Factors associated with dengue virus infection and reinfection in asymptomatic children in two Colombian municipalities

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dc.contributor.authorCastro Bonilla, Lorena del Pilar
dc.contributor.authorCorolnel-Ruíz, Carolina
dc.contributor.authorParra-Alvarez, Shirly
dc.contributor.authorCastellanos, Jaime
dc.contributor.authorPorras-Ramírez, Alexandra
dc.contributor.authorVelandia-Romero, Myriam Lucía
dc.contributor.orcidCastellanos, Jaime [0000-0003-1596-8383]
dc.contributor.orcidVelandia-Romero, Myriam Lucía [0000-0002-3340-7304]
dc.contributor.orcidPorras-Ramírez, Alexandra [0000-0002-0800-1388]
dc.contributor.orcidCoronel-Ruiz, Carolina [0000-0003-2202-5682]
dc.contributor.orcidCastro Bonilla, Lorena del Pilar [0000-0002-0532-5344]
dc.contributor.orcidCorolnel-Ruíz, Carolina [0000-0003-2202-5682]
dc.contributor.orcidCorolnel-Ruíz, Carolina [0000-0003-2202-5682]
dc.date.accessioned2020-05-18T08:11:00Z
dc.date.available2020-05-18T08:11:00Z
dc.date.issued2018
dc.description.abstractenglishDengue is the most important arbovirosis in the world. In this study, we assessed the knowledge, attitudes, and practices (KAP) regarding dengue in parents from two small Colombian municipalities in the Cundinamarca Province. Parents and their healthy children from 4 to 14 years of age were included in some public elementary schools. After a medical examination, blood samples were taken for diagnosis of dengue using enzyme-linked immunosorbent assays (capture immunoglobulin M and capture immunoglobulin G [IgG], indirect IgG and detection non-structural viral protein 1) and detection of viral RNA by reverse transcription polymerase chain reaction. In addition, a KAP survey was applied to the children’s parents or tutors. The indirect IgG test determined that of the 347 examined children, 87.9% had a previous infection with the dengue virus (DENV), 12.7% of them were positive for viral RNA (asymptomatic infection), and 32.0% presented reinfections. Risk factors evaluation showed that children aged 8 years and older living in the municipalities for more than 7 years were more likely to be infected or reinfected by DENV. In the same way, poor nutrition, lack of water supply, sewer service, or waste disposal services could raise the likelihood of dengue infections. The surveys indicated that parents have unhealthy practices and a low knowledge about the transmission of the disease, which could result in an increase of mosquito breeding sites, allowing sustained dengue transmission.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.4269/ajtmh.17-0617
dc.identifier.issn1476-1645
dc.identifier.urihttps://hdl.handle.net/20.500.12495/2918
dc.language.isoeng
dc.publisherBaltimorespa
dc.publisher.journalAmerican Journal of Tropical Medicine and Hygienespa
dc.relation.ispartofseriesAmerican Journal of Tropical Medicine and Hygiene, 1476-1645, Vol 99, Num 6, 2018, pag 1422-1429spa
dc.relation.urihttps://www.ajtmh.org/content/journals/10.4269/ajtmh.17-0617
dc.rights.creativecommons2018
dc.rights.localAcceso cerradospa
dc.subject.decsVirus del dengue -- Epidemiologíaspa
dc.subject.decsInfecciones asintomáticasspa
dc.subject.decsAtributos de enfermedadspa
dc.titleFactors associated with dengue virus infection and reinfection in asymptomatic children in two Colombian municipalitiesspa
dc.title.translatedFactors associated with dengue virus infection and reinfection in asymptomatic children in two Colombian municipalitiesspa
dc.typearticlespa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localartículospa

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