Acute lymphoblastic leukemia in a 2-year-old girl whose mother was previously diagnosed with antiphospholipid syndrome: a case report
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Fecha
2015
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Publicado en
BMC Research Notes, 1756-0500, Vol. 8,Nro.148, 2015, p.1-3
Publicado por
Biomed Central
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Abstract
Background
The role of maternal exposures and conditions in the origin of childhood cancer has been a subject of growing interest, but current evidence is inconclusive.
Case presentation
We present a case detected in a multicenter case–control study evaluating the association between parental risk factors and childhood acute lymphoblastic leukemia (ALL). The patient is a Colombian girl who was diagnosed with ALL-L1 when she was 2 years old. Her mother had been diagnosed with antiphospholipid syndrome before pregnancy and had also been treated with subcutaneous injections of heparin. Other potentially relevant maternal and patient exposures are also reported in this paper.
Conclusion
We hypothesize that the maternal autoimmune disease could be a contributor in the causality network of the daughter’s leukemia. However, the role of other exposures cannot be excluded.
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Keywords
Acute lymphoblastic leukemia, Case report, Antiphospholipid syndrome
Temáticas
Enfermedad por anticuerpos antimembrana basal glomerular
Síndrome antifosfolípido
Enfermedades del sistema inmune
Síndrome antifosfolípido
Enfermedades del sistema inmune