A prospective cohort study to assess seroprevalence, incidence, knowledge, attitudes and practices, willingness to pay for vaccine and related risk factors in dengue in a high incidence setting

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dc.contributor.authorCastellanos, Jaime
dc.contributor.authorMartínez-Vega, Ruth Aralí
dc.contributor.authorRodriguez-Morales, Alfonso J.
dc.contributor.authorBracho-Churio, Yalil Tomás
dc.contributor.authorCastro-Salas, Mirley Enith
dc.contributor.authorGalvis-Ovallos, Fredy
dc.contributor.authorDíaz-Quijano, Ronald Giovanny
dc.contributor.authorLuna-González, María Lucrecia
dc.contributor.authorRamos-Castañeda, José
dc.contributor.authorDiaz-Quijano, Fredi Alexande
dc.contributor.orcidCastellanos, Jaime [0000-0003-1596-8383]
dc.date.accessioned2019-07-26T12:47:31Z
dc.date.available2019-07-26T12:47:31Z
dc.date.issued2016
dc.description.abstractenglishBackground: Dengue is one of the most important vector-borne diseases in the world, causing significant morbidity and economic impact. In Colombia, dengue is a major public health problem. Departments of La Guajira, Cesar and Magdalena are dengue endemic areas. The objective of this research is to determine the seroprevalence and the incidence of dengue virus infection in the participating municipalities from these Departments, and also establish the association between individual and housing factors and vector indices with seroprevalence and incidence. We will also assess knowledge, attitudes and practices, and willingness-to-pay for dengue vaccine. Methods: A cohort study will be assembled with a clustered multistage sampling in 11 endemic municipalities. Approximately 1000 homes will be visited to enroll people older than one year who living in these areas, who will be followed for 1 year. Dengue virus infections will be evaluated using IgG indirect ELISA and IgM and IgG capture ELISA. Additionally, vector indices will be measured, and adult mosquitoes will be captured with aspirators. Ovitraps will be used for continuous estimation of vector density. Discussion: This research will generate necessary knowledge to design and implement strategies with a multidimensional approach that reduce dengue morbidity and mortality in La Guajira and other departments from Colombian Caribbean.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1186/s12879-016-2055-4
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn1471-2334
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/1567
dc.language.isoeng
dc.publisherBiomed Centralspa
dc.publisher.journalBMC Infectious Diseasesspa
dc.relation.ispartofseriesBMC Infectious Diseases, 1471-2334, Vol.16, Num.705, 2016 p. 1-9spa
dc.relation.urihttps://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-016-2055-4
dc.rightsAttribution 4.0 International*
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf72
dc.rights.creativecommons2016
dc.rights.localAcceso abiertospa
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subjectDenguespa
dc.subjectSeroprevalenciaspa
dc.subjectIncidenciaspa
dc.subject.decsSalud públicaspa
dc.subject.decsEstudios seroepidemiológicosspa
dc.subject.decsVirus del denguespa
dc.subject.decsVacunas contra el denguespa
dc.subject.keywordsKnowledgespa
dc.subject.keywordsVaccinesspa
dc.subject.keywordsRisk factorsspa
dc.titleA prospective cohort study to assess seroprevalence, incidence, knowledge, attitudes and practices, willingness to pay for vaccine and related risk factors in dengue in a high incidence settingspa
dc.typearticlespa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localartículospa

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