Could Increase Levels of Dickkopf-1 Protein be Considered As a Potential Biomarker for Bone Resorption in Joint and Periodontal Disease in Patients with Early Rheumatoid Arthritis?

Cargando...
Miniatura

Fecha

2016

Título de la revista

Publicado en

Arthritis & Rheumatology, meeting abstracts, 2326-5205, Session Rheumatoid Arthritis – Clinical Aspects - Poster I: Clinical Characteristics/Presentation/Prognosis, 2016, 1886-87

Publicado por

John Wiley & Sons
American College of Rheumatology

ISSN de la revista

Título del volumen

Resumen

Descripción

Abstract

Periodontitis and rheumatoid arthritis (RA) are chronic destructive inflammatory diseases with significant worldwide prevalence. They are characterized by inflammatory lesions adjacent to bone destruction involving connective tissue and bone. Dickkopf-1 (DKK-1) is a major regulator of bone mass; however, their involvement in local bone resorption is largely unknown. The aim of this study was to assess the utility of DKK-1 levels in gingival crevicular fluid (GCF) and serum as a potential predictor of bone loss in periodontal disease and/or early RA.

Palabras clave

Keywords

Temáticas

Citación

Colecciones