Anti-inflammatory effect of the hydroalcoholic extract of Muehlenbeckia tamnifolia (Kunth) meins leaves in a rat paw model

Vista sencilla de ítem
dc.contributor.authorJasbleidy, Mojica B.
dc.contributor.authorTorrenegra G., Ruben Dario
dc.contributor.authorPombo O., Luis M
dc.contributor.authorCadavid, Vanessa
dc.contributor.authorRodríguez Aguirre, Oscar Eduardo
dc.contributor.orcidRodríguez Aguirre, Oscar Eduardo [0000-0002-5934-0451]
dc.date.accessioned2020-06-16T19:06:39Z
dc.date.available2020-06-16T19:06:39Z
dc.date.issued2017
dc.description.abstractenglishInflammation is the local or systemic process by which a vascularized tissue defends itself against different situations through cellular and molecular mediators (references of molecules and inflammatory cells) that play a primordial role in the maintenance of the organism homeostasis. Classically its treatment has required the intervention of different agents like Anti-inflammatory Non-Steroidal (NSAIDs), Corticosteroids and biological therapy; these drugs, despite being effective, have many side effects. The purpose of this research is to evaluate the anti-inflammatory activity of the hydroalcoholic extract of leaves of the plant species Muehlembeckia tamnifolia (Kunth) Meins in a rat model. 20 female Wistar rats were randomly distributed in 4 groups of 5 animals each; inflammation was induced by the injection of 0.1 ml of a 1% lambda-carrageenan solution into the plantar aponeurosis of the right paw of the rats. Group I and II were treated with the complete Muehlembeckia, at different doses, Group III was positive control (Diclofenac) and Group IV was negative control (water). With the lowest dose of the extract had a lower net volume of inflammation as with diclofenac; same result was observed with the percentage inhibition of inflammation.eng
dc.format.mimetypeapplication/pdf
dc.identifier.instnameinstname:Universidad El Bosquespa
dc.identifier.issn1827-8620
dc.identifier.reponamereponame:Repositorio Institucional Universidad El Bosquespa
dc.identifier.repourlhttps://repositorio.unbosque.edu.co
dc.identifier.urihttps://hdl.handle.net/20.500.12495/3195
dc.language.isoeng
dc.publisherSILAEspa
dc.publisher.journalPharmacologyonlinespa
dc.relation.ispartofseriesPharmacologyonline, 1827-8620, Vol, 13, 2017, p. 13-22spa
dc.relation.urihttps://pharmacologyonline.silae.it/front/archives_2017_3
dc.rights.accessrightshttps://purl.org/coar/access_right/c_abf2
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightsAcceso abierto
dc.rights.creativecommons2017-12-30
dc.rights.localAcceso abiertospa
dc.subject.decsPlantas medicinalesspa
dc.subject.decsExperimentación animalspa
dc.subject.decsPatologíaspa
dc.subject.keywordsMuehlenbeckia tamnifoliaspa
dc.subject.keywordsAnti-inflammatory activityspa
dc.subject.keywordsCarrageenanspa
dc.titleAnti-inflammatory effect of the hydroalcoholic extract of Muehlenbeckia tamnifolia (Kunth) meins leaves in a rat paw modelspa
dc.title.translatedAnti-inflammatory effect of the hydroalcoholic extract of Muehlenbeckia tamnifolia (Kunth) meins leaves in a rat paw modelspa
dc.type.coarhttps://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.type.localArtículo de revista

Archivos

Bloque original
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
Jasbleidy, MB , Rubén D., TG , Luis M., PO , Vanessa, CG , Oscar E., RA _2017.pdf
Tamaño:
1.7 MB
Formato:
Adobe Portable Document Format
Descripción:
Descargar
Bloque de licencias
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descripción:
Descargar

Colecciones

Artículos