Factors predicting persistence of early wheezing through childhood and adolescence: A systematic review of the literature

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dc.contributor.authorRodríguez-Martínez, Carlos E.
dc.contributor.authorSossa-Briceño, Mónica P.
dc.contributor.authorCastro-Rodriguez, Jose A.
dc.date.accessioned2020-05-13T22:11:18Z
dc.date.available2020-05-13T22:11:18Z
dc.date.issued2017
dc.description.abstractenglishBackground: For the early identification of persistent asthma symptoms among young children with recurrent wheezing, it would be helpful to identify all available studies that have identified at least one factor for predicting the persistence of early wheezing. The objective of the present study was to perform a systematic review of all studies that have identified factors that predict the persistence of symptoms among young patients with recurring wheezing. Methods: A systematic review of relevant studies was conducted through searching in MEDLINE, EMBASE, CINHAL, and SCOPUS databases up to June 2016. Studies that identified predictors of persistence of wheezing illness among young children with recurrent wheezing were retrieved. Two independent reviewers screened the literature and extracted relevant data. Results: The literature search returned 649 references, 619 of which were excluded due to their irrelevance. Five additional studies were identified from reference lists, and 35 studies were finally included in the review. Among all the identified predictors, the most frequently identified ones were the following: family asthma or atopy; personal history of atopic diseases; allergic sensitization early in life; and frequency, clinical pattern, or severity of wheezing/symptoms. Conclusion: Parental asthma (especially maternal), parental allergy, eczema, allergic rhinitis, persistent wheezing, wheeze without colds, exercise-induced wheeze, severe wheezing episodes, allergic sensitization (especially polysensitization), eosinophils (blood or eosinophil cationic protein in nasal sample), and fraction of exhaled nitric oxide were risk factors predicting persistence of early wheezing through school age. All of them are included in conventional algorithms, for example, Asthma Predictive Index and its modifications, for predicting future asthma.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.2147/JAA.S128319
dc.identifier.issn1178-6965
dc.identifier.urihttps://hdl.handle.net/20.500.12495/2734
dc.language.isoeng
dc.publisherDove Medical Pressspa
dc.publisher.journalJournal of asthma and allergyspa
dc.relation.ispartofseriesJournal of asthma and allergy, 1178-6965, Vol. 10, 2017, p 83-98spa
dc.relation.urihttps://www.dovepress.com/factors-predicting-persistence-of-early-wheezing-through-childhood-and-peer-reviewed-article-JAA
dc.rightsAttribution 4.0 International*
dc.rights.creativecommons2017
dc.rights.localAcceso abiertospa
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subject.decsRuidos respiratoriosspa
dc.subject.decsRevisión sistemáticaspa
dc.subject.decsEstudios longitudinalesspa
dc.subject.keywordsBirth cohortspa
dc.subject.keywordsContinuancespa
dc.subject.keywordsInfantile asthmaspa
dc.titleFactors predicting persistence of early wheezing through childhood and adolescence: A systematic review of the literaturespa
dc.typearticlespa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localartículospa

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