Porphyromonas gingivalis and IgG1 and IgG2 subclass antibodies in patients with juvenile idiopathic arthritis

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dc.contributor.authorRomero-Sánchez, Consuelo
dc.contributor.authorMalagón, Clara N
dc.contributor.authorVargas, Camilo
dc.contributor.authorPorto-Torres, María Fernanda
dc.contributor.authorChila, Lorena
dc.contributor.authorRodríguez, Constanza
dc.contributor.authorCastillo Sierra, Diana Marcela
dc.contributor.authorDe Avila, Juliette
dc.contributor.authorMosquera, Ángela Catalina
dc.contributor.authorLafaurie, Gloria Ines
dc.contributor.orcidLafaurie, Gloria Ines [0000-0003-3986-0625]
dc.contributor.orcidRomero-Sánchez, Consuelo [0000-0002-6973-7639]
dc.date.accessioned2020-04-20T01:06:16Z
dc.date.available2020-04-20T01:06:16Z
dc.date.issued2017
dc.description.abstractenglishPurpose: The purpose of this study was to evaluate the periodontal status and the presence and concentration of Porphyromonas gingivalis (P. gingivalis) and immunoglobulin G (IgG) subclass against P. gingivalis in juvenile idiopathic arthritis (JIA) and its association with rheumatic clinical activity parameters. Methods: Rheumatologic conditions and periodontal status were clinically assessed in 51 patients with JIA. P. gingivalis, IgG1 and IgG2, high-sensitivity C-reactive protein, erythrocyte sedimentation rate, rheumatoid factor (RF), anti-citrullinated protein antibodies (ACPAs), and human leukocyte antigen B27 were also evaluated. Results: Periodontitis was observed in 21.5 percent of the patients, 23.5 percent of whom were positive for P. gingivalis, which was associated with enthesitis-related arthritis (P<0.035). IgG1 against P gingivalis was associated with RF autoantibodies (P=0.05), and all patients positive for ACPAs had higher anti-P gingivalis IgG1 levels. A significant correlation was found between the presence of limited joint mobility and the plaque index in polyarticular JIA (r=0.55, P=0.028). Conclusions: An association between IgG and rheumatic disease activity markers in JIA was evident. It is important to investigate the familiar periodontal status and clinical course in JIA, especially in enthesitis-related arthritis.eng
dc.format.mimetypeapplication/pdf
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn1935-5068
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/2304
dc.language.isoeng
dc.publisherAmerican academy of pediatric dentistryspa
dc.publisher.journalJournal of dentistry for childrenspa
dc.relation.ispartofseriesJournal of dentistry for children, 1935-5068, Vol. 84, Nro. 2, 2017, p. 72-79spa
dc.relation.urihttps://www.ingentaconnect.com/content/aapd/jodc/2017/00000084/00000002/art00004
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf302
dc.rights.creativecommons2017
dc.rights.localAcceso cerradospa
dc.subject.decsPorphyromonas gingivalisspa
dc.subject.decsInmunoglobulina Gspa
dc.subject.decsArtritis juvenilspa
dc.subject.keywordsAnti-citrullinated protein antibodiesspa
dc.subject.keywordsjuvenile idiopathic rheumatoid arthritisspa
dc.subject.keywordsPeriodontal diseasespa
dc.titlePorphyromonas gingivalis and IgG1 and IgG2 subclass antibodies in patients with juvenile idiopathic arthritisspa
dc.title.translatedPorphyromonas gingivalis and IgG1 and IgG2 subclass antibodies in patients with juvenile idiopathic arthritis
dc.typearticlespa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localartículospa

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Romero-Sánchez C., Malagón C., Vargas C., Torres M.F., Moreno L.C., Rodríguez C., Castillo D.M., De Avila J., Mosquera Á.C., Lafaurie G.I._2017.docx
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