Teaching case: A man with a progressive gait impairment and visual compromise

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dc.contributor.authorToro, Jaime
dc.contributor.authorBurbano, Lisseth Estefania
dc.contributor.authorZamora, Adrián
dc.contributor.authorJones, Erica
dc.contributor.orcidToro, Jaime [0000-0001-7129-0058]
dc.date.accessioned2020-11-23T17:37:51Z
dc.date.available2020-11-23T17:37:51Z
dc.date.issued2015
dc.description.abstractenglishPrimary progressive multiple sclerosis can present with a wide variety of symptoms. We report a case of a 52-year-old man presenting with visual symptoms and gait impairment in whom a diagnosis of a primary progressive multiple sclerosis was established. Symptomatic treatment with dalfampridine was started but did not result in a considerable improvement. Gait disorders in multiple sclerosis are common and can have a considerable effect over the patient׳s quality of life. Dalfampridine is the first drug approved for the symptomatic treatment of gait in MS, although only a 40% of patients show an objective response to this medication. Primary progressive multiple sclerosis represents a therapeutic challenge. Currently, there are no disease modifying treatments approved but there are several medications undergoing assessment for this indication. Further research in the underlying pathophysiology of PPMS will help us develope more successful disease-modifying treatments. Meanwhile, a symptomatic approach should be offered in order to improve the patient׳s quality of life.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.msard.2015.02.001
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn2211-0356
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/5116
dc.language.isoeng
dc.publisherElsevierspa
dc.publisher.journalMultiple Sclerosis and Related Disordersspa
dc.relation.ispartofseriesMultiple Sclerosis and Related Disorders, 2211-0356, Vol. 4, No. 2, 2015, p. 176-179spa
dc.relation.urihttps://www.msard-journal.com/article/S2211-0348(15)00008-5/fulltext
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.creativecommons2015-03
dc.rights.localAcceso abiertospa
dc.subject.keywordsDalfampridinespa
dc.subject.keywordsGait disordersspa
dc.subject.keywordsPrimary progresive multiple sclerosisspa
dc.titleTeaching case: A man with a progressive gait impairment and visual compromisespa
dc.title.translatedTeaching case: A man with a progressive gait impairment and visual compromisespa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

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