A new generation of vaccines in the age of immunotherapy

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dc.contributor.authorFriedlaender, Alex
dc.contributor.authorArrieta, Oscar
dc.contributor.orcidAddeo, Alfredo [https://orcid.org/0000-0003-0988-0828]
dc.contributor.orcidGiovannetti, Elisa [https://orcid.org/0000-0002-7565-7504]
dc.contributor.orcidRusso, Alessandro [https://orcid.org/0000-0002-3365-1972]
dc.contributor.orcidde Miguel-Perez, Diego [https://orcid.org/0000-0002-2822-4466]
dc.contributor.orcidCardona, Andrés Felipe [https://orcid.org/0000-0003-3525-4126]
dc.contributor.orcidRolfo, Christian [https://orcid.org/0000-0002-5109-0267]
dc.date.accessioned2022-03-05T17:55:44Z
dc.date.available2022-03-05T17:55:44Z
dc.date.issued2021
dc.description.abstractPurpose of review Cancer vaccines are one of the most extensively studied immunotherapy type in solid tumors. Despite favorable presuppositions, so far, the use of cancer vaccines has been associated with disappointing results. However, a new generation of vaccines has been developed, promising to revolutionize the immunotherapy field. Recent findings In this review, we aim to highlight the advances in cancer vaccines and the remaining hurdles to overcome. Summary Cancer vaccination has experienced tremendous progress in the last decade, with myriad promising developments. Future efforts should focus on optimization of target identification, streamlining of most appropriate vaccination strategies, and adjuvant development, as well as predictive biomarker identification. Cautious optimism is warranted in the face of early successes seen in recent clinical trials for oncolytic vaccines. If an approach were to prove successful, it could revolutionize cancer therapy the way ICIs did in the previous decade.spa
dc.description.abstractenglishPurpose of review Cancer vaccines are one of the most extensively studied immunotherapy type in solid tumors. Despite favorable presuppositions, so far, the use of cancer vaccines has been associated with disappointing results. However, a new generation of vaccines has been developed, promising to revolutionize the immunotherapy field. Recent findings In this review, we aim to highlight the advances in cancer vaccines and the remaining hurdles to overcome. Summary Cancer vaccination has experienced tremendous progress in the last decade, with myriad promising developments. Future efforts should focus on optimization of target identification, streamlining of most appropriate vaccination strategies, and adjuvant development, as well as predictive biomarker identification. Cautious optimism is warranted in the face of early successes seen in recent clinical trials for oncolytic vaccines. If an approach were to prove successful, it could revolutionize cancer therapy the way ICIs did in the previous decade.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1007/s11912-021-01130-x
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn1523-3790
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/7136
dc.language.isoeng
dc.publisherSpringerspa
dc.publisher.journalCurrent Oncology Reportsspa
dc.relation.ispartofseriesCurrent Oncology Reports, 1523-3790, Vol 23, Num 12, 2021spa
dc.relation.urihttps://link.springer.com/article/10.1007/s11912-021-01130-x
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.localAcceso abiertospa
dc.subject.keywordsImmunotherapyspa
dc.subject.keywordsLung cancerspa
dc.subject.keywordsNSCLCspa
dc.subject.keywordsVaccinesspa
dc.titleA new generation of vaccines in the age of immunotherapyspa
dc.title.translatedA new generation of vaccines in the age of immunotherapyspa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.coarversionhttps://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

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