Renal involvement at diagnosis of pediatric acute lymphoblastic leukemia

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dc.contributor.authorPrada Rico, Mayerly
dc.contributor.authorRodríguez-Cuellar, Carmen Inés
dc.contributor.authorArteaga Aya, Lucy Natalia
dc.contributor.authornuñez chates, claudia lorena
dc.contributor.authorGarcés-Sterling, Sandra Patricia
dc.contributor.authorPierotty, Mathieu
dc.contributor.authorGonzález Chaparro, Luz Esthella
dc.contributor.authorGastelbondo Amaya, Ricardo
dc.date.accessioned2020-07-29T00:06:14Z
dc.date.available2020-07-29T00:06:14Z
dc.date.issued2020
dc.description.abstractenglishAcute leukemia is the most common type of cancer in pediatric patients. This type of cancer accounts for a third of all childhood cancer cases. More than half of pediatric acute leukemia patients show signs and symptoms such as hepatomegaly, splenomegaly, pallor, fever and bruising at the time of diagnosis. In early stages of acute lymphoblastic leukemia (ALL), nephromegaly and other renal manifestations such as high blood pressure (HBP) and renal failure are uncommon, although renal infiltration and nephromegaly are common in advanced-stage pediatric patients. This is a retrospective case review with a critical appraisal of the existing evidence from the literature. We present a clinical case of a child with HBP associated with bilateral nephromegaly which resolved after chemotherapy treatment. This patient presented with HBP that required pharmacological treatment, likely owing to nephromegaly. All HBP secondary causes were rejected. Nephromegaly was resolved after chemotherapy treatment, and antihypertensive medication was discontinued. Nephromegaly and HBP are rare manifestations of ALL debut in pediatrics. The present case report illustrates this unusual combination and Suggests clinicians to consider malignancy as its causal factor, especially if the symptoms are accompanied by other suggestive extrarenal manifestations.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://dx.doi.org/10.4081%2Fpr.2020.8382
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn2036-7503
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlhttps://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/3598
dc.language.isoeng
dc.publisherPagePressspa
dc.publisher.journalPediatric reportsspa
dc.relation.ispartofseriesPediatric reports, 2036-7503, Vol. 12, Nro. 1, 2020, p. 29-33spa
dc.relation.urihttps://www.pagepress.org/journals/index.php/pr/article/view/8382
dc.rightsAttribution-NoDerivatives 4.0 International*
dc.rightsAttribution-NonCommercial-ShareAlike 4.0 International*
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.accessrightsAcceso abierto
dc.rights.creativecommons2020-04
dc.rights.localAcceso abiertospa
dc.rights.urihttps://creativecommons.org/licenses/by-nd/4.0/*
dc.rights.urihttps://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subjectNefromegaliaspa
dc.subjectHipertensiónspa
dc.subjectLeucemia linfoblástica agudaspa
dc.subject.decsEnfermedades renalesspa
dc.subject.decsLeucemiaspa
dc.subject.decsEnfermeras pediátricasspa
dc.titleRenal involvement at diagnosis of pediatric acute lymphoblastic leukemiaspa
dc.title.translatedRenal involvement at diagnosis of pediatric acute lymphoblastic leukemiaspa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

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