Dissemination of high-risk clones of extensively drug-resistant pseudomonas aeruginosa in Colombia

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dc.contributor.authorCorrea, Adriana
dc.contributor.authordel Campo, Rosa
dc.contributor.authorPerenguez, Marcela
dc.contributor.authorBlanco, Victor M.
dc.contributor.authorRodríguez-Baños, Mercedes
dc.contributor.authorPerez, Federico
dc.contributor.authorMaya, Juan J.
dc.contributor.authorRojas, Laura
dc.contributor.authorCantón, Rafael
dc.contributor.authorArias, Cesar A.
dc.contributor.authorVillegas, María Virginia
dc.contributor.orcidVillegas, María Virginia [0000-0003-1898-9067]
dc.date.accessioned2020-08-06T19:35:16Z
dc.date.available2020-08-06T19:35:16Z
dc.date.issued2020
dc.description.abstractenglishThe ability of Pseudomonas aeruginosa to develop resistance to most antimicrobials represents an important clinical threat worldwide. We report the dissemination in several Colombian hospitals of two predominant lineages of extensively drug-resistant (XDR) carbapenemase-producing P. aeruginosa strains. These lineages belong to the high-risk clones sequence type 111 (ST111) and ST235 and harbor blaVIM-2 on a class 1 integron and blaKPC-2 on a Tn4401 transposon, respectively. Additionally, P. aeruginosa ST1492, a novel single-locus variant of ST111, was identified. Clonal dissemination and the presence of mobile genetic elements likely explain the successful spread of XDR P. aeruginosa strains in Colombia.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1128/AAC.03926-14
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn0066-4804
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlhttps://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/3720
dc.language.isoeng
dc.publisherAmerican Society for Microbiologyspa
dc.publisher.journalAntimicrobial agents and chemotherapyspa
dc.relation.ispartofseriesAntimicrobial agents and chemotherapy, 0066-4804, Vol. 59, Nro. 4, p. 2421-2425spa
dc.relation.urihttps://aac.asm.org/content/59/4/2421.long
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.creativecommons2015-04
dc.rights.localAcceso abiertospa
dc.subject.decsInfecciones por pseudomonasspa
dc.subject.decsFarmacorresistencia bacterianaspa
dc.subject.decsColombiaspa
dc.titleDissemination of high-risk clones of extensively drug-resistant pseudomonas aeruginosa in Colombiaspa
dc.title.translatedDissemination of high-risk clones of extensively drug-resistant pseudomonas aeruginosa in Colombiaspa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

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