Sarmiento D., Lenhart A., Seidu R., Stenström T.A._2012.pdf
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