Simultaneous infection with enterobacteriaceae and pseudomonas aeruginosa harboring multiple carbapenemases in a returning traveler colonized with candida auris

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Khan, A., Shropshire, W.,Hanson, B._2020.pdf (652.26 KB)

Fecha

2020

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Publicado en

American Society for Microbiology Journals,1098-6596, Vol.64, Nro. 2, 2020, p. 1-6

Publicado por

American Society for Microbiology

URI

https://hdl.handle.net/20.500.12495/1934

URL de la fuente

https://aac.asm.org/content/64/2/e01466-19

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Abstract

We report our clinical experience treating a critically ill patient with polymicrobial infections due to multidrug-resistant Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa in a 56-year-old woman who received health care in India and was also colonized by Candida auris. A precision medicine approach using whole-genome sequencing revealed a multiplicity of mobile elements associated with NDM-1, NDM-5, and OXA-181 and, supplemented with susceptibility testing, guided the selection of rational antimicrobial therapy.

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Keywords

Candida auris, Enterobacteriaceae, Pseudomonas aeruginosa, Carbapenemase

Temáticas

Infecciones bacterianas
Análisis de secuencia de ADN
Resistencia a medicamentos

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