Utilidad del diagnóstico visual (TFI) y por cuantificación de luz fluorescente (QLF) frente a microscopía de luz polarizada (PLM) y microrradiografía (TMR) en fluorosis leve y moderada en dientes primarios

Vista sencilla de ítem
dc.contributor.advisorMartínez-Mier, Ángeles
dc.contributor.advisorMartignon Biermann, Stefania
dc.contributor.authorRincón Bermúdez, Claudia Milena
dc.date.accessioned2023-03-06T12:24:30Z
dc.date.available2023-03-06T12:24:30Z
dc.date.issued2016
dc.description.abstractLa fluorosis dental es un defecto del desarrollo del esmalte relacionado con la ingesta crónica de altos niveles de fluoruro durante la formación dental. El diagnóstico se basa en hallazgos visuales, que en dentición primaria son menos evidentes que en permanentes; se realiza por medio de índices como el TFI (Thylstrup y Fejerskov), que ha sido correlacionado histológicamente con microscopía de luz polarizada (PLM). Actualmente, existen técnicas que pueden medir la fluorosis cuantitativamente, como la cuantificación por luz fluorescente (QLF) y la microrradiografía (TMR), que evalúan pérdida mineral. Hasta el momento no se conocen estudios con QLF en fluorosis de dientes primarios. Determinar la utilidad del diagnóstico visual TFI y por QLF frente a PLM y TMR, en fluorosis leve y moderada en dientes primarios. Se clasificaron dientes primarios extraídos sanos y con fluorosis dental (n=112) con el índice TFI en imágenes de estereomicroscopía; se valoró fluorosis dental con QLF en umbrales 5-15-30 por medio de análisis de la superficie y región de interés (ROI) sobre imágenes de fluorescencia y se obtuvo el valor de área (A), pérdida de fluorescencia (∆F) y ∆Q; se obtuvieron secciones (80-120µm) de ROI y, se determinó pérdida mineral (∆Z), profundidad de la lesión (LD) y capa subsuperficial (SS) con TMR. En PLM se categorizaron en sano, fluorosis leve (TFI 1-2) y moderada (TFI 3-4). Se evaluó concordancia entre TFI y PLM, correlación entre TMR y QLF con coeficiente de correlación de Spearman, correlación de PLM y TFI con QLF con Kendall Tau, análisis ROC de QLF frente a diagnóstico visual e histológico; se describieron las características de dientes primarios TFI 0-4 con cada prueba. Se presentó concordancia moderada entre TFI y PLM (kappa=0.46), correlaciones: -nula entre QLF y TMR, -moderada entre QLF-TFI (tau A=0.5, ΔF=0.58, ΔQ=0.62; p≥0.001) y -débil entre QLF y PLM (tau A=0.32, ΔF=0.37 ΔQ=0.34; p≥0.001). Se obtuvo una sensibilidad de 73.9% y especificidad de 72.5% para ΔQ frente a PLM y 75% de sensibilidad y 78% de especificidad para ΔQ frente a TFI visual para fluorosis leve.spa
dc.description.abstractenglishDental fluorosis is a developmental defect of the enamel associated to high levels of fluoride intake during dental formation. The diagnosis of fluorosis is based on visual findings that in primary teeth are milder than in permanent teeth. The TFI index (Thylstrup y Fejerskov) is used on its diagnosis, and has been correlated histologically with polarized light microscopy (PLM). Currently, there are techniques that allow for an objective measurement of fluorosis, such as QLF (Quantitative Light Fluorescence) and TMR (Transverse microradiography). Both techniques assess percentage of mineral loss. There have been no published studies reporting on the correlation among QLF and a gold standard (PLM or TMR) on fluorosis in primary teeth. To determine the validity of visual diagnosis and Quantitative Light-induced Fluorescence (QLF) versus polarized light microscopy (PLM) and microradiography (TMR) of mild and moderate fluorosis in primary teeth. Methods extracted sound and fluorotic mild and moderated primary teeth (n=112) were examined using TFI via stereomicroscopy. Fluorosis was assessed with QLF by surface analysis and region of interest (ROI) on fluorescence images; A, ∆F and ∆Q values were obtained. Teeth were cut into 80-120µm sections that included the ROI to assess with TMR (∆Z, LD and SS were collected) and PLM; sections were classified as sound, mild or moderated fluorosis. Statistical analysis: it was established concordance between TFI and PLM, Spearman's rank correlation coefficient was obtained for TMR and QLF, Kendall tau was obtained for correlation between QLF vs TFI and PLM; results of the operating characteristics analysis (ROC) of QLF were compared to visual and histological diagnosis. A description of the fluorotic primary teeth categories was done. Agreement between TFI-PLM was 83.2% (kappa=0.46), a correlation between QLF and TMR was not found. A moderate correlation between QLF and TFI (tau A=0.5, ΔF=0.58, ΔQ=0.62; p≥0.001) and a weak correlation with PLM (tau A=0.32, ΔF= 0.37 ΔQ=0.34; p≥0.001) were found. A 73.9% sensitivity and 72.5% specificity were obtained for ΔQ versus PLM and a 75% sensitivity and 78% specificity for ΔQ versus TFI for mild fluorosis diagnosis.eng
dc.description.degreelevelMaestríaspa
dc.description.degreenameMagíster en Ciencias Odontológicasspa
dc.format.mimetypeapplication/pdf
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/10114
dc.language.isospa
dc.publisher.facultyFacultad de Odontologíaspa
dc.publisher.grantorUniversidad El Bosquespa
dc.publisher.programMaestría en Ciencias Odontológicasspa
dc.relation.referencesAl-Khateeb, S., De Josselin de Jong, E., & Angmar-Månsson, B. (1997). Laser fluorescence quantification of remineralization in situ of incipient enamel lesions: influence of fluoride supplements. Caries Res, 31(2), 132–140.spa
dc.relation.referencesAngmar-Månsson, B., Ericsson, Y., & Ekberg, O. (1976). Plasma fluoride and enamel fluorosis. Calcif Tissue Res, 22(1), 77-84.spa
dc.relation.referencesAoba, T., & Fejerskov, O. (2002). Dental fluorosis: Chemistry and Biology. Crit Rev Oral Biol Med, 13(2), 155-170.spa
dc.relation.referencesBarbour, M. E., & Rees, J. S. (2004). The laboratory assessment of enamel erosion: a review. J. Dent, 32(8), 591–602.spa
dc.relation.referencesBrowne, D., Whelton, H., & O´Mullane, D. (2005). Fluoride metabolism and fluorosis. Journal of Dentistry, 33(3), 177-186.spa
dc.relation.referencesCarbajal, H., Vicente, J., & Voltz, M. (1996). La microrradiografía de contacto aplicada al estudio de la micro morfología de suelos. Anal. Edafol. Agrobiol, 25, 491-503.spa
dc.relation.referencesCarlton, R. (2011). Pharmaceutical Microscopy Polarized Light Microscopy. New York: Springer Science Business Media.spa
dc.relation.referencesCarvalho, C. et al. (2013). Dental fluorosis in the primary dentition and intake of manufactured soy-based foods with fluoride. Clinical Nutrition, 32(3), 432-437.spa
dc.relation.referencesCentral Disease Control. (7 de enero de 2011). HHS and EPA announce new scientific assessments and actions on fluoride. Obtenido de hhs web site: www.hhs.govspa
dc.relation.referencesClark, D. (1994). Trend in prevalence of dental fluorosis in North America. Community Dent. Oral Epidemiol, 22, 148-152.spa
dc.relation.referencesCochrane, N. J., Walker, G. D., & Manton, D. J. (2012). Comparison of quantitative light-induced fluorescence, digital photography and transverse microradiography for quantification of enamel remineralization. Australian Dental Journal, 57(3), 271-276. doi:DOI: 10.1111/j.1834-7819.2012.01706.xspa
dc.relation.referencesDe Josselin de Jong, E., Sundström, F., Westerling, H., Tranæus, S., Angmar-Månsson, B., & Ten Bosh, J. J. (1995). A new method for in vivo quantification of changes in initial enamel caries with laser fluorescence. Caries Res., 29(1), 2–7.spa
dc.relation.referencesDean, H. (1942). Fluorine and dental health. In F. R. Moulton (Ed.), Fluorine and dental health (pp. 23-31). Washington, D.C: American Association for the Advancement of Science.spa
dc.relation.referencesDean, H. (1993). Classification of mottled enamel diagnosis. Journal of the American Dental Association, 21, 1421-1426.spa
dc.relation.referencesDean, H. T., Arnold, F. A., Jay, P., & Knutson, J. W. (1950). Studies on mass control of dental caries through fluoridation of the public water supply. Public Health Report, 65(43), 14031408.spa
dc.relation.referencesDecreto 2024. (1984). República de Colombia: Ministerio de salud. Bogotá, Colombia. Decreto N° 3039. (10 de Agosto de 2007). Plan Nacional de Salud Pública 2007-2010, República de Colombia.spa
dc.relation.referencesDorozhkin, S. (2007). Calcium orthophosphates. J Mater Sci, 42, 1061–1095. doi:0.1007/s10853-006-1467-8spa
dc.relation.referencesDrees, L., & wilding, L. (1983). Microradiography as a submicroscopic tool. Geoderma, 30(Issues 1–4), 65-76.spa
dc.relation.referencesEanes, E. D. (1979). Enamel apatite: Chemistry, structure and properties. J Dent Res, 58(2), 829-836.spa
dc.relation.referencesEastoe, J. E., & Fejerskov, O. (1984). Composition of mature enamel protein from fluorosed teeth. In Tooth enamel (p. 326). Amsterdam, Elsevier: Fearnhead R, Suga S.spa
dc.relation.referencesEckert, M. B., Eckert, G. J., González-Cabezas, C., Cordeiro, R. C., & Ferreira-Zandona, A. G. (2016). Caries Detection around Restorations Using ICDAS and Optical Devices. J Esthet Restor Dent, 10. doi:10.1111/jerd.12183spa
dc.relation.referencesEkstrand, J., Spak, C. J., & Ehrnebo, M. (1982). Renal clearance of fluoride in a steady state condition in man: influence of urinary flow and pH changes by diet. Acta Pharmacol Toxicol (Copenh), 50(5), 321-325.spa
dc.relation.referencesElliott, J. C. (1994). Structure and Chemistry of the Apatites and Other Calcium Orthophosphates, (1st ed.). Amsterdam: Elsevier Science.spa
dc.relation.referencesEllwood, R. P., & O’Mullane, D. (1995). Enamel opacities and dental esthetics. J Public Health Dent, 55(3), 171–176.spa
dc.relation.referencesEllwood, R., Fejerskov, O., Cury, J. A., & Clarkson, B. (2008). Fluorides in caries control. En: Fejerskov O, Kidd E. Dental Caries. The Disease and its Clinical Management. Copenhagen, Denmark: Blackwell Munksgaard.spa
dc.relation.referencesEvans, R. W., & Stamm, J. W. (1991). Dental Fluorosis Following Downward Adjustment of Fluoride in Drinking Water. Journal of Public Health Dentistry, 51(2), 91–98.spa
dc.relation.referencesEverett, E. T., McHenry, M. A., Reynolds, N., Eggertsson, H., Sullivan, J., Kantmann, C., . . .Stookey, G. K. (2002). Dental fluorosis: variability among different inbred mouse strains. J Dent Res, 81(11), 794-798.spa
dc.relation.referencesFeatherstone, J. D. (1945). Clinical aspects of de/remineralization of teeth. Adv Dent Res, 49(3), 175-340.spa
dc.relation.referencesFejerskov, O. T. (1977). Clinical and structural features and possible pathogenic mechanisms of dental fluorosis. Scand J Dent Res, 85(7), 510-34.spa
dc.relation.referencesFejerskov, O., Baelum, V., & Manji, F. M. (1988). Dental fluorosis: a handbook for health workers. Copenhagen: Munksgaard.spa
dc.relation.referencesFejerskov, O., Johnson , N., & Silverstone, L. (1974). The ultrastructure of fluorosed human dental enamel. European Journal of Oral Sciences, 82(5), 357–372.spa
dc.relation.referencesFejerskov, O., Silverstone, L. M., Melsen, B., & Møller, I. J. (1975). Histological Features of Fluorosed Human Dental Enamel. Caries Res., 9(3), 190-210.spa
dc.relation.referencesFejerskov, O., Thylstrup , A., & Larsen, M. J. (1981). Rational use of fluorides in caries prevention. Acta Odontol Scand, 39, 241-249.spa
dc.relation.referencesFejerskov, O., Yaeger, J. A., & Thylstrup, A. (1979). Microradiography of the effect of acute and chronic administration of fluoride on human and rat dentine and enamel. Archs Oral Biol., 24(2), 123-130.spa
dc.relation.referencesFejerskov, O., Yanagisawa, T., Tohda, H., Larsen, M. J., Josephsen, K. J., & Mosha, H. (1991). Posteruptive changes in human dental fluorosis a histological and structural study. Proc Finn Dent Soc, 87(4), 607-619.spa
dc.relation.referencesFranco, A., Martignon, S., Saldarriaga, A., González, M., Arbeláez, M., Ocampo, A., . . . Villa, A. (2005). Total fluoride intake in children aged 22–35 months in four Colombian cities. Community Dent Oral Epidemiol, 33(1), 1–8.spa
dc.relation.referencesGonzález-Cabezas, C., Fontana, M., Gomes-Moosbauer, D., & Stookey, G. K. (2003). Early detection of secondary caries using quantitative, light-induced fluorescence. Oper Dent, 28(4), 415-422.spa
dc.relation.referencesHafström-Björkman, U., Sundström, F., & Angmar-Mansson, B. (1991). Initial caries diagnosis in rat molars using laser fluorescence. Acta Odont Scand, 49, 27-33.spa
dc.relation.referencesHamilton, I. R. (1990). Biochemical effects of fluoride on oral bacteria. J Dent Res, 69(Spec Iss), 660-667.spa
dc.relation.referencesHiller, C. R., Robinson, C., & Weatherell, J. A. (1975). Variations in the composition of developing rat incisor enamel. Calciied Tiss Res, 18(1), 1-12.spa
dc.relation.referencesHorowitz, H. S., Driscoll, W. S., Meyers, R. J., Heifetz, S. B., & Kigman, A. A. (1984). New Method of Assessing the Pre- valence of Fluorosis - The Tooth Surface Index of Fluorosis. J Am Dent Assoc., 109(1), 37-41.spa
dc.relation.referencesInstituto Nacional de Salud. (2015). Vigilancia y análisis del riesgo en salud pública, protocolo de vigilancia en salud pública exposición a flúor (centinela). Versión 2.spa
dc.relation.referencesJenkins, G., & Speirs, R. (1953). Distribution of fluorine in human enamel. J Physiol, 121, 21-28.spa
dc.relation.referencesKo, Hae-Youn, Si-Mook Kang, Hee Eun Kim, Ho-Keun Kwon, & Baek-Il Kim. (2015). Validation of quantitative light-induced fluorescence-digital (QLF-D) for the detection of approximal caries in vitro. J Dent, 43(15), 568–575.spa
dc.relation.referencesKühnisch, J., Ifland, S., Tranæus, S., Angmar-Månsson, B., Hickel, R., Stösser, L., & Heinrich Weltzien, R. (2006). Establishing quantitative light-induced fluorescence cut-offs for the detection of occlusal dentine lesions. Eur J Oral Sci, 114(6), 483–488.spa
dc.relation.referencesLevy, S. M., Warren, J. J., Broffitt, B., & Kanellis, J. M. (2006). Associations Between Dental Fluorosis of the Permanent and Primary Dentitions. Journal of Public Health Dentistry, 9, 180-184.spa
dc.relation.referencesLinden, L. A., Bjõrkman, S., & Hattab, F. (1986). The diffusion in vitro of fluoride and chlorhexidine in the enamel of human deciduous and permanent teeth. Arch Oral Biol, 31(1), 33–37.spa
dc.relation.referencesLópez Camacho, V., & Molina Saldarriaga, H. (1997). Prevalencia de fluorosis y caries dental en la zona urbana del Municipio de Yondó. Rev Fac Odontol Univ Antioq, 8(2), 34-43.spa
dc.relation.referencesMann, J., Mahmoud, W., Ernest, M., Sgan-Cohen, H., Shoshan, H., & Gedalia, I. (1990). Fluorosis and dental caries in 6-8 year-old children in a 5ppm fluoride área. Community Dentistry and Oral Epidemiology, 75, 1015-1018.spa
dc.relation.referencesMarín, L. M., Castellanos, J. E., Tenuta, L. M., Martignon, S., & Cury, J. A. (2014). Composition, mechanical properties and demineralization of fluorosed teeth. J Dent Res, 93(Spec Iss B), 869. Retrieved from (www.iadr.org).spa
dc.relation.referencesMarín, L. M., Castellanos, J. E., Tenuta, L. M., Martignon, S., & Cury, J. A. (2016). Composition, mechanical properties and demineralization of fluorosed teeth. Caries Res(in press).spa
dc.relation.referencesMartignon, S., & Granados, O. L. (2002). Prevalencia de Fluorosis Dental y Análisis de Asociación a Factores de Riesgo en Escolares de Bogotá. Rev Cient, 8(1), 19-27.spa
dc.relation.referencesMartignon, S., Marin, L. M., Castiblanco, G. A., Martinez-Mier, E. A., & Usuga-Vacca, A. (2014). Differential Diagnosis between Caries and Fluorosis: Reproducibility among Examiners on Visual Diagnosis and Histologic Confirmation.spa
dc.relation.referencesMartignon, S., Marín, L., Silva, B., Ruiz, J., González, M., Castiblanco, G., & Gamboa, L. (2015). Prevalence of fluorosis and caries in children from 4-Huila municipalities with different water fluoride levels. External funding: Colciencias-grant.spa
dc.relation.referencesMartignon, S., Marín, L., Silva, B., Ruiz, J., González, M., Castiblanco, G., & Gamboa, L. (2015). Prevalence of fluorosis and caries in children from 4-Huila municipalities with different water fluoride levels. External funding: Colciencias-grant, 442.spa
dc.relation.referencesMartinez Mier, E. A., Maupomé, G., Soto, A. E., IUreña, J. L., Katz, B. P., & Stookey, G. K. (2004). Development of a questionnaire to measure perceptions of, and concerns derived from, dental fluorosis. Community Dent Health, 21(4), 299-305.spa
dc.relation.referencesMartínez, L. M., Marulanda, E., Noreña, M., Bernal, T., & Agudelo, A. (2011). Prevalencia de fluorosis y experiencia de caries dental en un grupo de escolares en el área urbana del municipio de Yondó (Antioquia, Colombia). Rev CES Odont, 24(1), 9-16.spa
dc.relation.referencesMartínez-Mier, A. (2012). Fluoride: its Metabolism, toxicity, and role in dental health. J of evidence-based Complementary and Alternative medicine, 17(1), 28-32.spa
dc.relation.referencesMassler, M., & Schour, I. (1946). Growth of the child and the calcification pattern of the teeth. Am J Orthod Oral Surg, 32(9), 495-517.spa
dc.relation.referencesMcGrady, M., Ellwood, P. R., Taylor, A., Maguire, A., Goodwin, M., Boothman, N., & Pretty, A. I. (2012). Evaluating the use of fluorescent imaging for the quantification of dental fluorosis. doi:10.1186/1472-6831-12-47spa
dc.relation.referencesMeyer-Lueckel, H., Paris, S., & Ekstrand, K. R. (2013). Caries Management – Science and Clinical Practice (1 ed.). Stuttgart, New York: Thieme Georg Verlag.spa
dc.relation.referencesMinisterio de Salud - República de Colombia y Centro Nacional de Consultoría - CNC. (2015). Estudio Nacional de Salud Bucal IV. En: IV Estudio Nacional de Salud Bucal – ENSAB IV. Tomo I. Bogotá, Colombia: Lito Servicios ALER.spa
dc.relation.referencesMinisterio de Salud - República de Colombia, & Centro Nacional de Consultoría – CNC. (1999). Estudio Nacional de Salud Bucal. En: III Estudio Nacional de Salud Bucal - ENSAB III. Tomo VII. Bogotá, Colombia: Lito Servicios ALER.spa
dc.relation.referencesMoradian-Oldak, J. (1993). Protein- mediated enamel mineralization. Front Biosci, 17, 19962023.spa
dc.relation.referencesNeedham, G. H. (1958). The practical use of the Microscope. Springfield: Charles C Thomas.spa
dc.relation.referencesPetersen, P. (2003). The World Oral Health Report 2003: continuous improvement of oral health in the 21st century. Community Dent Oral EpidemioL, 31, 3-24.spa
dc.relation.referencesPettersson, L., Odelius, H., Lodding, A., Larsson, S., & Frostell, G. (1976). Ion probe study of fluorine gradients in outermost layers of human enamel. J Dent Res, 55(6), 980-990.spa
dc.relation.referencesPretty et al. (2012). Quantitative light fluorescence (QLF) and polarized white ligth (PWL) assessment of dental fluorosis in an epidemiological setting. doi:10.1186/1471-2458-12366spa
dc.relation.referencesPretty, I. A., Tavener, J. A., Browne, D., Bettle, D. S., Whelton, H., & Ellwood, R. P. (2006). Quantification of dental fluorosis using fluorescence imaging. Caries res, 40(5), 426-434.spa
dc.relation.referencesRadlanski, R. J., & Renz, H. (2006). Developmental movements of the inner enamel epithelium as derived from micromorphological features. Eur J Oral Sci, 114(Suppl 1), 343-348.spa
dc.relation.referencesRamírez, B. S., Franco, A. M., & Ochoa, E. M. (2009). Fluorosis dental en escolares de Instituciones Educativas Públicas de Medellín, Colombia 2006. Rev Salud Pública, 11(4), 631-640.spa
dc.relation.referencesRichards, A., Fejerskov, O., & Baelum, V. (1989). Fluoride in relation to severity of human dental fluorosis. AdvDentRes, 3(2), 147-153.spa
dc.relation.referencesRobinson, C., Brookes, S. J., Shore, R. C., & Kirkham, J. (1998). The developing enamel matrix: nature and function. Eur J Oral Sci,, 106(Supp1), 282-291.spa
dc.relation.referencesRobinson, C., Hiller, C., & Weatherell, J. (1974). Uptake of 32P- labelled phosphate into developing rat incisor enamel. Tissue Res, 15(2), 143- 152.spa
dc.relation.referencesRobinson, C., Kirkham, J., & Hallsworth, A. S. (1988). Volume distribution and concentration of protein mineral and water in developing dental enamel. Arch. Oral Bioi, 33(3), 159-162.spa
dc.relation.referencesRobinson, D., Kirkham, J., Brookes, S. J., BonassW, W. A., & Shore, R. C. (1995). The chemistry of enamel development. Int. J. Dev. Biol, 39(1), 45-152.spa
dc.relation.referencesRussell, A. L. (1963). The differential diagnosis of fluoride and non-fluoride opacities. Public Healt Detit, 21, 143-146.spa
dc.relation.referencesSabel, N. (2012). Enamel of Primary Teeth - morphological and chemical aspects. Swedish Dental Journal Supplement, 978-991.spa
dc.relation.referencesSánchez, H., Parra, J. H., & Cardona, D. (2005). Fluorosis dental en escolares del departamento de Caldas, Colombia. Biomédica, 25(1), 46-54.spa
dc.relation.referencesSkobe, Z. (2006). SEM evidence that one ameloblast secretes one keyhole-shaped enamel rod in monkey teeth. Eur J Oral Sci, 114(Suppl 1), 338-342; 349- 350, 382.spa
dc.relation.referencesSmith, C. (1998). Cellular and chemical events during enamel maturation. Crit Rev Oral Biol Med, 9(2), 128–161. doi:10.1177/10454411980090020101spa
dc.relation.referencesSmith, M. C., & Smith, I. V. (1935). The occurrence of mottled enamel on the temporary teeth. J Am. Dent. Assoc., 22, 814-817.spa
dc.relation.referencesSuma, Suma, R., Shashibhushan, K. K., Shashikiran, N. D., & Subba, R. V. (2008). Progression of artificial caries in fluorotic and nonfluorotic enamel: an in vitro study. J Clin Pediatr Dent, 33(2), 127-130.spa
dc.relation.referencesTen Cate et al. (2000). In vitro validation studies of quantitative light-induced fluorescence. Early Detection of Dental Caries II. Proceedings of the 4th Annual Indiana Conference Stookey GK (ed.) (págs. 231-250). Indianapolis, Indiana: Indiana University School of Dentistry.spa
dc.relation.referencesTen Cate, A. R. (1994). Oral histology: development, structure, and function (4th ed.). St. Louis, Missouri: Mosby.spa
dc.relation.referencesTen Cate, J. M. (1982). Duijsters PPE. Alternating demineralization and remineralization of artificial enamel lesions. Caries Res, 16(3), 201-10.spa
dc.relation.referencesTen Cate, J. M. (1999). Current concept son the theories of the mechanism of action of fluoride. Acta Odontol Scand, 57(6), 325-329.spa
dc.relation.referencesThylstrup, A. (1978). Distribution of dental fluorosis in the primary dentition. Community Dent. Oral Epidemiol. Oral Epidemiol, 6(6), 329-337.spa
dc.relation.referencesThylstrup, A., & Fejerskov, O. (1978). Clinical appearance of dental fluorosis in permanent teeth in relation to histologic changes. Community Dent. Oral Epidemiol, 6(6), 315-328.spa
dc.relation.referencesThylstrup, A., Fejerskov, O., & Mosha, H. J. (1978). A polarized light and microradiographic study of enamel in human primary teeth from a high fluoride area. Arch. Oral Biol., 23, 373-380.spa
dc.relation.referencesTovar, S., & Misnaza, S. (2016, February). Documento técnico política de flúor vs caries y fluorosis dental Bogotá. Ministerio de Salud y Protección Social.spa
dc.relation.referencesTranæus, S., Heinrich-Weltzien, R., Heinrich-Weltzien, J., Stösser, L., & Angmar-Månsson, B. (2001). Potential Applications and Limitations of Quantitative Light-induced Fluorescence in Dentistry. Med. Laser Appl., 16, 195–204.spa
dc.relation.referencesWarren, J., Kanellis, M., & Levy, S. (1999). Fluorosis of the primary dentition: What does it mean for permanent teeth? Journal of the American Dental Association, 130(3), 347-356.spa
dc.relation.referencesWarshawsky, H. (1971). A light and electron microscopic study of the nearly mature enamel of rat incisors. Anat. Rec, 169, 559-584.spa
dc.relation.referencesWhittaker, D. (1982). Structural variations in the surface zone of human tooth enamel observed by scanning electron microscopy. Archives of Oral Biology, 27, 383–392.spa
dc.relation.referencesWright, J. T., Chen, S. C., Hall, K. I., Yamauchi, I., & Bawden, J. W. (1996). Protein characterization of fluorosed human enamel. J Dent Res, 75(12), 1936-1941.spa
dc.rights.accessrightsinfo:eu-repo/semantics/closedAccess
dc.rights.accessrightshttps://purl.org/coar/access_right/c_14cb
dc.rights.localAcceso cerradospa
dc.subjectFluorosis dentalspa
dc.subjectDiagnósticospa
dc.subjectDientes primariosspa
dc.subjectHistologíaspa
dc.subjectFluorescenciaspa
dc.subjectMicrorradiografíaspa
dc.subject.keywordsEnamel fluorosisspa
dc.subject.keywordsDiagnosisspa
dc.subject.keywordsPrimary teethspa
dc.subject.keywordsHistologyspa
dc.subject.keywordsFluorescencespa
dc.subject.keywordsMicroradiographyspa
dc.subject.nlmWU 100
dc.titleUtilidad del diagnóstico visual (TFI) y por cuantificación de luz fluorescente (QLF) frente a microscopía de luz polarizada (PLM) y microrradiografía (TMR) en fluorosis leve y moderada en dientes primariosspa
dc.title.translatedUsefulness of visual (TFI) and QLF diagnosis versus PLM and TMR in mild and moderate fluorosis in primary teethspa
dc.type.coarhttps://purl.org/coar/resource_type/c_bdcc
dc.type.coarversionhttps://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.driverinfo:eu-repo/semantics/bachelorThesis
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersion
dc.type.localTesis/Trabajo de grado - Monografía - Maestríaspa

Archivos

Bloque original
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
Utilidad del diagnóstico visual (TFI) y por cuantificación de luz fluorescente (QLF) frente a microscopía de luz polarizada (PLM) y microrradiografía (TMR) en fluorosis leve y moderada en dientes primarios
Tamaño:
2.28 MB
Formato:
Adobe Portable Document Format
Descripción:
Utilidad del diagnóstico visual (TFI) y por cuantificación de luz fluorescente (QLF) frente a microscopía de luz polarizada (PLM) y microrradiografía (TMR) en fluorosis leve y moderada en dientes primarios
Descargar
Bloque de licencias
Mostrando 1 - 2 de 2
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descripción:
Descargar
No hay miniatura disponible
Nombre:
Acta de aprobación
Tamaño:
558.73 KB
Formato:
Adobe Portable Document Format
Descripción:
Acta de aprobación
Descargar

Colecciones

Maestría en Ciencias Odontológicas