Factores de riesgo asociados a candidemia en pacientes críticos no neutropénicos en Colombia

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dc.contributor.authorOrtíz Ruiz, G.
dc.contributor.authorOsorio, J.
dc.contributor.authorValderrama, S.
dc.contributor.authorÁlvarez, D.
dc.contributor.authorElías Díaz, R.
dc.contributor.authorCalderón, J.
dc.contributor.authorBallesteros, D.
dc.contributor.authorFranco, A.
dc.date.accessioned2020-07-30T17:06:51Z
dc.date.available2020-07-30T17:06:51Z
dc.date.issued2016
dc.description.abstractObjetivos Determinar los factores de riesgo asociados a candidemia en pacientes críticos de 7 unidades de cuidados intensivos de Colombia. Materiales y métodos Estudio de casos y controles pareado, multicéntrico, retrospectivo, en 7 unidades de cuidados intensivos de 3 hospitales universitarios. Se tomaron datos de duración de la estancia hospitalaria global (incluyendo salas generales) y en la unidad de cuidados intensivos. Resultados Se incluyeron 243 participantes (81 casos y 162 controles) entre enero de 2008 y diciembre de 2012. Se aislaron en orden de frecuencia C. albicans, C. tropicalis y C. parapsilosis . Los principales factores de riesgo identificados fueron: tiempo de estancia hospitalaria global > 25 días (OR 5,33; IC 95% 2,6-10,9), uso de meropenem (OR 3,75; IC 95% 1,86-7,5), cirugía abdominal (OR 2,9; IC 95% 1,39-6,06) y hemodiálisis (OR 3,35; IC 95% 1,5-7,7). No se encontraron diferencias en mortalidad entre los grupos de pacientes con candidemia y el grupo control (39,5 frente a 36,5%; p = 0,66). Conclusiones Se identificaron como factores de riesgo para candidemia en Colombia la larga estancia hospitalaria, la cirugía abdominal, el uso de meropenem y la hemodiálisis.spa
dc.description.abstractenglishObjectives Due to the increase in isolation of Candida spp. in critically ill patients, and the high mortality and economic costs which this infection entails, a study was made of the risk factors associated to candidemia in critically ill patients from 7 intensive care units in Colombia. Materials and methods A multicenter matched case-control study was conducted in 7 intensive care units of 3 university hospitals. Data on overall length of hospital stay (including both general wards and the intensive care unit) were recorded. Results A total of 243 subjects (81 cases and 162 controls) between January 2008 and December 2012 were included. In order of frequency, C. albicans , C. tropicalis and C. parapsilosis were isolated. The main identified risk factors were: overall length of hospital stay > 25 days (OR 5.33, 95% CI 2.6-10.9), use of meropenem (OR 3.75, 95% CI 1.86-7.5), abdominal surgery (OR 2.9, 95% CI 1.39-6.06) and hemodialysis (OR 3.35, 95% CI 1.5-7.7). No differences in mortality between patients with candidemia and controls were found (39.5 vs. 36.5%, respectively, P = .66) were found. Conclusions In Colombia, a long hospital stay, abdominal surgery, the use of meropenem and hemodialysis were identified as risk factors for candidemia.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://dx.doi.org/10.1016/j.medin.2015.08.001
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn0210-5691
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlhttps://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/3623
dc.language.isospa
dc.language.isoeng
dc.publisherElsevierspa
dc.publisher.journalMedicina Intensivaspa
dc.relation.ispartofseriesMedicina Intensiva, 0210-5691, Vol 40, Nro 3, 2016, p. 139-144spa
dc.relation.urihttps://www-clinicalkey-es.ezproxy.unbosque.edu.co/#!/content/playContent/1-s2.0-S0210569115001941?returnurl=https:%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0210569115001941%3Fshowall%3Dtrue&referrer=https:%2F%2Fresolver.ebscohost.com%2Fopenurl%3Fsid%3DEBSCO%253aedselp%26genre%3Darticle%26issn%3D02105691%26ISBN%3D%26volume%3D40%26issue%3D3%26date%3D20160401%26spage%3D139%26pages%3D139-144%26title%3DMedicina%2Bintensiva%26atitle%3DFactores%2Bde%2Briesgo%2Basociados%2Ba%2Bcandidemia%2Ben%2Bpacientes%2Bcr%25c3%25adticos%2Bno%2Bneutrop%25c3%25a9nicos%2Ben%2BColombia%26aulast%3DOrt%25c3%25adz%2BRuiz%252c%2BG.%26id%3DDOI%253a10.1016%252fj.medin.2015.08.001%26site%3Dftf-live%26SToken%3DA0ICm4c692cl8XukVJlxpxS1iZIFHm40FMYEFosFqvXWGUeG0jFKCYVSEEIHVxZEgYXok2kq9ioSnSz12gQilztSWmPTJJNJtAzNpu3nUo2L5LOsLUFcBAHGRgCFtnprHnnsZ8_hOL_f_T9La7U4Ni2VEIXHIhcAX7lAiD_YT3qNyu1siBbQ24bKiocHXeha6KbxIaNRUF971INn5H69394GsksyGQTwzG4AsPSgmveCbN_sbtubaGR7mnz0wK4SgYbmK18Ba5aaOtaj6HwUy09ujHo
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.creativecommons2016
dc.rights.localAcceso abiertospa
dc.subjectCandidaspa
dc.subjectFactores de riesgospa
dc.subjectMortalidadspa
dc.subjectCuidado intensivospa
dc.subjectCandidiasis invasivaspa
dc.subject.keywordsCandidaspa
dc.subject.keywordsRisk factorsspa
dc.subject.keywordsMortalityspa
dc.subject.keywordsIntensive carespa
dc.subject.keywordsInvasive candidiasisspa
dc.titleFactores de riesgo asociados a candidemia en pacientes críticos no neutropénicos en Colombiaspa
dc.title.translatedRisk factors for candidemia in non-neutropenic critical patients in Colombiaspa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

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