Use of critically important antimicrobial classes early in life may adversely impact bacterial resistance profiles during adult years: potential co-selection for plasmid-borne fluoroquinolone and macrolide resistance via extended-spectrum beta-lactam use in dairy cattle

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dc.contributor.authorTaylor, E. A.
dc.contributor.authorOssa Trujillo, C.
dc.contributor.authorVinasco, J.
dc.contributor.authorJordan, E. R.
dc.contributor.authorGarcía Buitrago, J. A.
dc.contributor.authorHagevoort, R.
dc.contributor.authorNorman, K. N.
dc.contributor.authorLawhon, S. D.
dc.contributor.authorPiñeiro, J. M.
dc.contributor.authorLevent, G.
dc.contributor.authorScott, H. M.
dc.date.accessioned2021-03-05T15:41:57Z
dc.date.available2021-03-05T15:41:57Z
dc.date.issued2020
dc.description.abstractenglishThe transfer of antimicrobial resistance genes commonly occurs via vertical and horizontal gene transfer, as such genes are often found on the same mobile genetic element. This occurrence can lead to the co‐selection of resistance to antimicrobials without their application. Dairy cattle located in the south‐western United States were enrolled in a matched‐pair longitudinal study to evaluate the effects of a two‐dose ceftiofur treatment for metritis on levels of third‐generation cephalosporin resistance among faecal Escherichia coli temporally. Escherichia coli chosen for further investigation were isolated on selective media, harboured extended‐spectrum beta‐lactam, fluoroquinolone and macrolide resistance genes. This combination has previously been unreported; importantly, it included genes encoding for resistance to antibiotics that can only be used in dairy cattle less than 20 months of age. Fluoroquinolones, macrolides and third and higher generation cephalosporins are considered critically important and highest priority for human medicine by the World Health Organization.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1111/lam.13419
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn1472-765X
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/5558
dc.language.isoeng
dc.publisherThe Society for Applied Microbiologyspa
dc.publisher.journalLetters in Applied Microbiology;spa
dc.relation.ispartofseriesLetters in Applied Microbiology, 1472-765X, 2020spa
dc.relation.urihttps://sfamjournals.onlinelibrary.wiley.com/doi/10.1111/lam.13419
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.creativecommons2020
dc.rights.localAcceso abiertospa
dc.subject.keywordsAntimicrobial resistancespa
dc.subject.keywordsDairy cowsspa
dc.subject.keywordsFluoroquinolonesspa
dc.subject.keywordsMacrolidesspa
dc.subject.keywordsThird‐generation cephalosporinsspa
dc.titleUse of critically important antimicrobial classes early in life may adversely impact bacterial resistance profiles during adult years: potential co-selection for plasmid-borne fluoroquinolone and macrolide resistance via extended-spectrum beta-lactam use in dairy cattlespa
dc.title.translatedUse of critically important antimicrobial classes early in life may adversely impact bacterial resistance profiles during adult years: potential co-selection for plasmid-borne fluoroquinolone and macrolide resistance via extended-spectrum beta-lactam use in dairy cattlespa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

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