Cancer cachexia affects patients with head and neck cancer in all stages of disease: a prospective cross-sectional study

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dc.contributor.authorSolís Martínez, Obed
dc.contributor.authorÁlvarez Altamirano, Karolina
dc.contributor.authorCardenas, Diana
dc.contributor.authorTrujillo Cabrera, Yanelly
dc.contributor.authorFuchs Tarlovsky, Vanessa
dc.date.accessioned2022-02-02T19:39:16Z
dc.date.available2022-02-02T19:39:16Z
dc.date.issued2020
dc.description.abstractenglishThe aim of the study was to determine the prevalence of cancer cachexia according to the clinical stage and determine differences in body composition, usual energy intake, and proinflammatory profile between cachectic and non-cachectic patients newly diagnosed with head and neck squamous cell carcinoma (HNSCC). A cross-sectional study was conducted in adult patients diagnosed with HNSCC admitted to the oncology unit before starting cáncer treatment. Cancer cachexia was assessed according to Fearon criteria, and patients were divided into two groups: cachectic and non-cachectic patients. Body composition measured by bioelectrical impedance, energy intake, and biochemical and inflammatory markers were assessed. Comparative analyses were performed Student’s-T test, using one-way ANOVA, chi-square and Mann Whitney-U test. Of the 79 consecutive patients included in the analysis, 72% (n¼57; 61 ± 15 years) were classified as cachectic and 28% (n¼22;59 ± 10 years) as non-cachectic. According to clinical stage, the prevalence of cachexia was stage I¼8.8%, stage II ¼ 15.8%, stage III ¼ 33.3% and stage IV ¼ 42.1% (P¼0.564) and phase angle showed to be different between these groups (P<0.05). Body composition showed that fatfree mass and total body water were significantly lower in patients with cachexia (p<0.05). No differences were observed in phase angle, food intake or inflammatory markers between cachectic and non-cachectic patients. Cancer-cachexia is prevalent in all clinical stages in newly diagnosed patients with HNSCC. Early identification of cancer cachexia will allow initiate specialized nutrition support in a timely manner.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1080/01635581.2020.1869792
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn1532-7914
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/6709
dc.language.isoeng
dc.publisherTaylor & Francis Groupspa
dc.publisher.journalNutrition and Cancerspa
dc.relation.ispartofseriesNutrition and Cancer, 1532-7914, 2020spa
dc.relation.urihttps://www.tandfonline.com/doi/full/10.1080/01635581.2020.1869792
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.localAcceso abiertospa
dc.subjectCaquexiaspa
dc.subjectMasticaciónspa
dc.subjectHigiene oralspa
dc.subjectPérdida de dientesspa
dc.subjectDenticiónspa
dc.subject.keywordsCachexiaspa
dc.subject.keywordsDentitionspa
dc.subject.keywordsMasticationspa
dc.subject.keywordsOral hygienespa
dc.subject.keywordsTooth lossspa
dc.titleCancer cachexia affects patients with head and neck cancer in all stages of disease: a prospective cross-sectional studyspa
dc.title.translatedCancer cachexia affects patients with head and neck cancer in all stages of disease: a prospective cross-sectional studyspa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

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