Biomarcadores en espondiloartropatías

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dc.contributor.authorRomero-Sánchez, Consuelo
dc.contributor.authorLondoño, John
dc.contributor.authorDe Avila, Juliette
dc.contributor.authorValle-Oñate, Rafael
dc.contributor.orcidRomero-Sánchez, Consuelo [0000-0002-6973-7639]
dc.date.accessioned2020-08-31T08:47:29Z
dc.date.available2020-08-31T08:47:29Z
dc.date.issued2010
dc.description.abstractenglishAmong rheumatic diseases and specifically spondyloarthropathies (SpA), the study of biomarkers, defined as molecules that reflect either biologic or specific pathological process, is an important and necessary area in basic and clinical research, being a consequence or the response of an intervention. Other markers provide information about the pathogenesis of this disease. Recently, HLA-B27 has been used as diagnostic criteria to detect SpA. Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and Bath Ankylosing Spondylitis Functional Index (BASFI) are clinical scores used to assess disease activity. A new activity index, Ankylosing Spondylitis Disease Activity Score (ASDAS) considers erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) as biomarkers. This review describes the state of the art of research on SpA biomarkers. There are promising new candidates as biomarkers such as metallopro-teinase 3, Type II collagen neoepitopes (C2C and C1-2C), C-propeptide of Type II collagen (CPII), aggrecan 846 epitope, macrophage colony stimulating factor, serum amyloid A protein and interleukin-6, among others.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://dx.doi.org/10.4067/S0034-98872010000900015
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn0034-9887
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlhttps://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/3878
dc.language.isospa
dc.language.isoeng
dc.publisherSociedad Médica de Santiagospa
dc.publisher.journalRevista médica de Chilespa
dc.relation.ispartofseriesRevista médica de Chile, 0034-9887, Vol. 138, Nro. 9, 2010 p. 1179-1185spa
dc.relation.urihttps://scielo.conicyt.cl/scielo.php?script=sci_abstract&pid=S0034-98872010000900015&lng=es&nrm=iso
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.creativecommons2010
dc.rights.localAcceso abiertospa
dc.subject.decsBiomarcadoresspa
dc.subject.decsArtropatíasspa
dc.subject.decsEnfermedades óseas infecciosasspa
dc.subject.keywordsBiological markersspa
dc.subject.keywordsJoint diseasesspa
dc.subject.keywordsSpondylitisspa
dc.titleBiomarcadores en espondiloartropatíasspa
dc.title.translatedBiomarkers for spondyloarthropathies. State of the artspa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

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