Targeting cell membrane adaptation as a novel antimicrobial strategy

Vista sencilla de ítem
dc.contributor.authorTran, Truc T.
dc.contributor.authorMiller, William R.
dc.contributor.authorShamoo, Yousif
dc.contributor.authorArias, César A.
dc.date.accessioned2020-07-16T20:31:54Z
dc.date.available2020-07-16T20:31:54Z
dc.date.issued2016
dc.description.abstractenglishEmergence of antibiotic resistance is an example of the incredible plasticity of bacteria to survive in all environments. The search for new antibiotics active against traditional targets is more challenging due not only to the lack of novel natural products to fulfill the current clinical needs against multidrug-resistant (MDR) bacteria, but also for the possible ‘collateral’ effects on the human microbiota. Thus, non-traditional approaches to combat MDR bacteria have been proposed. Here, we discuss the possibility of targeting the membrane response to the antibiotic attack (cell membrane adaptation) as a viable strategy to increase the activity of current antimicrobials, enhance the activity of the innate immune system and prevent development of resistance during therapy using the three-component regulatory system LiaFSR of enterococci as a model.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.mib.2016.07.002
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn1879-0364
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlhttps://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/3542
dc.language.isoeng
dc.publisherElsevierspa
dc.publisher.journalCurrent opinion in microbiologyspa
dc.relation.ispartofseriesCurrent opinion in microbiology, 1879-0364, Vol. 33, 2016, p. 91-96spa
dc.relation.urihttps://www.sciencedirect.com/science/article/abs/pii/S136952741630090X?via%3Dihub
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.creativecommons2016-07-25
dc.rights.localAcceso abiertospa
dc.subject.decsBacitracinaspa
dc.subject.decsCatelicidinasspa
dc.subject.decsEnterococcus faeciumspa
dc.titleTargeting cell membrane adaptation as a novel antimicrobial strategyspa
dc.title.translatedTargeting cell membrane adaptation as a novel antimicrobial strategyspa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

Archivos

Bloque original
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
Tran, TT, Miller, WR_2016.pdf
Tamaño:
395.03 KB
Formato:
Adobe Portable Document Format
Descripción:
Descargar
Bloque de licencias
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descripción:
Descargar

Colecciones

Artículos